Tetrahydrodeoxycorticosterone

Tetrahydrodeoxycorticosterone is a lipid of Sterol Lipids (ST) class. Tetrahydrodeoxycorticosterone is associated with abnormalities such as Cerebrovascular accident, Epilepsy, Status Epilepticus, Still and Liver diseases. The involved functions are known as Chromosome Pairing, Adjudication, inhibitors, Neuronal Transmission and Synthesis. Tetrahydrodeoxycorticosterone often locates in Entire oral cavity, Body tissue, Pole, Brain region and Cell surface. The associated genes with Tetrahydrodeoxycorticosterone are ADRBK1 gene. The related lipids are pregnane-20-one, allotetrahydrodeoxycorticosterone, Steroids, 17-phenylandrost-16-en-3-ol and pregnenolone sulfate. The related experimental models are Transgenic Model.

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Introduction

To understand associated biological information of Tetrahydrodeoxycorticosterone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tetrahydrodeoxycorticosterone?

Tetrahydrodeoxycorticosterone is suspected in Cerebrovascular accident, Epilepsy, Hepatic Encephalopathy, Status Epilepticus, Liver diseases, Convulsions and other diseases in descending order of the highest number of associated sentences.

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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tetrahydrodeoxycorticosterone

MeSH term MeSH ID Detail
Epilepsy, Absence D004832 5 associated lipids
Total 1

PubChem Associated disorders and diseases

What pathways are associated with Tetrahydrodeoxycorticosterone

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tetrahydrodeoxycorticosterone?

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What functions are associated with Tetrahydrodeoxycorticosterone?


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What lipids are associated with Tetrahydrodeoxycorticosterone?

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What genes are associated with Tetrahydrodeoxycorticosterone?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tetrahydrodeoxycorticosterone?

Transgenic Model

Transgenic Model are used in the study 'GABAA receptor modulating steroid antagonists (GAMSA) are functional in vivo.' (Johansson M et al., 2016).

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NCBI Entrez Crosslinks

All references with Tetrahydrodeoxycorticosterone

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Authors Title Published Journal PubMed Link
Eaton MM et al. Modulation of the human ρ1 GABAA receptor by inhibitory steroids. 2014 Psychopharmacology (Berl.) pmid:24317445
Herrington R et al. Neurosteroids modulate epileptiform activity and associated high-frequency oscillations in the piriform cortex. 2014 Neuroscience pmid:24157930
Carver CM and Reddy DS Neurosteroid interactions with synaptic and extrasynaptic GABA(A) receptors: regulation of subunit plasticity, phasic and tonic inhibition, and neuronal network excitability. 2013 Psychopharmacology (Berl.) pmid:24071826
Jang HJ et al. Layer- and cell-type-specific tonic GABAergic inhibition of pyramidal neurons in the rat visual cortex. 2013 Pflugers Arch. pmid:23812164
McQuarrie EP et al. Urinary corticosteroid excretion predicts left ventricular mass and proteinuria in chronic kidney disease. 2012 Clin. Sci. pmid:22397469
Kia A et al. Kindling alters neurosteroid-induced modulation of phasic and tonic GABAA receptor-mediated currents: role of phosphorylation. 2011 J. Neurochem. pmid:21175618
Jiang R et al. Retrochalcone derivatives are positive allosteric modulators at synaptic and extrasynaptic GABA(A) receptors in vitro. 2011 Br. J. Pharmacol. pmid:21133889
Sarkar J et al. Neurosteroidogenesis is required for the physiological response to stress: role of neurosteroid-sensitive GABAA receptors. 2011 J. Neurosci. pmid:22171026
Jo JY et al. Neurosteroid modulation of benzodiazepine-sensitive GABAA tonic inhibition in supraoptic magnocellular neurons. 2011 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:21451144
Bonin RP et al. Pharmacological enhancement of δ-subunit-containing GABA(A) receptors that generate a tonic inhibitory conductance in spinal neurons attenuates acute nociception in mice. 2011 Pain pmid:21396779