| MeSH term | MeSH ID | Detail |
|---|---|---|
| Thromboembolism | D013923 | 6 associated lipids |
| Vitamin K Deficiency | D014813 | 5 associated lipids |
| Exanthema | D005076 | 11 associated lipids |
Total
3
phylloquinone
Phylloquinone is a lipid of Prenol Lipids (PR) class. Phylloquinone is associated with abnormalities such as Vitamin K Deficiency, Malnutrition, Consumption-archaic term for TB, Osteoporosis and Hyperostosis, Diffuse Idiopathic Skeletal. The involved functions are known as Ingestion, Blood Circulation, Genetic Polymorphism, Intestinal Absorption and Process. Phylloquinone often locates in Blood, Body tissue, Hepatic, Membrane and Entire bony skeleton. The associated genes with phylloquinone are Vitamin K Epoxide Reductase Complex, Subunit 1, GGCX gene, CYP4F2 gene, Alleles and APOE gene. The related lipids are Micelles, 208-G, Fatty Acids, Total cholesterol and Sphingolipids. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of phylloquinone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with phylloquinone?
phylloquinone is suspected in Vitamin K Deficiency, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, vitamin depletion, Malnutrition, Osteoporosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with phylloquinone
PubChem Associated disorders and diseases
What pathways are associated with phylloquinone
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with phylloquinone?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with phylloquinone?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with phylloquinone?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with phylloquinone?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with phylloquinone?
Knock-out
Knock-out are used in the study 'A dedicated thioesterase of the Hotdog-fold family is required for the biosynthesis of the naphthoquinone ring of vitamin K1.' (Widhalm JR et al., 2009) and Knock-out are used in the study 'Deficiency in phylloquinone (vitamin K1) methylation affects prenyl quinone distribution, photosystem I abundance, and anthocyanin accumulation in the Arabidopsis AtmenG mutant.' (Lohmann A et al., 2006).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with phylloquinone
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Jo JC et al. | Topical vitamin K1 may not be effective in preventing acneiform rash during cetuximab treatment in patients with metastatic colorectal cancer. | 2013 Jan-Feb | Eur J Dermatol | pmid:23238388 |
| Delmonte P et al. | Modifications ofAOAC Official Method 999.15 to improve the quantitation of vitamin K1 in complex formulated nutritional products. | 2013 Jan-Feb | J AOAC Int | pmid:23513963 |
| Musdal Y et al. | FDA-approved drugs and other compounds tested as inhibitors of human glutathione transferase P1-1. | 2013 | Chem. Biol. Interact. | pmid:23769903 |
| Marinova M et al. | VKORC1-dependent pharmacokinetics of intravenous and oral phylloquinone (vitamin K1) mixed micelles formulation. | 2013 | Eur. J. Clin. Pharmacol. | pmid:22864379 |
| Hirai K et al. | Influence of CYP4F2 polymorphisms and plasma vitamin K levels on warfarin sensitivity in Japanese pediatric patients. | 2013 | Drug Metab. Pharmacokinet. | pmid:22892446 |
| Ibrahim F et al. | Impact of co-administration of protonated nanostructured aluminum silicate (cholesterol absorption inhibitor) on the absorption of lipid soluble vitamins D3 and K1: an assessment of pharmacokinetic and in vitro intraluminal processing. | 2013 | Eur J Pharm Sci | pmid:23454011 |
| Thom N et al. | Nonuraemic nonfatal idiopathic calciphylaxis in a kitten. | 2013 | Vet. Dermatol. | pmid:23930985 |
| Majeed H et al. | Effect of 200μG/day of vitamin K1 on the variability of anticoagulation control in patients on warfarin: a randomized controlled trial. | 2013 | Thromb. Res. | pmid:23953594 |
| Haraikawa M et al. | Effects of gamma-glutamyl carboxylase gene polymorphism (R325Q) on the association between dietary vitamin K intake and gamma-carboxylation of osteocalcin in young adults. | 2013 | Asia Pac J Clin Nutr | pmid:24231026 |
| Wahlqvist ML et al. | Clinical decision-making for vitamin K-1 and K-2 deficiency and coronary artery calcification with warfarin therapy: are diet, factor Xa inhibitors or both the answer? | 2013 | Asia Pac J Clin Nutr | pmid:24066371 |