| MeSH term | MeSH ID | Detail |
|---|---|---|
| Epilepsy, Absence | D004832 | 5 associated lipids |
Total
1
Tetrahydrodeoxycorticosterone
Tetrahydrodeoxycorticosterone is a lipid of Sterol Lipids (ST) class. Tetrahydrodeoxycorticosterone is associated with abnormalities such as Cerebrovascular accident, Epilepsy, Status Epilepticus, Still and Liver diseases. The involved functions are known as Chromosome Pairing, Adjudication, inhibitors, Neuronal Transmission and Synthesis. Tetrahydrodeoxycorticosterone often locates in Entire oral cavity, Body tissue, Pole, Brain region and Cell surface. The associated genes with Tetrahydrodeoxycorticosterone are ADRBK1 gene. The related lipids are pregnane-20-one, allotetrahydrodeoxycorticosterone, Steroids, 17-phenylandrost-16-en-3-ol and pregnenolone sulfate. The related experimental models are Transgenic Model.
Cross Reference
Introduction
To understand associated biological information of Tetrahydrodeoxycorticosterone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Tetrahydrodeoxycorticosterone?
Tetrahydrodeoxycorticosterone is suspected in Cerebrovascular accident, Epilepsy, Hepatic Encephalopathy, Status Epilepticus, Liver diseases, Convulsions and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Tetrahydrodeoxycorticosterone
PubChem Associated disorders and diseases
What pathways are associated with Tetrahydrodeoxycorticosterone
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Tetrahydrodeoxycorticosterone?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Am. J. Physiol. Gastrointest. Liver Physiol. (1)
- J. Biol. Chem. (1)
- J. Steroid Biochem. Mol. Biol. (1)
- Others (2)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Tetrahydrodeoxycorticosterone?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Tetrahydrodeoxycorticosterone?
Related references are published most in these journals:
- Am. J. Physiol. Gastrointest. Liver Physiol. (1)
- J. Steroid Biochem. Mol. Biol. (1)
- Neurobiol. Dis. (1)
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Tetrahydrodeoxycorticosterone?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Tetrahydrodeoxycorticosterone?
Transgenic Model
Transgenic Model are used in the study 'GABAA receptor modulating steroid antagonists (GAMSA) are functional in vivo.' (Johansson M et al., 2016).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Tetrahydrodeoxycorticosterone
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Jiang R et al. | Retrochalcone derivatives are positive allosteric modulators at synaptic and extrasynaptic GABA(A) receptors in vitro. | 2011 | Br. J. Pharmacol. | pmid:21133889 |
| Maksay G and Fodor L | Differential effects of two major neurosteroids on cerebellar and cortical GABA(A) receptor binding and function. | 2011 | Eur. J. Pharmacol. | pmid:20951124 |
| Morgan ML et al. | Neuroactive steroids after estrogen exposure in depressed postmenopausal women treated with sertraline and asymptomatic postmenopausal women. | 2010 | Arch Womens Ment Health | pmid:19728035 |
| Chang JL et al. | Acute neurosteroids inhibit the spinal reflex potentiation via GABAergic neurotransmission. | 2010 | Am. J. Physiol. Renal Physiol. | pmid:20357028 |
| Frye CA et al. | Mnemonic effects of progesterone to mice require formation of 3alpha,5alpha-THP. | 2010 | Neuroreport | pmid:20431492 |
| Chen X et al. | Homeostatic regulation of synaptic excitability: tonic GABA(A) receptor currents replace I(h) in cortical pyramidal neurons of HCN1 knock-out mice. | 2010 | J. Neurosci. | pmid:20164346 |
| Baker C et al. | Multiple roles for the first transmembrane domain of GABAA receptor subunits in neurosteroid modulation and spontaneous channel activity. | 2010 | Neurosci. Lett. | pmid:20193738 |
| Porcu P et al. | Differential effects of ethanol on serum GABAergic 3alpha,5alpha/3alpha,5beta neuroactive steroids in mice, rats, cynomolgus monkeys, and humans. | 2010 | Alcohol. Clin. Exp. Res. | pmid:20028362 |
| Ramakrishnan L and Hess GP | Mechanism of potentiation of a dysfunctional epilepsy-linked mutated GABA(A) receptor by a neurosteroid (3alpha, 21-dihydroxy-5alpha-pregnan-20-one): transient kinetic investigations. | 2010 | Biochemistry | pmid:20726514 |
| Frye CA et al. | Conjugated equine estrogen, with medroxyprogesterone acetate, enhances formation of 5alpha-reduced progestogens and reduces anxiety-like behavior of middle-aged rats. | 2010 | Behav Pharmacol | pmid:20679892 |