Disease MeSH term: Cell Transformation, Neoplastic

Possible associated with:

Structure name description Reference count
3-O-Methylquercetin 3-O-Methylquercetin is a lipid of Polyketides (PK) class. 3-o-methylquercetin is associated with abnormalities such as Colitis, Hemorrhagic diarrhea and Diabetes. The involved functions are known as Inflammation, Trans-Activation (Genetics), Signal Transduction, Binding, Competitive and Antiinflammatory Effect. 3-o-methylquercetin often locates in Mucous Membrane. The associated genes with 3-O-Methylquercetin are IL2 gene, Human gene and ABCB1 gene. The related experimental models are Streptozotocin Diabetes. 364
kaempferol kaempferol is a lipid of Polyketides (PK) class. Kaempferol is associated with abnormalities such as Cardiovascular Diseases, IMMUNE SUPPRESSION, Inflammatory disorder, Dermatitis, Atopic and Asthma. The involved functions are known as enzyme activity, antagonists, DNA Binding, Anabolism and Transcription, Genetic. Kaempferol often locates in aryl hydrocarbon receptor complex, Cytoplasmic matrix, soluble, BL21 and Vacuole. The associated genes with kaempferol are CYP1A1 gene, AHR gene, Genes, Reporter, Candidate Disease Gene and Alleles. The related lipids are Fatty Acids, Steroids, Lipopolysaccharides, Total cholesterol and Palmitates. The related experimental models are Knock-out, Xenograft Model, Breast Cancer Model, Disease model and Animal Disease Models. 3675
quercetin quercetin is a lipid of Polyketides (PK) class. Quercetin is associated with abnormalities such as Coronary heart disease, Myocardial Infarction, Cirrhosis, Coronary Arteriosclerosis and Vascular ring. The involved functions are known as Vasodilation, physiological aspects, Fermentation, Process and Ingredient. Quercetin often locates in Arterial system, Endothelium, Skin, Endothelium, Vascular and Tissue specimen. The associated genes with quercetin are P4HTM gene, SULT gene, UGT1A1 gene, ARHGAP26 gene and PLXNB1 gene. The related lipids are blood lipid, Promega, Steroids, Phosphatidylserines and Fatty Acids. The related experimental models are Knock-out, Mouse Model, Xenograft Model, Tissue Model and Cancer Model. 5377
apigenin apigenin is a lipid of Polyketides (PK) class. Apigenin is associated with abnormalities such as Morphologically altered structure, Chimera disorder, Hypertensive disease, infection induced and Infection. The involved functions are known as inhibitors, Gene Expression, Process, Metabolic Inhibition and Cell Death. Apigenin often locates in Vacuole, Cytoplasmic matrix, Cytoplasm, Tissue membrane and Membrane. The associated genes with apigenin are MSMP gene, BCL2 gene, PTGS2 gene, Chromatin and SLC33A1 gene. The related lipids are Lipopolysaccharides, Steroids, 1-Butanol, agosterol A and Butyrates. The related experimental models are Mouse Model, Tissue Model, Knock-out, Xenograft Model and Disease model. 4250
luteolin luteolin is a lipid of Polyketides (PK) class. Luteolin is associated with abnormalities such as Morphologically altered structure, Nodule, retinal toxicity, CLEFT LIP, CONGENITAL HEALED and Ischemia. The involved functions are known as Metabolic Inhibition, Cell Death, Caspase Activation, activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway and protein kinase C activity. Luteolin often locates in Mitochondria, Cell-Free System, Protoplasm, Membrane and Body tissue. The associated genes with luteolin are BCL2 gene, TNFSF10 gene, BCL2L1 gene, XIAP gene and MCL1 gene. The related lipids are Lipopolysaccharides, Sterols, blood lipid, Fatty Acids and Steroids. The related experimental models are Xenograft Model, Mouse Model, Experimental Autoimmune Encephalomyelitis, Knock-out and Cancer Model. 3284
Zapotin Zapotin is a lipid of Polyketides (PK) class. 16
