phylloquinone

Phylloquinone is a lipid of Prenol Lipids (PR) class. Phylloquinone is associated with abnormalities such as Vitamin K Deficiency, Malnutrition, Consumption-archaic term for TB, Osteoporosis and Hyperostosis, Diffuse Idiopathic Skeletal. The involved functions are known as Ingestion, Blood Circulation, Genetic Polymorphism, Intestinal Absorption and Process. Phylloquinone often locates in Blood, Body tissue, Hepatic, Membrane and Entire bony skeleton. The associated genes with phylloquinone are Vitamin K Epoxide Reductase Complex, Subunit 1, GGCX gene, CYP4F2 gene, Alleles and APOE gene. The related lipids are Micelles, 208-G, Fatty Acids, Total cholesterol and Sphingolipids. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of phylloquinone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with phylloquinone?

phylloquinone is suspected in Vitamin K Deficiency, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, vitamin depletion, Malnutrition, Osteoporosis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with phylloquinone

MeSH term MeSH ID Detail
Thromboembolism D013923 6 associated lipids
Vitamin K Deficiency D014813 5 associated lipids
Exanthema D005076 11 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with phylloquinone

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with phylloquinone?

Related references are published most in these journals:

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What functions are associated with phylloquinone?


Related references are published most in these journals:

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What lipids are associated with phylloquinone?

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What genes are associated with phylloquinone?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with phylloquinone?

Knock-out

Knock-out are used in the study 'A dedicated thioesterase of the Hotdog-fold family is required for the biosynthesis of the naphthoquinone ring of vitamin K1.' (Widhalm JR et al., 2009) and Knock-out are used in the study 'Deficiency in phylloquinone (vitamin K1) methylation affects prenyl quinone distribution, photosystem I abundance, and anthocyanin accumulation in the Arabidopsis AtmenG mutant.' (Lohmann A et al., 2006).

Related references are published most in these journals:

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NCBI Entrez Crosslinks

All references with phylloquinone

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Authors Title Published Journal PubMed Link
Amaral ME et al. Effect of vitamin K1 supplementation on left colon healing in rats with extrahepatic biliary obstruction. 2014 Acta Cir Bras pmid:25140594
Farley SM et al. Deuterium-labeled phylloquinone fed to α-tocopherol-injected rats demonstrates sensitivity of low phylloquinone-containing tissues to menaquinone-4 depletion. 2014 Mol Nutr Food Res pmid:25044667
Chao MT et al. Increase in plasma phylloquinone concentrations following acupoint injection for the treatment of primary dysmenorrhea. 2014 J Acupunct Meridian Stud pmid:24929459
Shea MK et al. Associations between vitamin K status and haemostatic and inflammatory biomarkers in community-dwelling adults. The Multi-Ethnic Study of Atherosclerosis. 2014 Thromb. Haemost. pmid:24849546
Mi YN et al. The severe adverse reaction to vitamin k1 injection is anaphylactoid reaction but not anaphylaxis. 2014 PLoS ONE pmid:24594861
Caluwé R et al. Vitamin K2 supplementation in haemodialysis patients: a randomized dose-finding study. 2014 Nephrol. Dial. Transplant. pmid:24285428
Dalmeijer GW et al. Phylloquinone concentrations and the risk of vascular calcification in healthy women. 2014 Arterioscler. Thromb. Vasc. Biol. pmid:24855054
Milanovsky GE et al. Molecular dynamics study of the primary charge separation reactions in Photosystem I: effect of the replacement of the axial ligands to the electron acceptor Aâ‚€. 2014 Biochim. Biophys. Acta pmid:24637178
Rødbotten R et al. Vitamin K2 in different bovine muscles and breeds. 2014 Meat Sci. pmid:24508562
El-Shabrawi MH and Farrag MI Hepatic manifestations in juvenile systemic lupus erythematosus. 2014 Recent Pat Inflamm Allergy Drug Discov pmid:24383439