Disease MeSH term: Diabetes Mellitus, Experimental

Possible associated with:

Structure name description Reference count
Omega-muricholic acid Omega-muricholic acid is a lipid of Sterol Lipids (ST) class. 29
Alpha-muricholic acid Alpha-muricholic acid is a lipid of Sterol Lipids (ST) class. 29
Beta-muricholic acid 39
1-octadecanoyl-sn-glycero-3-phosphocholine 1-octadecanoyl-sn-glycero-3-phosphocholine is a lipid of Glycerophospholipids (GP) class. 1-octadecanoyl-sn-glycero-3-phosphocholine is associated with abnormalities such as Septicemia. The involved functions are known as Phosphorylation, MAP kinase activity, Phagocytosis, protein serine/threonine kinase activity and Uptake. The associated genes with 1-octadecanoyl-sn-glycero-3-phosphocholine are FPR1 gene and OLR1 gene. The related lipids are Lysophosphatidylcholines. 42
Hyocholic acid Hyocholic acid is a lipid of Sterol Lipids (ST) class. 48
1-hexacosanol 1-hexacosanol is a lipid of Fatty Acyls (FA) class. 94
Baohuoside 1 Baohuoside 1 is a lipid of Polyketides (PK) class. 130
11,12-epetre 136
11,12-epoxyeicosatrienoic acid 143
Scutellarein 7-glucuronide Scutellarein 7-glucuronide is a lipid of Polyketides (PK) class. 184
Calycosin Calycosin is a lipid of Polyketides (PK) class. Calycosin is associated with abnormalities such as Degenerative polyarthritis and Ischemia. The involved functions are known as Biosynthetic Pathways, Process, Anabolism, trans-cinnamate 4-hydroxylase activity and Transcription, Genetic. Calycosin often locates in viral nucleocapsid location, Mucous Membrane and Cell membrane. 195
LMPK12112009 LMPK12112009 is a lipid of Polyketides (PK) class. 216
3beta-sitosterol 234
cis-erucic acid Cis-erucic acid is a lipid of Fatty Acyls (FA) class. 251
O-propanoylcarnitine O-propanoylcarnitine is a lipid of Fatty Acyls (FA) class. 258
Glabridin Glabridin is a lipid of Polyketides (PK) class. Glabridin is associated with abnormalities such as Atherosclerosis, CNS disorder, Corn of toe, Fatty Liver and Obesity. The involved functions are known as Energy Absorption, Oxidation, Oxidants, Metabolic Process, Cellular and Drug Interactions. Glabridin often locates in Hepatic, membrane fraction, Microsomes, Microsomes, Liver and Extracellular. The associated genes with Glabridin are P4HTM gene, SPEN gene, SLC33A1 gene, ABCB1 gene and CD9 gene. The related lipids are Nonesterified Fatty Acids, Total cholesterol, Lipopolysaccharides, Hydroxycholesterols and 7-ketocholesterol. The related experimental models are Mouse Model. 263
NSC5548 NSC5548 is a lipid of Polyketides (PK) class. Nsc5548 is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Hyperglycemia, Coronary Arteriosclerosis, Liver diseases and Pulmonary Edema. The involved functions are known as Increased Sensitivy, Taste Perception, Cell Death, Phosphorylation and Signal Transduction. Nsc5548 often locates in Oral region, Cytoskeleton, Hepatic, Blood and Mouse Bone Marrow. The associated genes with NSC5548 are CA2 gene, P4HTM gene, FPGT gene, glycyl-L-phenylalanine and glycylphenylalanine. The related lipids are butyrate, Lipid Peroxides, blood lipid, Sterols and Total cholesterol. 283
Methyl vinyl ketone Methyl vinyl ketone is a lipid of Fatty Acyls (FA) class. 287
ERIODICTYOL Eriodictyol is a lipid of Polyketides (PK) class. Eriodictyol is associated with abnormalities such as Hyperostosis, Diffuse Idiopathic Skeletal, Macular degeneration, Consumption-archaic term for TB, Retinal Diseases and PARAGANGLIOMAS 4. The involved functions are known as glutathione biosynthetic process, Cytoprotection, Oxidants, protein expression and Cell Survival. Eriodictyol often locates in Cytoplasmic matrix, Protoplasm, Cytoplasmic, Cell Fraction and Back. The associated genes with Eriodictyol are NQO, HMOX1 gene, IMPACT gene, RPS6KA3 gene and GDNF gene. 311