FLAVONE FLAVONE is a lipid of Polyketides (PK) class. Flavone is associated with abnormalities such as Cardiovascular Diseases, Cerebrovascular accident, DERMATITIS HERPETIFORMIS, FAMILIAL, Hyperinsulinism and Inflammatory disorder. The involved functions are known as Oxidation-Reduction, Metabolic Inhibition, Inflammation, Phosphorylation and antioxidant activity. Flavone often locates in Endothelium, Hepatic, Protoplasm, Body tissue and Extracellular. The associated genes with FLAVONE are ICAM1 gene, BCL2L1 gene, MYC gene, TP53 gene and cytochrome c''. The related lipids are Promega, Steroids and Total cholesterol. The related experimental models are Knock-out, Disease model and Animal Disease Models. 2093
chrysin chrysin is a lipid of Polyketides (PK) class. Chrysin is associated with abnormalities such as Unconjugated hyperbilirubinemia, Metabolic Diseases, Hypogonadism, Renal tubular disorder and Colitis. The involved functions are known as Hypoxia, enzyme activity, Oxidation, inhibitors and Cell Survival. Chrysin often locates in Protoplasm, Plasma membrane, Back, Extracellular and Mitochondria. The associated genes with chrysin are CFB gene, P4HTM gene, UGT1A9 gene, CYP1A1 gene and UGT1A1 gene. The related lipids are Promega, estradiol-3-glucuronide, Steroids and Lipopolysaccharides. The related experimental models are Mouse Model. 1085
acacetin acacetin is a lipid of Polyketides (PK) class. Acacetin is associated with abnormalities such as Cardiovascular Diseases, Janiceps and Meralgia paresthetica. The involved functions are known as Cell Cycle Arrest, Cell Growth, Agent, Metabolic Inhibition and Cell Death. Acacetin often locates in Protoplasm, Membrane, Plasma membrane, Capillary blood and Endothelium. The associated genes with acacetin are CDKN1B gene, KCNH2 gene, MSMP gene, COX8A gene and PI3 gene. The related lipids are Lipopolysaccharides. The related experimental models are Xenograft Model. 277
baicalein baicalein is a lipid of Polyketides (PK) class. Baicalein is associated with abnormalities such as Neurodegenerative Disorders, Fibrillation, Hypertensive disease, Aortic coarctation and Coronary Occlusion. The involved functions are known as Anabolism, Polymerization, Process, inhibitors and Pathogenesis. Baicalein often locates in Membrane, Lipid Bilayers, soluble, Cell-Free System and Protoplasm. The associated genes with baicalein are P4HTM gene, BIRC5 gene, TSPO gene, SHOC2 gene and XIAP gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, iodoresiniferatoxin, Lipopolysaccharides and 17-octadecynoic acid. The related experimental models are Knock-out, Mouse Model and Parkinsonism, Experimental. 1997
Oroxylin A Oroxylin A is a lipid of Polyketides (PK) class. 180
Nobiletin Nobiletin is a lipid of Polyketides (PK) class. Nobiletin is associated with abnormalities such as Hashimoto Disease, nervous system disorder, Dermatitis, Senile Plaques and Metabolic Diseases. The involved functions are known as 5-(carboxyamino)imidazole ribonucleotide mutase activity, Signal Transduction, Biochemical Pathway, Phosphorylation and MAP kinase kinase activity. Nobiletin often locates in Extracellular, Protoplasm, Back, Mouse Skin and Skin - Epidermis (MMHCC). The associated genes with Nobiletin are MAP2K1 gene, PTGS2 gene, Amyloid beta-Protein Precursor, Candidate Disease Gene and BCL2 gene. The related lipids are Lipopolysaccharides and Sterols. The related experimental models are Mouse Model and Transgenic Model. 550
LMPK12112009 LMPK12112009 is a lipid of Polyketides (PK) class. 216
morin morin is a lipid of Polyketides (PK) class. Morin is associated with abnormalities such as Colitis, Hyperuricemia, Gout, Parkinson Disease and Rheumatoid Arthritis. The involved functions are known as establishment and maintenance of localization, Binding (Molecular Function), Uptake, Increased Sensitivy and Cell Cycle Arrest. Morin often locates in Cell Wall, apoplast, Plasma membrane, Cytoplasmic matrix and Membrane. The associated genes with morin are GADD45A gene, MAPK8 gene, ODAM gene, TNFRSF1A gene and ALPP gene. The related lipids are Lipopolysaccharides, Butyrates, Fatty Acids, Nonesterified, Palmitates and Oleates. 1499
