MeSH term | MeSH ID | Detail |
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Epilepsy, Absence | D004832 | 5 associated lipids |
Tetrahydrodeoxycorticosterone is a lipid of Sterol Lipids (ST) class. Tetrahydrodeoxycorticosterone is associated with abnormalities such as Cerebrovascular accident, Epilepsy, Status Epilepticus, Still and Liver diseases. The involved functions are known as Chromosome Pairing, Adjudication, inhibitors, Neuronal Transmission and Synthesis. Tetrahydrodeoxycorticosterone often locates in Entire oral cavity, Body tissue, Pole, Brain region and Cell surface. The associated genes with Tetrahydrodeoxycorticosterone are ADRBK1 gene. The related lipids are pregnane-20-one, allotetrahydrodeoxycorticosterone, Steroids, 17-phenylandrost-16-en-3-ol and pregnenolone sulfate. The related experimental models are Transgenic Model.
To understand associated biological information of Tetrahydrodeoxycorticosterone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Tetrahydrodeoxycorticosterone is suspected in Cerebrovascular accident, Epilepsy, Hepatic Encephalopathy, Status Epilepticus, Liver diseases, Convulsions and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Tetrahydrodeoxycorticosterone
MeSH term | MeSH ID | Detail |
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Epilepsy, Absence | D004832 | 5 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Transgenic Model are used in the study 'GABAA receptor modulating steroid antagonists (GAMSA) are functional in vivo.' (Johansson M et al., 2016).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Wang L et al. | Tonic GABAergic inhibition of sympathetic preganglionic neurons: a novel substrate for sympathetic control. | 2008 | J. Neurosci. | pmid:19020037 |
Ahboucha S et al. | Indomethacin improves locomotor deficit and reduces brain concentrations of neuroinhibitory steroids in rats following portacaval anastomosis. | 2008 | Neurogastroenterol. Motil. | pmid:18482252 |
Vardya I et al. | Cell type-specific GABA A receptor-mediated tonic inhibition in mouse neocortex. | 2008 | J. Neurophysiol. | pmid:18463187 |
Han SM and Youn DH | GABAA receptor-mediated tonic currents in substantia gelatinosa neurons of rat spinal trigeminal nucleus pars caudalis. | 2008 | Neurosci. Lett. | pmid:18585436 |
Frye CA et al. | Exploratory, anti-anxiety, social, and sexual behaviors of rats in behavioral estrus is attenuated with inhibition of 3alpha,5alpha-THP formation in the midbrain ventral tegmental area. | 2008 | Behav. Brain Res. | pmid:18590775 |
Pisu MG et al. | Neuroactive steroids and GABAA receptor plasticity in the brain of the WAG/Rij rat, a model of absence epilepsy. | 2008 | J. Neurochem. | pmid:18624910 |
Zheleznova N et al. | alpha1beta2delta, a silent GABAA receptor: recruitment by tracazolate and neurosteroids. | 2008 | Br. J. Pharmacol. | pmid:18204487 |
Tuveri A et al. | Reduced serum level of THDOC, an anticonvulsant steroid, in women with perimenstrual catamenial epilepsy. | 2008 | Epilepsia | pmid:18325018 |
Frye CA et al. | Estrogen is necessary for 5alpha-pregnan-3alpha-ol-20-one (3alpha,5alpha-THP) infusion to the ventral tegmental area to facilitate social and sexual, but neither exploratory nor affective behavior of ovariectomized rats. | 2008 | Pharmacol. Biochem. Behav. | pmid:18786558 |
Frye CA and Walf AA | In the ventral tegmental area, progestogens' membrane-mediated actions for lordosis of rats involve the second-messenger phospholipase C. | 2008 | Brain Res. | pmid:18671954 |