Pikromycin

Pikromycin is a lipid of Polyketides (PK) class. The involved functions are known as Anabolism, Process, Cytokinesis, Mutation and Biochemical Pathway. Pikromycin often locates in soluble. The associated genes with Pikromycin are SLC7A1 gene, Homologous Gene, Gene Clusters, Polypeptides and THEMIS gene.

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Introduction

To understand associated biological information of Pikromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Pikromycin?

There are no associated biomedical information in the current reference collection.

No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with Pikromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Pikromycin?

Related references are published most in these journals:

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What functions are associated with Pikromycin?


Related references are published most in these journals:

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What lipids are associated with Pikromycin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Pikromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Pikromycin?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Pikromycin

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Authors Title Published Journal PubMed Link
Yin Y et al. Expression and kinetic analysis of the substrate specificity of modules 5 and 6 of the picromycin/methymycin polyketide synthase. 2003 J. Am. Chem. Soc. pmid:12733905
Zhao L et al. Beta-glucosylation as a part of self-resistance mechanism in methymycin/pikromycin producing strain Streptomyces venezuelae. 2003 Biochemistry pmid:14674753
Beck BJ et al. Iterative chain elongation by a pikromycin monomodular polyketide synthase. 2003 J. Am. Chem. Soc. pmid:12696866
Watanabe K et al. Understanding substrate specificity of polyketide synthase modules by generating hybrid multimodular synthases. 2003 J. Biol. Chem. pmid:12923197
Beck BJ et al. Substrate recognition and channeling of monomodules from the pikromycin polyketide synthase. 2003 J. Am. Chem. Soc. pmid:14531700
Lu H et al. Expression, site-directed mutagenesis, and steady state kinetic analysis of the terminal thioesterase domain of the methymycin/picromycin polyketide synthase. 2002 Biochemistry pmid:12379101
Kim BS et al. Biochemical evidence for an editing role of thioesterase II in the biosynthesis of the polyketide pikromycin. 2002 J. Biol. Chem. pmid:12368286
Kim BS et al. An unexpected interaction between the modular polyketide synthases, erythromycin DEBS1 and pikromycin PikAIV, leads to efficient triketide lactone synthesis. 2002 Biochemistry pmid:12196022
Tsai SC et al. Insights into channel architecture and substrate specificity from crystal structures of two macrocycle-forming thioesterases of modular polyketide synthases. 2002 Biochemistry pmid:12379102
Beck BJ et al. The hidden steps of domain skipping: macrolactone ring size determination in the pikromycin modular polyketide synthase. 2002 Chem. Biol. pmid:12031664