Rumenic acid Rumenic acid is a lipid of Fatty Acyls (FA) class. Rumenic acid is associated with abnormalities such as Atherosclerosis, Vascular lesions, Hyperlipidemia and Consumption-archaic term for TB. The involved functions are known as Fatty streaks, Transcriptional Activation, Atherogenesis, cholesterol transport and ATP binding. Rumenic acid often locates in Blood and Body tissue. The associated genes with Rumenic acid are ABCA1 gene, apolipoprotein SAA, FATE1 gene and TFCP2 gene. The related lipids are 9,11-linoleic acid, (E,Z)-isomer, 9,11-linoleic acid, Fatty Acids, 11-octadecenoic acid and Total cholesterol. 324
L-norvaline L-norvaline is a lipid of Fatty Acyls (FA) class. L-norvaline is associated with abnormalities such as Celiac Disease, Exanthema, Atherosclerosis, Plasmodium falciparum infection and Parasitemia. The involved functions are known as Anabolism, Saturated, Stimulus, Physiologic Organization and arginase activity. L-norvaline often locates in Extracellular, Protoplasm, soluble, viral nucleocapsid location and Cell Wall. The associated genes with L-norvaline are norvaline, Amino Acids, Basic, ARG1 gene, Escherichia coli Proteins and Operon. The related lipids are Lipopolysaccharides. 328
11,12-eet 353
11s,12r-epetre 11s,12r-epetre is a lipid of Fatty Acyls (FA) class. 11s,12r-epetre is associated with abnormalities such as Hypertensive disease, Coronary Arteriosclerosis, Atherosclerosis, Ischemia and Vascular Diseases. The involved functions are known as inhibitors, Pathological Dilatation, Renal function, depolarization and Force. 11s,12r-epetre often locates in Body tissue, Epithelium, Cell membrane, apical membrane and Endothelium. The associated genes with 11s,12r-epetre are CYP2C18 gene, ADRBK1 gene, iberiotoxin and TNF gene. 353
11r,12s-epetre 11r,12s-epetre is a lipid of Fatty Acyls (FA) class. 11r,12s-epetre is associated with abnormalities such as Hypertensive disease, Coronary Arteriosclerosis, Atherosclerosis, Ischemia and Vascular Diseases. The involved functions are known as inhibitors, Pathological Dilatation, Renal function, depolarization and Force. 11r,12s-epetre often locates in Body tissue, Epithelium, Cell membrane, apical membrane and Endothelium. The associated genes with 11r,12s-epetre are CYP2C18 gene, ADRBK1 gene, iberiotoxin and TNF gene. 353
Beta-sitosterol Beta-sitosterol is a lipid of Sterol Lipids (ST) class. Beta-sitosterol is associated with abnormalities such as Obesity, Diabetes, Cholestasis, Systemic disease and Diabetes Mellitus. The involved functions are known as Increased Cholesterol Synthesis, Synthesis, cholesterol metabolism, GLUCOSE TOLERANCE and cholesterol absorption. Beta-sitosterol often locates in Blood, Back, Cell membrane, soluble fraction and Body tissue. The related lipids are Sterols, lathosterol, Total cholesterol, campesterol and Cholestanes. 380
beta-parinaric acid Beta-parinaric acid is a lipid of Fatty Acyls (FA) class. 416
PGF1alpha Pgf1alpha is a lipid of Fatty Acyls (FA) class. 418
Xanthohumol Xanthohumol is a lipid of Polyketides (PK) class. Xanthohumol is associated with abnormalities such as Endometriosis, site unspecified, Cyst, peritoneal lesion, Proliferative inflammation and furuncle. The involved functions are known as Cell Proliferation, Signal Transduction, Pathologic Neovascularization, Adverse effects and Proliferation (morphologic abnormality). Xanthohumol often locates in peritoneal, Mesentery, Membrane, Tissue specimen from uterus and Cell Nucleus. The associated genes with Xanthohumol are PI3 gene, KEAP1 gene, SLC33A1 gene, BCR-ABL Fusion Gene and BIRC5 gene. The related lipids are Fatty Acids and Palmitates. The related experimental models are Knock-out. 465
Clionasterol Clionasterol is a lipid of Sterol Lipids (ST) class. The involved functions are known as Intestinal Absorption. The related lipids are 22-hydroxycholesterol. 711
