phytosphingosine

phytosphingosine is a lipid of Sphingolipids (SP) class. Phytosphingosine is associated with abnormalities such as Infection, Nodule, Dehydration, Neuropathy and nervous system disorder. The involved functions are known as Saturated, sphingomyelin synthase activity, Heat-Shock Response, Cell Growth and Apoptosis. Phytosphingosine often locates in Clone, Protoplasm, Mitochondria, soluble and Cytoplasmic matrix. The associated genes with phytosphingosine are SGMS1 gene, BCL2 gene, Chromatin, Homologous Gene and DLEU2 gene. The related lipids are Sphingolipids, inositolphosphorylceramide, Phosphatidylserines, dihydroceramide and Fatty Acids. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of phytosphingosine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with phytosphingosine?

phytosphingosine is suspected in Infection, Nodule, Dehydration, Neuropathy, nervous system disorder, Atopic and other diseases in descending order of the highest number of associated sentences.

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No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with phytosphingosine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with phytosphingosine?

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What functions are associated with phytosphingosine?


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What lipids are associated with phytosphingosine?

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What genes are associated with phytosphingosine?

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What common seen animal models are associated with phytosphingosine?

Knock-out

Knock-out are used in the study 'Role for de novo sphingoid base biosynthesis in the heat-induced transient cell cycle arrest of Saccharomyces cerevisiae.' (Jenkins GM and Hannun YA, 2001) and Knock-out are used in the study 'SVF1 regulates cell survival by affecting sphingolipid metabolism in Saccharomyces cerevisiae.' (Brace JL et al., 2007).

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NCBI Entrez Crosslinks

All references with phytosphingosine

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Authors Title Published Journal PubMed Link
Pepe D et al. Protein transduction domain-containing microemulsions as cutaneous delivery systems for an anticancer agent. 2013 J Pharm Sci pmid:23436680
Lachaud C et al. 14-3-3-regulated Ca(2+)-dependent protein kinase CPK3 is required for sphingolipid-induced cell death in Arabidopsis. 2013 Cell Death Differ. pmid:22935611
Colabardini AC et al. Functional characterization of Aspergillus nidulans ypkA, a homologue of the mammalian kinase SGK. 2013 PLoS ONE pmid:23472095
Paul S and Moye-Rowley WS Functional analysis of an ATP-binding cassette transporter protein from Aspergillus fumigatus by heterologous expression in Saccharomyces cerevisiae. 2013 Fungal Genet. Biol. pmid:23796749
KaraÅ› MA and Russa R New long chain bases in lipophosphonoglycan of Acanthamoeba castellanii. 2013 Lipids pmid:23636605
Murakami I et al. Improved high-fat diet-induced glucose intolerance by an oral administration of phytosphingosine. 2013 Biosci. Biotechnol. Biochem. pmid:23291756
Sigruener A et al. Effects of sphingoid bases on the sphingolipidome in early keratinocyte differentiation. 2013 Exp. Dermatol. pmid:24079743
Cichewicz A et al. Cutaneous delivery of α-tocopherol and lipoic acid using microemulsions: influence of composition and charge. 2013 J. Pharm. Pharmacol. pmid:23647675
Fischer CL et al. Sphingoid bases are taken up by Escherichia coli and Staphylococcus aureus and induce ultrastructural damage. 2013 Skin Pharmacol Physiol pmid:23128426
Klose C et al. Flexibility of a eukaryotic lipidome--insights from yeast lipidomics. 2012 PLoS ONE pmid:22529973