Pikromycin

Pikromycin is a lipid of Polyketides (PK) class. The involved functions are known as Anabolism, Process, Cytokinesis, Mutation and Biochemical Pathway. Pikromycin often locates in soluble. The associated genes with Pikromycin are SLC7A1 gene, Homologous Gene, Gene Clusters, Polypeptides and THEMIS gene.

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Introduction

To understand associated biological information of Pikromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Pikromycin?

There are no associated biomedical information in the current reference collection.

No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with Pikromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Pikromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Pikromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Pikromycin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Pikromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Pikromycin?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Pikromycin

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Authors Title Published Journal PubMed Link
O'Connor SE Cyclization of natural products. 2006 Nat. Chem. Biol. pmid:16983382
Venkatraman L et al. Total synthesis of narbonolide and biotransformation to pikromycin. 2006 J. Org. Chem. pmid:17168607
Lee SK et al. Neopikromycin and novapikromycin from the pikromycin biosynthetic pathway of Streptomyces venezuelae. 2006 J. Nat. Prod. pmid:16724858
Wu J et al. Polyketide double bond biosynthesis. Mechanistic analysis of the dehydratase-containing module 2 of the picromycin/methymycin polyketide synthase. 2005 J. Am. Chem. Soc. pmid:16332089
Wu J et al. Chain elongation, macrolactonization, and hydrolysis of natural and reduced hexaketide substrates by the picromycin/methymycin polyketide synthase. 2005 Angew. Chem. Int. Ed. Engl. pmid:16247819
Aldrich CC et al. Biochemical investigation of pikromycin biosynthesis employing native penta- and hexaketide chain elongation intermediates. 2005 J. Am. Chem. Soc. pmid:15941278
Borisova SA et al. Characterization of the glycosyltransferase activity of desVII: analysis of and implications for the biosynthesis of macrolide antibiotics. 2004 J. Am. Chem. Soc. pmid:15161264
Hong JS et al. New olivosyl derivatives of methymycin/pikromycin from an engineered strain of Streptomyces venezuelae. 2004 FEMS Microbiol. Lett. pmid:15358425
Kim BS et al. An efficient method for creation and functional analysis of libraries of hybrid type I polyketide synthases. 2004 Protein Eng. Des. Sel. pmid:15067106
Lee SK et al. The role of erythromycin C-12 hydroxylase, EryK, as a substitute for PikC hydroxylase in pikromycin biosynthesis. 2004 Bioorg. Chem. pmid:15530995