Glycochenodeoxycholic acid

Glycochenodeoxycholic acid is a lipid of Sterol Lipids (ST) class. Glycochenodeoxycholic acid is associated with abnormalities such as Cholestasis. The involved functions are known as Apoptosis, Process, Cytokinesis and Necrosis. Glycochenodeoxycholic acid often locates in Cell surface. The associated genes with Glycochenodeoxycholic acid are SLC10A1 gene, TNFSF10 gene, AKR1C2 gene and HSPA5 gene. The related lipids are glycoursodeoxycholic acid.

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Introduction

To understand associated biological information of Glycochenodeoxycholic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Glycochenodeoxycholic acid?

Glycochenodeoxycholic acid is suspected in Cholestasis and other diseases in descending order of the highest number of associated sentences.

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No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with Glycochenodeoxycholic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Glycochenodeoxycholic acid?

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What functions are associated with Glycochenodeoxycholic acid?


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What lipids are associated with Glycochenodeoxycholic acid?

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What genes are associated with Glycochenodeoxycholic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Glycochenodeoxycholic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Glycochenodeoxycholic acid

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Authors Title Published Journal PubMed Link
Horváth G et al. Structural determinants of ligand binding in the ternary complex of human ileal bile acid binding protein with glycocholate and glycochenodeoxycholate obtained from solution NMR. 2016 FEBS J. pmid:26613247
González-Rubio S et al. AP-1 Inhibition by SR 11302 Protects Human Hepatoma HepG2 Cells from Bile Acid-Induced Cytotoxicity by Restoring the NOS-3 Expression. 2016 PLoS ONE pmid:27490694
Lang E et al. Bile Acid-Induced Suicidal Erythrocyte Death. 2016 Cell. Physiol. Biochem. pmid:27050423
Webster CR and Anwer MS Hydrophobic bile acid apoptosis is regulated by sphingosine-1-phosphate receptor 2 in rat hepatocytes and human hepatocellular carcinoma cells. 2016 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:26999807
Woolbright BL et al. Bile Acid-Induced Toxicity in HepaRG Cells Recapitulates the Response in Primary Human Hepatocytes. 2016 Basic Clin. Pharmacol. Toxicol. pmid:26176423
Sellinger M et al. Ursodeoxycholyl lysophosphatidylethanolamide inhibits cholestasis- and hypoxia-induced apoptosis by upregulating antiapoptosis proteins. 2015 Exp. Biol. Med. (Maywood) pmid:25125499
James L et al. Comparison of Bile Acids and Acetaminophen Protein Adducts in Children and Adolescents with Acetaminophen Toxicity. 2015 PLoS ONE pmid:26208104
Sommerfeld A et al. Tauroursodeoxycholate Protects Rat Hepatocytes from Bile Acid-Induced Apoptosis via β1-Integrin- and Protein Kinase A-Dependent Mechanisms. 2015 Cell. Physiol. Biochem. pmid:26044599
Woolbright BL et al. Bile acid-induced necrosis in primary human hepatocytes and in patients with obstructive cholestasis. 2015 Toxicol. Appl. Pharmacol. pmid:25636263
Kowal JM et al. Bile acid effects are mediated by ATP release and purinergic signalling in exocrine pancreatic cells. 2015 Cell Commun. Signal pmid:26050734