MeSH term | MeSH ID | Detail |
---|---|---|
Thromboembolism | D013923 | 6 associated lipids |
Vitamin K Deficiency | D014813 | 5 associated lipids |
Exanthema | D005076 | 11 associated lipids |
Phylloquinone is a lipid of Prenol Lipids (PR) class. Phylloquinone is associated with abnormalities such as Vitamin K Deficiency, Malnutrition, Consumption-archaic term for TB, Osteoporosis and Hyperostosis, Diffuse Idiopathic Skeletal. The involved functions are known as Ingestion, Blood Circulation, Genetic Polymorphism, Intestinal Absorption and Process. Phylloquinone often locates in Blood, Body tissue, Hepatic, Membrane and Entire bony skeleton. The associated genes with phylloquinone are Vitamin K Epoxide Reductase Complex, Subunit 1, GGCX gene, CYP4F2 gene, Alleles and APOE gene. The related lipids are Micelles, 208-G, Fatty Acids, Total cholesterol and Sphingolipids. The related experimental models are Knock-out.
To understand associated biological information of phylloquinone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
phylloquinone is suspected in Vitamin K Deficiency, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, vitamin depletion, Malnutrition, Osteoporosis and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with phylloquinone
MeSH term | MeSH ID | Detail |
---|---|---|
Thromboembolism | D013923 | 6 associated lipids |
Vitamin K Deficiency | D014813 | 5 associated lipids |
Exanthema | D005076 | 11 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'A dedicated thioesterase of the Hotdog-fold family is required for the biosynthesis of the naphthoquinone ring of vitamin K1.' (Widhalm JR et al., 2009) and Knock-out are used in the study 'Deficiency in phylloquinone (vitamin K1) methylation affects prenyl quinone distribution, photosystem I abundance, and anthocyanin accumulation in the Arabidopsis AtmenG mutant.' (Lohmann A et al., 2006).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Wyskida K et al. | Functional deficiency of vitamin K in hemodialysis patients in Upper Silesia in Poland. | 2016 | Int Urol Nephrol | pmid:27000106 |
Clarke P et al. | Total and Differential Phylloquinone (Vitamin K1) Intakes of Preterm Infants from All Sources during the Neonatal Period. | 2015 | Nutrients | pmid:26426042 |
Chouet J et al. | Dietary Vitamin K Intake Is Associated with Cognition and Behaviour among Geriatric Patients: The CLIP Study. | 2015 | Nutrients | pmid:26274973 |
Orlando A et al. | Vitamin K1 exerts antiproliferative effects and induces apoptosis in three differently graded human colon cancer cell lines. | 2015 | Biomed Res Int | pmid:26075224 |
Fatihi A et al. | A Dedicated Type II NADPH Dehydrogenase Performs the Penultimate Step in the Biosynthesis of Vitamin K1 in Synechocystis and Arabidopsis. | 2015 | Plant Cell | pmid:26023160 |
Centi AJ et al. | Osteocalcin carboxylation is not associated with body weight or percent fat changes during weight loss in post-menopausal women. | 2015 | Endocrine | pmid:25963022 |
Makita H and Hastings G | Directionality of electron transfer in cyanobacterial photosystem I at 298 and 77K. | 2015 | FEBS Lett. | pmid:25962848 |
Ford PA et al. | Autologous Stem-Cell Transplantation Without Hematopoietic Support for the Treatment of Hematologic Malignancies in Jehovah's Witnesses. | 2015 | J. Clin. Oncol. | pmid:25870085 |
Rehder DS et al. | Gamma-carboxylation and fragmentation of osteocalcin in human serum defined by mass spectrometry. | 2015 | Mol. Cell Proteomics | pmid:25855755 |
Santabarbara S et al. | Controlling electron transfer between the two cofactor chains of photosystem I by the redox state of one of their components. | 2015 | Biophys. J. | pmid:25809266 |