Ganglioside GT1

Ganglioside GT1 is a lipid of Sphingolipids (SP) class. Ganglioside gt1 is associated with abnormalities such as Neuropathy, Peripheral Neuropathy, Autoimmune Syndrome Type II, Polyglandular, protrusion and Neuritis. The involved functions are known as Binding (Molecular Function), Adjudication, Process, Drug Interactions and Macromolecular alteration. Ganglioside gt1 often locates in Entire nervous system, nucleocapsid location, Membrane, Face and cell body (neuron). The associated genes with Ganglioside GT1 are Homologous Gene, N-dodecyl-L-lysine amide, G-substrate, synthetic peptide and APP gene. The related lipids are GT1b-ganglioside, trisialaoganglioside GT1a, IV(4)-galactosyl-N-acetylganglioside GD1a, sialogangliosides and polysialoganglioside.

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Introduction

To understand associated biological information of Ganglioside GT1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Ganglioside GT1?

Ganglioside GT1 is suspected in Neuropathy, Peripheral Neuropathy, Autoimmune Syndrome Type II, Polyglandular, protrusion, Neuritis, Gastrointestinal infections and other diseases in descending order of the highest number of associated sentences.

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PubChem Associated disorders and diseases

What pathways are associated with Ganglioside GT1

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Ganglioside GT1?

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What functions are associated with Ganglioside GT1?


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What lipids are associated with Ganglioside GT1?

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What genes are associated with Ganglioside GT1?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Ganglioside GT1?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Ganglioside GT1

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Authors Title Published Journal PubMed Link
Urbina P et al. Effects of bilayer composition and physical properties on the phospholipase C and sphingomyelinase activities of Clostridium perfringens α-toxin. 2011 Biochim. Biophys. Acta pmid:20727345
Qian M and Tsai B Lipids and proteins act in opposing manners to regulate polyomavirus infection. 2010 J. Virol. pmid:20668088
Cao T et al. Ganglioside GD1a suppression of NOS2 expression via ERK1 pathway in mouse osteosarcoma FBJ cells. 2010 J. Cell. Biochem. pmid:20589721
Gavella M et al. Modulation of ROS production in human leukocytes by ganglioside micelles. 2010 Braz. J. Med. Biol. Res. pmid:20878014
Chung ES et al. GT1b-induced neurotoxicity is mediated by the Akt/GSK-3/tau signaling pathway but not caspase-3 in mesencephalic dopaminergic neurons. 2010 BMC Neurosci pmid:20540782
de Freitas RM et al. Neurochemical changes on oxidative stress in rat hippocampus during acute phase of pilocarpine-induced seizures. 2010 Pharmacol. Biochem. Behav. pmid:19800361
Dong Y et al. GM1 / GD1b / GA1 synthase expression results in the reduced cancer phenotypes with modulation of composition and raft-localization of gangliosides in a melanoma cell line. 2010 Cancer Sci. pmid:20594196
Ebrahimi F et al. Production and characterization of a recombinant chimeric antigen consisting botulinum neurotoxin serotypes A, B and E binding subdomains. 2010 J Toxicol Sci pmid:20118620
Behrensdorf-Nicol HA et al. In vitro determination of tetanus toxicity by an endopeptidase assay linked to a ganglioside-binding step. 2010 Toxicol In Vitro pmid:20036726
Gavella M et al. Ganglioside GT1b protects human spermatozoa from hydrogen peroxide-induced DNA and membrane damage. 2010 Int. J. Androl. pmid:19490186