formononetin Formononetin is a lipid of Polyketides (PK) class. Formononetin is associated with abnormalities such as Infection, Dehydration, Mycoses, Consumption-archaic term for TB and Syndrome. The involved functions are known as Protein Overexpression, Methylation, Esthesia, Anabolism and enzyme activity. Formononetin often locates in soluble, Cytoplasmic matrix, Body tissue, Membrane and Tissue membrane. The associated genes with Formononetin are IMPACT gene, GLUCOSIDASE, Genes, Reporter, IGKV1-16 gene and GAL gene. The related experimental models are Knock-out. 790
hesperetin Hesperetin is a lipid of Polyketides (PK) class. Hesperetin is associated with abnormalities such as Corn of toe, Ischemia, Osteoporosis, Consumption-archaic term for TB and Wiskott-Aldrich Syndrome. The involved functions are known as conjugation, inhibitors, Process, mRNA Expression and Adjudication. Hesperetin often locates in Entire intestinal epithelium, Protoplasm, Membrane, Shoulder and Back. The associated genes with Hesperetin are ABCG2 gene, ABCC2 gene, FATE1 gene, ABCB1 gene and P-glycoprotein 2. 801
Fisetin Fisetin is a lipid of Polyketides (PK) class. Fisetin is associated with abnormalities such as Morphologically altered structure, PARKINSON DISEASE, LATE-ONSET, Tetanus, CNS disorder and Disintegration (morphologic abnormality). The involved functions are known as Autophagy, Apoptosis, Energy Metabolism, Acceleration and Anabolism. Fisetin often locates in Mitochondria, Cytoplasmic matrix, Extracellular, Cytoskeletal Filaments and Autophagic vacuole. The associated genes with Fisetin are SIRT1 gene, MAP1LC3A gene, TP53 gene, P4HTM gene and AURKB gene. The related lipids are Phosphatidylserines and Lipopolysaccharides. The related experimental models are Animal Cancer Model, Xenograft Model, Mouse Model, Cancer Model and Disease model. 832
n-heptanol N-heptanol is a lipid of Fatty Acyls (FA) class. N-heptanol is associated with abnormalities such as Corneal Neovascularization. N-heptanol often locates in Epithelium and Structure of corneal epithelium. The related lipids are Heptanol. 984
chrysin chrysin is a lipid of Polyketides (PK) class. Chrysin is associated with abnormalities such as Unconjugated hyperbilirubinemia, Metabolic Diseases, Hypogonadism, Renal tubular disorder and Colitis. The involved functions are known as Hypoxia, enzyme activity, Oxidation, inhibitors and Cell Survival. Chrysin often locates in Protoplasm, Plasma membrane, Back, Extracellular and Mitochondria. The associated genes with chrysin are CFB gene, P4HTM gene, UGT1A9 gene, CYP1A1 gene and UGT1A1 gene. The related lipids are Promega, estradiol-3-glucuronide, Steroids and Lipopolysaccharides. The related experimental models are Mouse Model. 1085
13,14-dihydro-15-keto-PGF2alpha 13,14-dihydro-15-keto-pgf2alpha is a lipid of Fatty Acyls (FA) class. 1147
rottlerin Rottlerin is a lipid of Polyketides (PK) class. Rottlerin is associated with abnormalities such as PARAGANGLIOMAS 2, Hyperostosis, Diffuse Idiopathic Skeletal, Virus Diseases, Perisylvian syndrome and Autoimmune disease (systemic) NOS. The involved functions are known as Apoptosis, Regulation, Signal Transduction, inhibitors and Proteasome Inhibitors [MoA]. Rottlerin often locates in Clone, Membrane, Body tissue, Plasma membrane and soluble. The associated genes with Rottlerin are XIAP gene, GAPDH gene, ICAM1 gene, P4HTM gene and TNFSF10 gene. The related lipids are Promega, Fatty Acids, Sphingolipids, Lipopolysaccharides and Saponin. The related experimental models are Mouse Model, Xenograft Model and Cancer Model. 1198
20-HETE 20-hete is a lipid of Fatty Acyls (FA) class. 20-hete is associated with abnormalities such as Cyst, Kidney Diseases, Kidney Failure, Chronic, Cystic Kidney Diseases and Simple renal cyst. The involved functions are known as Phosphorylation, inhibitors, Hypertrophy, Epithelial Cell Proliferation and Anabolism. 20-hete often locates in Mouse Kidney, Microsomes, Tissue membrane, Body tissue and Cytoplasmic matrix. The associated genes with 20-HETE are CYP4F3 gene, PKHD1 gene, Transgenes, P4HTM gene and CYP2E1 gene. The related lipids are Promega, enterodiol, Fatty Acids, hexanoic acid and U 73343. The related experimental models are Mouse Model, Knock-out, Streptozotocin Diabetes, Transgenic Model and Rodent Model. 1257
