MeSH term | MeSH ID | Detail |
---|---|---|
Thromboembolism | D013923 | 6 associated lipids |
Vitamin K Deficiency | D014813 | 5 associated lipids |
Exanthema | D005076 | 11 associated lipids |
Phylloquinone is a lipid of Prenol Lipids (PR) class. Phylloquinone is associated with abnormalities such as Vitamin K Deficiency, Malnutrition, Consumption-archaic term for TB, Osteoporosis and Hyperostosis, Diffuse Idiopathic Skeletal. The involved functions are known as Ingestion, Blood Circulation, Genetic Polymorphism, Intestinal Absorption and Process. Phylloquinone often locates in Blood, Body tissue, Hepatic, Membrane and Entire bony skeleton. The associated genes with phylloquinone are Vitamin K Epoxide Reductase Complex, Subunit 1, GGCX gene, CYP4F2 gene, Alleles and APOE gene. The related lipids are Micelles, 208-G, Fatty Acids, Total cholesterol and Sphingolipids. The related experimental models are Knock-out.
To understand associated biological information of phylloquinone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
phylloquinone is suspected in Vitamin K Deficiency, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, vitamin depletion, Malnutrition, Osteoporosis and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with phylloquinone
MeSH term | MeSH ID | Detail |
---|---|---|
Thromboembolism | D013923 | 6 associated lipids |
Vitamin K Deficiency | D014813 | 5 associated lipids |
Exanthema | D005076 | 11 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
Knock-out are used in the study 'A dedicated thioesterase of the Hotdog-fold family is required for the biosynthesis of the naphthoquinone ring of vitamin K1.' (Widhalm JR et al., 2009) and Knock-out are used in the study 'Deficiency in phylloquinone (vitamin K1) methylation affects prenyl quinone distribution, photosystem I abundance, and anthocyanin accumulation in the Arabidopsis AtmenG mutant.' (Lohmann A et al., 2006).
Model | Cross reference | Weighted score | Related literatures |
---|
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Santabarbara S et al. | Controlling electron transfer between the two cofactor chains of photosystem I by the redox state of one of their components. | 2015 | Biophys. J. | pmid:25809266 |
Shea MK et al. | The association between vitamin K status and knee osteoarthritis features in older adults: the Health, Aging and Body Composition Study. | 2015 | Osteoarthr. Cartil. | pmid:25528106 |
Lin T et al. | Periprocedural anticoagulation of patients undergoing pericardiocentesis for cardiac tamponade complicating catheter ablation of atrial fibrillation. | 2015 | Int Heart J | pmid:25503659 |
Champion S et al. | Vitamin K1 antagonisation is not safe in high thromboembolic risk patients with over-anticoagulation. | 2014 May-Jun | Therapie | pmid:24901290 |
Hemmati AA et al. | Topical vitamin K1 promotes repair of full thickness wound in rat. | 2014 Jul-Aug | Indian J Pharmacol | pmid:25097279 |
Chao MT et al. | An innovative acupuncture treatment for primary dysmenorrhea: a randomized, crossover pilot study. | 2014 Jan-Feb | Altern Ther Health Med | pmid:24445356 |
Kozuleva MA et al. | O2 reduction by photosystem I involves phylloquinone under steady-state illumination. | 2014 | FEBS Lett. | pmid:25311539 |
van Rein N et al. | Vitamin K1 in oral solution or tablets: a crossover trial and two randomized controlled trials to compare effects. | 2014 | J. Thromb. Haemost. | pmid:25308231 |
Pinta F et al. | Pilot clinical trial on the efficacy of prophylactic use of vitamin K1-based cream (Vigorskin) to prevent cetuximab-induced skin rash in patients with metastatic colorectal cancer. | 2014 | Clin Colorectal Cancer | pmid:24332355 |
Campani V et al. | Development of a liposome-based formulation for vitamin K1 nebulization on the skin. | 2014 | Int J Nanomedicine | pmid:24748792 |