Glycochenodeoxycholic acid

Glycochenodeoxycholic acid is a lipid of Sterol Lipids (ST) class. Glycochenodeoxycholic acid is associated with abnormalities such as Cholestasis. The involved functions are known as Apoptosis, Process, Cytokinesis and Necrosis. Glycochenodeoxycholic acid often locates in Cell surface. The associated genes with Glycochenodeoxycholic acid are SLC10A1 gene, TNFSF10 gene, AKR1C2 gene and HSPA5 gene. The related lipids are glycoursodeoxycholic acid.

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Introduction

To understand associated biological information of Glycochenodeoxycholic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Glycochenodeoxycholic acid?

Glycochenodeoxycholic acid is suspected in Cholestasis and other diseases in descending order of the highest number of associated sentences.

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No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with Glycochenodeoxycholic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Glycochenodeoxycholic acid?

Related references are published most in these journals:

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What functions are associated with Glycochenodeoxycholic acid?


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What lipids are associated with Glycochenodeoxycholic acid?

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What genes are associated with Glycochenodeoxycholic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Glycochenodeoxycholic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Glycochenodeoxycholic acid

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Authors Title Published Journal PubMed Link
Maléth J et al. Non-conjugated chenodeoxycholate induces severe mitochondrial damage and inhibits bicarbonate transport in pancreatic duct cells. 2011 Gut pmid:20732916
Wang K et al. iNOS/NO signaling regulates apoptosis induced by glycochenodeoxycholate in hepatocytes. 2011 Cell. Signal. pmid:21693187
Wang K et al. C/EBPα and C/EBPβ binding proteins modulate hepatocyte apoptosis through iNOS signaling pathway. 2011 Biochim. Biophys. Acta pmid:21539866
Liao M et al. Role of bile salt in regulating Mcl-1 phosphorylation and chemoresistance in hepatocellular carcinoma cells. 2011 Mol. Cancer pmid:21507240
González R et al. Cytoprotective properties of rifampicin are related to the regulation of detoxification system and bile acid transporter expression during hepatocellular injury induced by hydrophobic bile acids. 2011 J Hepatobiliary Pancreat Sci pmid:21526375
Johnston A et al. cAMP-guanine exchange factor protection from bile acid-induced hepatocyte apoptosis involves glycogen synthase kinase regulation of c-Jun NH2-terminal kinase. 2011 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:21546580
Roberts RE et al. The relationship between postprandial bile acid concentration, GLP-1, PYY and ghrelin. 2011 Clin. Endocrinol. (Oxf) pmid:21039722
Zanzoni S et al. Structural requirements for cooperativity in ileal bile acid-binding proteins. 2011 J. Biol. Chem. pmid:21917914
Hohenester S et al. Phosphatidylinositol-3-kinase p110γ contributes to bile salt-induced apoptosis in primary rat hepatocytes and human hepatoma cells. 2010 J. Hepatol. pmid:20675006
Gotoh K et al. Bile acid-induced virulence gene expression of Vibrio parahaemolyticus reveals a novel therapeutic potential for bile acid sequestrants. 2010 PLoS ONE pmid:20967223