SCHEMBL105486 Kakonein is a lipid of Polyketides (PK) class. Kakonein is associated with abnormalities such as Fatty Liver, Chronic liver disease, Morphologically altered structure, Hypertensive disease and Cardiovascular Diseases. The involved functions are known as protein expression, Extravasation, Liver damage, mRNA Expression and cell activation. Kakonein often locates in Body tissue, Hepatic, Microvilli, Cytoplasm and Membrane. The associated genes with Kakonein are TJP1 gene, CD14 gene, iberiotoxin, AT-Rich Interactive Domain-Containing Protein 1A and NKS1 gene. The related lipids are dehydrosoyasaponin I and Steroids. The related experimental models are Knock-out. 1391
Carvacrol Carvacrol is a lipid of Prenol Lipids (PR) class. Carvacrol is associated with abnormalities such as Consumption-archaic term for TB, Disintegration (morphologic abnormality), Infection, Corn of toe and Candidiasis of vagina. The involved functions are known as Stereochemistry, Anabolism, Oxidation, Process and Binding (Molecular Function). Carvacrol often locates in Skin, Nerve Tissue, Membrane, Endothelium and Plasma membrane. The associated genes with Carvacrol are P4HTM gene, TRPV3 gene, TRPV1 gene, TRPV2 gene and TRPV4 gene. The related lipids are Fatty Acids, Lipopolysaccharides, Octanols, Micelles and butyrate. 1535
hypericin hypericin is a lipid of Polyketides (PK) class. Hypericin is associated with abnormalities such as Dermatitis, Phototoxic, Dehydration, Photosensitization, Morphologically altered structure and Myocardial Infarction. The involved functions are known as Cell Cycle Checkpoints, Apoptosis, Acetylation, Cell Survival and Caspase Activation. Hypericin often locates in insoluble fraction, Cytoplasmic matrix, Protoplasm, Tissue membrane and Cytoplasm. The associated genes with hypericin are CDC37 gene, HSPA8 gene, RAF1 gene, cyclin H and FK228. The related lipids are Phosphatidylserines. 1752
(-)-Limonene (-)-limonene is a lipid of Prenol Lipids (PR) class. (-)-limonene often locates in Kinetochores. 1786
myricetin myricetin is a lipid of Polyketides (PK) class. Myricetin is associated with abnormalities such as Diabetes, First myocardial infarction, Diabetes Mellitus, Non-Insulin-Dependent, Asthma and Cataract. The involved functions are known as Cell Survival, inhibitors, Process, Metabolic Inhibition and Oxidation. Myricetin often locates in Fibril - cell component, soluble, Body tissue, Back and Tissue membrane. The associated genes with myricetin are HPGDS gene, P4HTM gene, CFLAR gene, SLC2A2 gene and SLC2A1 gene. The related lipids are Promega, Sterols, dipalmitoylphosphatidylserine, 1,2-oleoylphosphatidylcholine and Membrane Lipids. 1801
2-arachidonoylglycerol 2-arachidonoylglycerol is a lipid of Glycerolipids (GL) class. 2-arachidonoylglycerol is associated with abnormalities such as Atherosclerosis, Heart Diseases, Inflammatory disorder, Colitis and Peripheral Neuropathy. The involved functions are known as Immunoreactivity, inhibitors, Stimulus, Esthesia and Signal Transduction. 2-arachidonoylglycerol often locates in Back, Presynaptic Terminals, Brain region, Blood and Body tissue. The associated genes with 2-arachidonoylglycerol are ADRBK1 gene, Homologous Gene, MGLL gene, PLA2G4A gene and peptide V. The related lipids are oleoylethanolamide, Lipopolysaccharides, Promega, stearic acid and 1-stearoyl-2-arachidonoylglycerol. The related experimental models are Knock-out. 1892
gamma-Linolenic acid Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system. 1919
