Ganglioside GT1

Ganglioside GT1 is a lipid of Sphingolipids (SP) class. Ganglioside gt1 is associated with abnormalities such as Neuropathy, Peripheral Neuropathy, Autoimmune Syndrome Type II, Polyglandular, protrusion and Neuritis. The involved functions are known as Binding (Molecular Function), Adjudication, Process, Drug Interactions and Macromolecular alteration. Ganglioside gt1 often locates in Entire nervous system, nucleocapsid location, Membrane, Face and cell body (neuron). The associated genes with Ganglioside GT1 are Homologous Gene, N-dodecyl-L-lysine amide, G-substrate, synthetic peptide and APP gene. The related lipids are GT1b-ganglioside, trisialaoganglioside GT1a, IV(4)-galactosyl-N-acetylganglioside GD1a, sialogangliosides and polysialoganglioside.

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Introduction

To understand associated biological information of Ganglioside GT1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Ganglioside GT1?

Ganglioside GT1 is suspected in Neuropathy, Peripheral Neuropathy, Autoimmune Syndrome Type II, Polyglandular, protrusion, Neuritis, Gastrointestinal infections and other diseases in descending order of the highest number of associated sentences.

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PubChem Associated disorders and diseases

What pathways are associated with Ganglioside GT1

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Ganglioside GT1?

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What functions are associated with Ganglioside GT1?


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What lipids are associated with Ganglioside GT1?

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What genes are associated with Ganglioside GT1?

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What common seen animal models are associated with Ganglioside GT1?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Ganglioside GT1

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Authors Title Published Journal PubMed Link
Miller CE et al. Integration of ganglioside GT1b receptor into DPPE and DPPC phospholipid monolayers: an X-ray reflectivity and grazing-incidence diffraction study. 2008 Biophys. J. pmid:18599631
Townson KH et al. Glycosphingolipid depletion in PC12 cells using iminosugars protects neuronal membranes from anti-ganglioside antibody mediated injury. 2008 J. Neuroimmunol. pmid:18684516
Williams G et al. Ganglioside inhibition of neurite outgrowth requires Nogo receptor function: identification of interaction sites and development of novel antagonists. 2008 J. Biol. Chem. pmid:18411262
Kim BH et al. Expression of ganglioside GT1b in mouse embryos at different developmental stages after cryopreservation. 2008 Arch. Pharm. Res. pmid:18277613
Kaida K et al. Anti-ganglioside complex antibodies associated with severe disability in GBS. 2007 J. Neuroimmunol. pmid:17113161
Lee DH et al. Effects of daunorubicin on ganglioside expression and neuronal differentiation of mouse embryonic stem cells. 2007 Biochem. Biophys. Res. Commun. pmid:17707770
Peng YF et al. Development of a large scale process for the conversion of polysialogangliosides to monosialotetrahexosylganglioside with a novel strain of Brevibacterium casei producing sialidase. 2007 Biotechnol. Lett. pmid:17415532
Baldwin MR et al. Botulinum neurotoxin B-host receptor recognition: it takes two receptors to tango. 2007 Nat. Struct. Mol. Biol. pmid:17203068
Slade AL et al. In situ scanning probe microscopy studies of tetanus toxin-membrane interactions. 2006 Biophys. J. pmid:16997879
Attrill H et al. Siglec-7 undergoes a major conformational change when complexed with the alpha(2,8)-disialylganglioside GT1b. 2006 J. Biol. Chem. pmid:16895906