Quercetagetin Quercetagetin is a lipid of Polyketides (PK) class. The involved functions are known as inhibitors, Metabolic Inhibition and syncytium formation. Quercetagetin often locates in Tissue membrane. 97
isoliquiritigenin Isoliquiritigenin is a lipid of Polyketides (PK) class. Isoliquiritigenin is associated with abnormalities such as abnormal fragmented structure, Gastric ulcer, Gastric mucosa lesion, Peptic Ulcer and Wiskott-Aldrich Syndrome. The involved functions are known as Mass-to-Charge Ratio, Anabolism, Oxidation, inhibitors and Energy Absorption. Isoliquiritigenin often locates in Microsomes, Liver, Hepatic, Microsomes, Immune system and Vacuole. The associated genes with Isoliquiritigenin are P4HTM gene, BCL2 gene, AP1AR gene, oxytocin, 1-desamino-(O-Et-Tyr)(2)- and ODAM gene. The related experimental models are Knock-out. 220
butein Butein is a lipid of Polyketides (PK) class. Butein is associated with abnormalities such as Glomerulonephritis, Fibrosis, Liver, Kidney Failure, Acute, Mastocytosis and Chimera disorder. The involved functions are known as Phosphorylation, Transcription, Genetic, IkappaB kinase activity, Gene Expression and Signal Transduction. Butein often locates in Membrane, Cytoplasmic, IkappaB kinase complex, Protoplasm and Plasma membrane. The associated genes with Butein are ICAM1 gene, MAPK8 gene, MYC gene, BCL2 gene and BCL2L1 gene. The related lipids are Promega. The related experimental models are Xenograft Model, Knock-out and Mouse Model. 190
Xanthohumol Xanthohumol is a lipid of Polyketides (PK) class. Xanthohumol is associated with abnormalities such as Endometriosis, site unspecified, Cyst, peritoneal lesion, Proliferative inflammation and furuncle. The involved functions are known as Cell Proliferation, Signal Transduction, Pathologic Neovascularization, Adverse effects and Proliferation (morphologic abnormality). Xanthohumol often locates in peritoneal, Mesentery, Membrane, Tissue specimen from uterus and Cell Nucleus. The associated genes with Xanthohumol are PI3 gene, KEAP1 gene, SLC33A1 gene, BCR-ABL Fusion Gene and BIRC5 gene. The related lipids are Fatty Acids and Palmitates. The related experimental models are Knock-out. 465
licochalcone a licochalcone a is a lipid of Polyketides (PK) class. Licochalcone a is associated with abnormalities such as CLEFT LIP, CONGENITAL HEALED, Gastric ulcer, Keratoconjunctivitis Sicca, Inflammatory disorder and Leishmaniasis. The involved functions are known as 5-(carboxyamino)imidazole ribonucleotide mutase activity, Germination, Cell Growth, Metabolic Inhibition and Respiratory Chain. Licochalcone a often locates in Cell surface, Plasma membrane, IkappaB kinase complex, Mitochondria and Membrane. The associated genes with licochalcone a are HM13 gene, Salmine, cytochrome c'', TNFRSF1A gene and RIPK1 gene. The related lipids are Promega. 220
rottlerin Rottlerin is a lipid of Polyketides (PK) class. Rottlerin is associated with abnormalities such as PARAGANGLIOMAS 2, Hyperostosis, Diffuse Idiopathic Skeletal, Virus Diseases, Perisylvian syndrome and Autoimmune disease (systemic) NOS. The involved functions are known as Apoptosis, Regulation, Signal Transduction, inhibitors and Proteasome Inhibitors [MoA]. Rottlerin often locates in Clone, Membrane, Body tissue, Plasma membrane and soluble. The associated genes with Rottlerin are XIAP gene, GAPDH gene, ICAM1 gene, P4HTM gene and TNFSF10 gene. The related lipids are Promega, Fatty Acids, Sphingolipids, Lipopolysaccharides and Saponin. The related experimental models are Mouse Model, Xenograft Model and Cancer Model. 1198
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