baicalein baicalein is a lipid of Polyketides (PK) class. Baicalein is associated with abnormalities such as Neurodegenerative Disorders, Fibrillation, Hypertensive disease, Aortic coarctation and Coronary Occlusion. The involved functions are known as Anabolism, Polymerization, Process, inhibitors and Pathogenesis. Baicalein often locates in Membrane, Lipid Bilayers, soluble, Cell-Free System and Protoplasm. The associated genes with baicalein are P4HTM gene, BIRC5 gene, TSPO gene, SHOC2 gene and XIAP gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, iodoresiniferatoxin, Lipopolysaccharides and 17-octadecynoic acid. The related experimental models are Knock-out, Mouse Model and Parkinsonism, Experimental. 1997
Sphingosine 1-phosphate Sphingosine 1-phosphate is a lipid of Sphingolipids (SP) class. Sphingosine 1-phosphate is associated with abnormalities such as Infection, Painful Bladder Syndrome, Atherosclerosis, Hyperglycemia and Rheumatoid Arthritis. The involved functions are known as Phosphorylation, Regulation, enzyme activity, Energy Absorption and Vascular Permeability. Sphingosine 1-phosphate often locates in Endothelium, Tissue membrane, Vascular System, Protoplasm and Microfilaments. The associated genes with Sphingosine 1-phosphate are MBTPS1 gene, FBXL15 gene, TEK gene, NTRK1 gene and Gene Family. The related lipids are Promega, Lipopolysaccharides, lysophosphatidic acid, Lysophosphatidylcholines and Lysophospholipids. The related experimental models are Knock-out, Mouse Model, Transgenic Model, Disease model and Experimental Autoimmune Encephalomyelitis. 2005
FLAVONE FLAVONE is a lipid of Polyketides (PK) class. Flavone is associated with abnormalities such as Cardiovascular Diseases, Cerebrovascular accident, DERMATITIS HERPETIFORMIS, FAMILIAL, Hyperinsulinism and Inflammatory disorder. The involved functions are known as Oxidation-Reduction, Metabolic Inhibition, Inflammation, Phosphorylation and antioxidant activity. Flavone often locates in Endothelium, Hepatic, Protoplasm, Body tissue and Extracellular. The associated genes with FLAVONE are ICAM1 gene, BCL2L1 gene, MYC gene, TP53 gene and cytochrome c''. The related lipids are Promega, Steroids and Total cholesterol. The related experimental models are Knock-out, Disease model and Animal Disease Models. 2093
15-F2t-IsoP 15-f2t-isop is a lipid of Fatty Acyls (FA) class. 15-f2t-isop is associated with abnormalities such as Diabetes Mellitus, Acute coronary syndrome, Risk factor, cardiovascular, thrombocytosis and Chronic ischemic heart disease NOS. The involved functions are known as Anabolism, Inflammation, Lipid Peroxidation, Excretory function and Platelet Activation. The associated genes with 15-F2t-IsoP are PTGS2 gene. 2120
Dichloroacetic acid Dichloroacetic acid is a lipid of Fatty Acyls (FA) class. Dichloroacetic acid is associated with abnormalities such as Acidosis, Lactic, Metabolic Diseases, CLEFT LIP, CONGENITAL HEALED, Asthma and hyperthyroid. The involved functions are known as inhibitors, Chlorination, Metabolic Inhibition, Process and Sterility. Dichloroacetic acid often locates in Intestine - Large Intestine - Cecum (MMHCC), Mouse Liver, Back and Head. The associated genes with Dichloroacetic acid are GSTZ1 gene, PSMA5 gene and Maleylacetoacetate isomerase. The related lipids are Nonesterified Fatty Acids. 2361
bishomo-gamma-linolenic acid Bishomo-gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. Bishomo-gamma-linolenic acid is associated with abnormalities such as Diabetes, Obesity, Hypertensive disease, Cirrhosis and Hepatorenal Syndrome. The involved functions are known as Oxidation, Process, Metabolic Inhibition, epoxide hydrolase activity and Signal Transduction Pathways. Bishomo-gamma-linolenic acid often locates in Protoplasm, Cytoplasmic matrix, soluble, Membrane and Tissue membrane. The associated genes with bishomo-gamma-linolenic acid are P4HTM gene, IMPACT gene, arginine methyl ester, CYP gene and PTGS1 gene. The related lipids are Fatty Acids, 17-octadecynoic acid, Lipopolysaccharides, palmitoleic acid and nervonic acid. The related experimental models are Knock-out and Mouse Model. 2467
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