Ganglioside GT1

Ganglioside GT1 is a lipid of Sphingolipids (SP) class. Ganglioside gt1 is associated with abnormalities such as Neuropathy, Peripheral Neuropathy, Autoimmune Syndrome Type II, Polyglandular, protrusion and Neuritis. The involved functions are known as Binding (Molecular Function), Adjudication, Process, Drug Interactions and Macromolecular alteration. Ganglioside gt1 often locates in Entire nervous system, nucleocapsid location, Membrane, Face and cell body (neuron). The associated genes with Ganglioside GT1 are Homologous Gene, N-dodecyl-L-lysine amide, G-substrate, synthetic peptide and APP gene. The related lipids are GT1b-ganglioside, trisialaoganglioside GT1a, IV(4)-galactosyl-N-acetylganglioside GD1a, sialogangliosides and polysialoganglioside.

Cross Reference

Introduction

To understand associated biological information of Ganglioside GT1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Ganglioside GT1?

Ganglioside GT1 is suspected in Neuropathy, Peripheral Neuropathy, Autoimmune Syndrome Type II, Polyglandular, protrusion, Neuritis, Gastrointestinal infections and other diseases in descending order of the highest number of associated sentences.

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PubChem Associated disorders and diseases

What pathways are associated with Ganglioside GT1

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Ganglioside GT1?

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What functions are associated with Ganglioside GT1?


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What lipids are associated with Ganglioside GT1?

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What genes are associated with Ganglioside GT1?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Ganglioside GT1?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Ganglioside GT1

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Authors Title Published Journal PubMed Link
Zheng Y et al. Efficient biotransformation of polysialogangliosides for preparation of GM1 by Cellulosimicrobium sp. 21. 2014 Molecules pmid:25299818
Prendergast J et al. Ganglioside regulation of AMPA receptor trafficking. 2014 J. Neurosci. pmid:25253868
Burns JR and Baldwin MR Tetanus neurotoxin utilizes two sequential membrane interactions for channel formation. 2014 J. Biol. Chem. pmid:24973217
Willjes G et al. Botulinum neurotoxin G binds synaptotagmin-II in a mode similar to that of serotype B: tyrosine 1186 and lysine 1191 cause its lower affinity. 2013 Biochemistry pmid:23647335
Przedpelski A et al. Enhancing the protective immune response against botulism. 2013 Infect. Immun. pmid:23670557
Whitemarsh RC et al. Model for studying Clostridium botulinum neurotoxin using differentiated motor neuron-like NG108-15 cells. 2012 Biochem. Biophys. Res. Commun. pmid:23000406
Venkateshwari S and Veluraja K Conformational analysis of GT1B ganglioside and its interaction with botulinum neurotoxin type B: a study by molecular modeling and molecular dynamics. 2012 J. Biomol. Struct. Dyn. pmid:22746533
Sun S et al. Botulinum neurotoxins B and E translocate at different rates and exhibit divergent responses to GT1b and low pH. 2012 Biochemistry pmid:22720883
Watanabe S et al. Involvement of ganglioside GT1b in glutamate release from neuroblastoma cells. 2012 Neurosci. Lett. pmid:22565021
Singh MK et al. Deletion mutant comprising 198 residues of BoNT/A toxin receptor binding domain retained gt1b binding property but failed to induce protective antibody response in a mouse model. 2012 Protein Pept. Lett. pmid:22486648