G(M3) Ganglioside

G(M3) Ganglioside is a lipid of Sphingolipids (SP) class. G(m3) ganglioside is associated with abnormalities such as Metabolic Diseases, Nodular glomerulosclerosis, Renal glomerular disease, Diabetes Mellitus and Hyperglycemia. The involved functions are known as Drug Interactions, Signal Transduction, Down-Regulation, Detergents and Ligand Binding. G(m3) ganglioside often locates in Tissue membrane, Body tissue, Cell surface, Membrane and Extracellular Matrix. The associated genes with G(M3) Ganglioside are PTPN11 gene, anti-IgM, Homologous Gene, SCAP2 gene and N-dodecyl-L-lysine amide. The related lipids are de-N-acetylneuraminyllactosylceramide, Membrane Lipids, Sphingolipids, stearic acid and sialogangliosides.

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Introduction

To understand associated biological information of G(M3) Ganglioside, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with G(M3) Ganglioside?

G(M3) Ganglioside is suspected in Renal glomerular disease, Sandhoff Disease, Nodular glomerulosclerosis, Diabetic Nephropathy, Diabetes, Fatty Streak, Arterial and other diseases in descending order of the highest number of associated sentences.

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No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with G(M3) Ganglioside

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with G(M3) Ganglioside?

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What functions are associated with G(M3) Ganglioside?


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What lipids are associated with G(M3) Ganglioside?

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What genes are associated with G(M3) Ganglioside?

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Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with G(M3) Ganglioside?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with G(M3) Ganglioside

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Authors Title Published Journal PubMed Link
Caughlin S et al. Increased Expression of Simple Ganglioside Species GM2 and GM3 Detected by MALDI Imaging Mass Spectrometry in a Combined Rat Model of Aβ Toxicity and Stroke. 2015 PLoS ONE pmid:26086081
Miklavcic JJ et al. Increased catabolism and decreased unsaturation of ganglioside in patients with inflammatory bowel disease. 2015 World J. Gastroenterol. pmid:26401073
Lipina C and Hundal HS Ganglioside GM3 as a gatekeeper of obesity-associated insulin resistance: Evidence and mechanisms. 2015 FEBS Lett. pmid:26434718
Saariaho AH et al. Autoantibodies against ganglioside GM3 are associated with narcolepsy-cataplexy developing after Pandemrix vaccination against 2009 pandemic H1N1 type influenza virus. 2015 J. Autoimmun. pmid:26227560
Dorvignit D et al. Antitumor and cytotoxic properties of a humanized antibody specific for the GM3(Neu5Gc) ganglioside. 2015 Immunobiology pmid:26224247
Rodriguez-Zhurbenko N et al. Anti-NeuGcGM3 reactivity: a possible role of natural antibodies and B-1 cells in tumor immunosurveillance. 2015 Ann. N. Y. Acad. Sci. pmid:26214505
Piperno GM et al. Recombinant AAV-mediated in vivo long-term expression and antitumour activity of an anti-ganglioside GM3(Neu5Gc) antibody. 2015 Gene Ther. pmid:26181624
Veillon L et al. Identification of Ganglioside GM3 Molecular Species in Human Serum Associated with Risk Factors of Metabolic Syndrome. 2015 PLoS ONE pmid:26102277
Kaneko T et al. Histochemical and immunoelectron microscopic analysis of ganglioside GM3 in human kidney. 2015 Clin. Exp. Nephrol. pmid:24985965
Huang Q et al. A new liquid chromatography/tandem mass spectrometry method for quantification of gangliosides in human plasma. 2014 Anal. Biochem. pmid:24680754