Glycochenodeoxycholic acid

Glycochenodeoxycholic acid is a lipid of Sterol Lipids (ST) class. Glycochenodeoxycholic acid is associated with abnormalities such as Cholestasis. The involved functions are known as Apoptosis, Process, Cytokinesis and Necrosis. Glycochenodeoxycholic acid often locates in Cell surface. The associated genes with Glycochenodeoxycholic acid are SLC10A1 gene, TNFSF10 gene, AKR1C2 gene and HSPA5 gene. The related lipids are glycoursodeoxycholic acid.

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Introduction

To understand associated biological information of Glycochenodeoxycholic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Glycochenodeoxycholic acid?

Glycochenodeoxycholic acid is suspected in Cholestasis and other diseases in descending order of the highest number of associated sentences.

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No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with Glycochenodeoxycholic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Glycochenodeoxycholic acid?

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What functions are associated with Glycochenodeoxycholic acid?


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What lipids are associated with Glycochenodeoxycholic acid?

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What genes are associated with Glycochenodeoxycholic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Glycochenodeoxycholic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Glycochenodeoxycholic acid

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Authors Title Published Journal PubMed Link
Karimian G et al. Sphingosine kinase-1 inhibition protects primary rat hepatocytes against bile salt-induced apoptosis. 2013 Biochim. Biophys. Acta pmid:23816565
Zhang JH et al. Potent stimulation of fibroblast growth factor 19 expression in the human ileum by bile acids. 2013 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:23518683
Wang K et al. Hepatic apoptosis can modulate liver fibrosis through TIMP1 pathway. 2013 Apoptosis pmid:23456624
Heinen CA et al. Ion pairing with bile salts modulates intestinal permeability and contributes to food-drug interaction of BCS class III compound trospium chloride. 2013 Mol. Pharm. pmid:23750707
Liang S et al. Effect of quercetin 7-rhamnoside on glycochenodeoxycholic acid-induced L-02 human normal liver cell apoptosis. 2013 Int. J. Mol. Med. pmid:23756642
Horváth G et al. Internal motions and exchange processes in human ileal bile acid binding protein as studied by backbone (15)N nuclear magnetic resonance spectroscopy. 2012 Biochemistry pmid:22329738
Karimian G et al. Angiotensin II protects primary rat hepatocytes against bile salt-induced apoptosis. 2012 PLoS ONE pmid:23300732
Brites D The evolving landscape of neurotoxicity by unconjugated bilirubin: role of glial cells and inflammation. 2012 Front Pharmacol pmid:22661946
Karlgren M et al. In vitro and in silico strategies to identify OATP1B1 inhibitors and predict clinical drug-drug interactions. 2012 Pharm. Res. pmid:21861202
Woolbright BL and Jaeschke H Novel insight into mechanisms of cholestatic liver injury. 2012 World J. Gastroenterol. pmid:23049206