Glycochenodeoxycholic acid

Glycochenodeoxycholic acid is a lipid of Sterol Lipids (ST) class. Glycochenodeoxycholic acid is associated with abnormalities such as Cholestasis. The involved functions are known as Apoptosis, Process, Cytokinesis and Necrosis. Glycochenodeoxycholic acid often locates in Cell surface. The associated genes with Glycochenodeoxycholic acid are SLC10A1 gene, TNFSF10 gene, AKR1C2 gene and HSPA5 gene. The related lipids are glycoursodeoxycholic acid.

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Introduction

To understand associated biological information of Glycochenodeoxycholic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Glycochenodeoxycholic acid?

Glycochenodeoxycholic acid is suspected in Cholestasis and other diseases in descending order of the highest number of associated sentences.

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Disease Cross reference Weighted score Related literature
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No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with Glycochenodeoxycholic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Glycochenodeoxycholic acid?

Related references are published most in these journals:

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What functions are associated with Glycochenodeoxycholic acid?


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What lipids are associated with Glycochenodeoxycholic acid?

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What genes are associated with Glycochenodeoxycholic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Glycochenodeoxycholic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Glycochenodeoxycholic acid

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Authors Title Published Journal PubMed Link
Webster CR et al. Protein kinase Cδ protects against bile acid apoptosis by suppressing proapoptotic JNK and BIM pathways in human and rat hepatocytes. 2014 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:25359536
Yu T et al. Decreasing mitochondrial fission prevents cholestatic liver injury. 2014 J. Biol. Chem. pmid:25342755
Lozano E et al. Cocarcinogenic effects of intrahepatic bile acid accumulation in cholangiocarcinoma development. 2014 Mol. Cancer Res. pmid:24255171
Cross AJ et al. A prospective study of serum metabolites and colorectal cancer risk. 2014 Cancer pmid:24894841
Penno CA et al. 11β-Hydroxysteroid dehydrogenase-1 is involved in bile acid homeostasis by modulating fatty acid transport protein-5 in the liver of mice. 2014 Mol Metab pmid:25061560
Wang K et al. Hepatic apoptosis can modulate liver fibrosis through TIMP1 pathway. 2013 Apoptosis pmid:23456624
Schulz S et al. Progressive stages of mitochondrial destruction caused by cell toxic bile salts. 2013 Biochim. Biophys. Acta pmid:23685124
Tian Z et al. Cytochrome P450 107U1 is required for sporulation and antibiotic production in Streptomyces coelicolor. 2013 Arch. Biochem. Biophys. pmid:23357279
Chen Y et al. Mitofusin 2 protects hepatocyte mitochondrial function from damage induced by GCDCA. 2013 PLoS ONE pmid:23755235
Woudenberg-Vrenken TE et al. Metformin protects rat hepatocytes against bile acid-induced apoptosis. 2013 PLoS ONE pmid:23951244