MeSH term | MeSH ID | Detail |
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Epilepsy, Absence | D004832 | 5 associated lipids |
Tetrahydrodeoxycorticosterone is a lipid of Sterol Lipids (ST) class. Tetrahydrodeoxycorticosterone is associated with abnormalities such as Cerebrovascular accident, Epilepsy, Status Epilepticus, Still and Liver diseases. The involved functions are known as Chromosome Pairing, Adjudication, inhibitors, Neuronal Transmission and Synthesis. Tetrahydrodeoxycorticosterone often locates in Entire oral cavity, Body tissue, Pole, Brain region and Cell surface. The associated genes with Tetrahydrodeoxycorticosterone are ADRBK1 gene. The related lipids are pregnane-20-one, allotetrahydrodeoxycorticosterone, Steroids, 17-phenylandrost-16-en-3-ol and pregnenolone sulfate. The related experimental models are Transgenic Model.
To understand associated biological information of Tetrahydrodeoxycorticosterone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Tetrahydrodeoxycorticosterone is suspected in Cerebrovascular accident, Epilepsy, Hepatic Encephalopathy, Status Epilepticus, Liver diseases, Convulsions and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Tetrahydrodeoxycorticosterone
MeSH term | MeSH ID | Detail |
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Epilepsy, Absence | D004832 | 5 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Transgenic Model are used in the study 'GABAA receptor modulating steroid antagonists (GAMSA) are functional in vivo.' (Johansson M et al., 2016).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Wongsamitkul N et al. | Toward Understanding Functional Properties and Subunit Arrangement of α4β2δ γ-Aminobutyric Acid, Type A (GABAA) Receptors. | 2016 | J. Biol. Chem. | pmid:27382064 |
Wilkins ME et al. | Murine startle mutant Nmf11 affects the structural stability of the glycine receptor and increases deactivation. | 2016 | J. Physiol. (Lond.) | pmid:27028707 |
Johansson M et al. | GABAA receptor modulating steroid antagonists (GAMSA) are functional in vivo. | 2016 | J. Steroid Biochem. Mol. Biol. | pmid:26523675 |
Johansson M et al. | GR3027 antagonizes GABAA receptor-potentiating neurosteroids and restores spatial learning and motor coordination in rats with chronic hyperammonemia and hepatic encephalopathy. | 2015 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:26138462 |
Villumsen IS et al. | Pharmacological characterisation of murine α4β1δ GABAA receptors expressed in Xenopus oocytes. | 2015 | BMC Neurosci | pmid:25887256 |
Shiri Z et al. | Neurosteroidal modulation of in vitro epileptiform activity is enhanced in pilocarpine-treated epileptic rats. | 2015 | Neurobiol. Dis. | pmid:25814046 |
Herrington R et al. | Neurosteroids differentially modulate fast and slow interictal discharges in the hippocampal CA3 area. | 2015 | Eur. J. Neurosci. | pmid:25471484 |
Adams JM et al. | Modulation of neurosteroid potentiation by protein kinases at synaptic- and extrasynaptic-type GABAA receptors. | 2015 | Neuropharmacology | pmid:25278033 |
Marowsky A and Vogt KE | Delta-subunit-containing GABAA-receptors mediate tonic inhibition in paracapsular cells of the mouse amygdala. | 2014 | Front Neural Circuits | pmid:24723854 |
Kerti-Szigeti K et al. | Synaptic GABAA receptor clustering without the γ2 subunit. | 2014 | J. Neurosci. | pmid:25080584 |