MeSH term | MeSH ID | Detail |
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Epilepsy, Absence | D004832 | 5 associated lipids |
Tetrahydrodeoxycorticosterone is a lipid of Sterol Lipids (ST) class. Tetrahydrodeoxycorticosterone is associated with abnormalities such as Cerebrovascular accident, Epilepsy, Status Epilepticus, Still and Liver diseases. The involved functions are known as Chromosome Pairing, Adjudication, inhibitors, Neuronal Transmission and Synthesis. Tetrahydrodeoxycorticosterone often locates in Entire oral cavity, Body tissue, Pole, Brain region and Cell surface. The associated genes with Tetrahydrodeoxycorticosterone are ADRBK1 gene. The related lipids are pregnane-20-one, allotetrahydrodeoxycorticosterone, Steroids, 17-phenylandrost-16-en-3-ol and pregnenolone sulfate. The related experimental models are Transgenic Model.
To understand associated biological information of Tetrahydrodeoxycorticosterone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Tetrahydrodeoxycorticosterone is suspected in Cerebrovascular accident, Epilepsy, Hepatic Encephalopathy, Status Epilepticus, Liver diseases, Convulsions and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Tetrahydrodeoxycorticosterone
MeSH term | MeSH ID | Detail |
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Epilepsy, Absence | D004832 | 5 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Transgenic Model are used in the study 'GABAA receptor modulating steroid antagonists (GAMSA) are functional in vivo.' (Johansson M et al., 2016).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Morgan ML et al. | Neuroactive steroids after estrogen exposure in depressed postmenopausal women treated with sertraline and asymptomatic postmenopausal women. | 2010 | Arch Womens Ment Health | pmid:19728035 |
Porcu P et al. | Differential effects of ethanol on serum GABAergic 3alpha,5alpha/3alpha,5beta neuroactive steroids in mice, rats, cynomolgus monkeys, and humans. | 2010 | Alcohol. Clin. Exp. Res. | pmid:20028362 |
Baur R et al. | Structure of alpha6 beta3 delta GABA(A) receptors and their lack of ethanol sensitivity. | 2009 | J. Neurochem. | pmid:19765192 |
Kaur KH et al. | Unanticipated structural and functional properties of delta-subunit-containing GABAA receptors. | 2009 | J. Biol. Chem. | pmid:19141615 |
Zwanzger P et al. | Changes in CCK-4 induced panic after treatment with the GABA-reuptake inhibitor tiagabine are associated with an increase in 3alpha,5alpha-tetrahydrodeoxycorticosterone concentrations. | 2009 | Psychoneuroendocrinology | pmid:19501468 |
Frye CA and Paris JJ | Infusions of bicuculline to the ventral tegmental area attenuates sexual, exploratory, and anti-anxiety behavior of proestrous rats. | 2009 | Pharmacol. Biochem. Behav. | pmid:19576238 |
Kondo D et al. | Peripheral-type benzodiazepine receptor antagonist is effective in relieving neuropathic pain in mice. | 2009 | J. Pharmacol. Sci. | pmid:19403993 |
Codocedo JF et al. | Neurosteroids differentially modulate P2X ATP-gated channels through non-genomic interactions. | 2009 | J. Neurochem. | pmid:19457083 |
Meera P et al. | Etomidate, propofol and the neurosteroid THDOC increase the GABA efficacy of recombinant alpha4beta3delta and alpha4beta3 GABA A receptors expressed in HEK cells. | 2009 | Neuropharmacology | pmid:18778723 |
Hosie AM et al. | Conserved site for neurosteroid modulation of GABA A receptors. | 2009 | Neuropharmacology | pmid:18762201 |