phylloquinone

Phylloquinone is a lipid of Prenol Lipids (PR) class. Phylloquinone is associated with abnormalities such as Vitamin K Deficiency, Malnutrition, Consumption-archaic term for TB, Osteoporosis and Hyperostosis, Diffuse Idiopathic Skeletal. The involved functions are known as Ingestion, Blood Circulation, Genetic Polymorphism, Intestinal Absorption and Process. Phylloquinone often locates in Blood, Body tissue, Hepatic, Membrane and Entire bony skeleton. The associated genes with phylloquinone are Vitamin K Epoxide Reductase Complex, Subunit 1, GGCX gene, CYP4F2 gene, Alleles and APOE gene. The related lipids are Micelles, 208-G, Fatty Acids, Total cholesterol and Sphingolipids. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of phylloquinone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with phylloquinone?

phylloquinone is suspected in Vitamin K Deficiency, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, vitamin depletion, Malnutrition, Osteoporosis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with phylloquinone

MeSH term MeSH ID Detail
Thromboembolism D013923 6 associated lipids
Vitamin K Deficiency D014813 5 associated lipids
Exanthema D005076 11 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with phylloquinone

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with phylloquinone?

Related references are published most in these journals:

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What functions are associated with phylloquinone?


Related references are published most in these journals:

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What lipids are associated with phylloquinone?

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What genes are associated with phylloquinone?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with phylloquinone?

Knock-out

Knock-out are used in the study 'A dedicated thioesterase of the Hotdog-fold family is required for the biosynthesis of the naphthoquinone ring of vitamin K1.' (Widhalm JR et al., 2009) and Knock-out are used in the study 'Deficiency in phylloquinone (vitamin K1) methylation affects prenyl quinone distribution, photosystem I abundance, and anthocyanin accumulation in the Arabidopsis AtmenG mutant.' (Lohmann A et al., 2006).

Related references are published most in these journals:

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NCBI Entrez Crosslinks

All references with phylloquinone

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Authors Title Published Journal PubMed Link
Kopec RE et al. Comparison of high-performance liquid chromatography/tandem mass spectrometry and high-performance liquid chromatography/photo-diode array detection for the quantitation of carotenoids, retinyl esters, α-tocopherol and phylloquinone in chylomicron-rich fractions of human plasma. 2013 Rapid Commun. Mass Spectrom. pmid:23681818
Martinis J et al. A chloroplast ABC1-like kinase regulates vitamin E metabolism in Arabidopsis. 2013 Plant Physiol. pmid:23632854
Crăciun AM and Vermeer C Apolipoprotein E genotype may influence urinary gammacarboxyglutamate (Gla) concentrations in young individuals. 2013 Gen. Physiol. Biophys. pmid:23817635
Plank RM et al. Vitamin K deficiency bleeding and early infant male circumcision in Africa. 2013 Obstet Gynecol pmid:23884276
Reumann S Biosynthesis of vitamin K1 (phylloquinone) by plant peroxisomes and its integration into signaling molecule synthesis pathways. 2013 Subcell. Biochem. pmid:23821151
Lovern D and Marbois B Does menaquinone participate in brain astrocyte electron transport? 2013 Med. Hypotheses pmid:23910074
Krüger T et al. Warfarin induces cardiovascular damage in mice. 2013 Arterioscler. Thromb. Vasc. Biol. pmid:23990204
Meineke I et al. Routine micromethod for the determination of vitamin K1 in human plasma. 2013 Ther Drug Monit pmid:24089072
Hanzawa F et al. Dietary sesame seed and its lignan, sesamin, increase tocopherol and phylloquinone concentrations in male rats. 2013 J. Nutr. pmid:23700348
Wehler TC et al. Cetuximab-induced skin exanthema: prophylactic and reactive skin therapy are equally effective. 2013 J. Cancer Res. Clin. Oncol. pmid:23918349