G(M3) Ganglioside

G(M3) Ganglioside is a lipid of Sphingolipids (SP) class. G(m3) ganglioside is associated with abnormalities such as Metabolic Diseases, Nodular glomerulosclerosis, Renal glomerular disease, Diabetes Mellitus and Hyperglycemia. The involved functions are known as Drug Interactions, Signal Transduction, Down-Regulation, Detergents and Ligand Binding. G(m3) ganglioside often locates in Tissue membrane, Body tissue, Cell surface, Membrane and Extracellular Matrix. The associated genes with G(M3) Ganglioside are PTPN11 gene, anti-IgM, Homologous Gene, SCAP2 gene and N-dodecyl-L-lysine amide. The related lipids are de-N-acetylneuraminyllactosylceramide, Membrane Lipids, Sphingolipids, stearic acid and sialogangliosides.

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Introduction

To understand associated biological information of G(M3) Ganglioside, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with G(M3) Ganglioside?

G(M3) Ganglioside is suspected in Renal glomerular disease, Sandhoff Disease, Nodular glomerulosclerosis, Diabetic Nephropathy, Diabetes, Fatty Streak, Arterial and other diseases in descending order of the highest number of associated sentences.

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No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with G(M3) Ganglioside

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with G(M3) Ganglioside?

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What functions are associated with G(M3) Ganglioside?


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What lipids are associated with G(M3) Ganglioside?

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What genes are associated with G(M3) Ganglioside?

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Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with G(M3) Ganglioside?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with G(M3) Ganglioside

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Authors Title Published Journal PubMed Link
Grey M et al. Acceleration of α-synuclein aggregation by exosomes. 2015 J. Biol. Chem. pmid:25425650
Margheri F et al. Differential uPAR recruitment in caveolar-lipid rafts by GM1 and GM3 gangliosides regulates endothelial progenitor cells angiogenesis. 2015 J. Cell. Mol. Med. pmid:25313007
DeMarco ML Molecular dynamics simulations of membrane- and protein-bound glycolipids using GLYCAM. 2015 Methods Mol. Biol. pmid:25753721
Yoshikawa M et al. Ganglioside GM3 is essential for the structural integrity and function of cochlear hair cells. 2015 Hum. Mol. Genet. pmid:25652401
Martinez-Martin N et al. Herpes simplex virus enhances chemokine function through modulation of receptor trafficking and oligomerization. 2015 Nat Commun pmid:25625471
Hakomori SI and Handa K GM3 and cancer. 2015 Glycoconj. J. pmid:25613425
Li Y et al. Ganglioside GM3 exerts opposite effects on motility via epidermal growth factor receptor and hepatocyte growth factor receptor-mediated migration signaling. 2015 Mol Med Rep pmid:25503644
Hernández AM and Vázquez AM Racotumomab-alum vaccine for the treatment of non-small-cell lung cancer. 2015 Expert Rev Vaccines pmid:25420897
Torbidoni AV et al. Immunoreactivity of the 14F7 Mab raised against N-Glycolyl GM3 Ganglioside in retinoblastoma tumours. 2015 Acta Ophthalmol pmid:25403557
Nagafuku M et al. Control of homeostatic and pathogenic balance in adipose tissue by ganglioside GM3. 2015 Glycobiology pmid:25303960