Disease MeSH term: Cardiomegaly

Possible associated with:

Structure name description Reference count
acetic acid acetic acid is a lipid of Fatty Acyls (FA) class. Acetic acid is associated with abnormalities such as Vitamin B 12 Deficiency. The involved functions are known as Excretory function. The related lipids are Propionate. 89633
propionic acid propionic acid is a lipid of Fatty Acyls (FA) class. Propionic acid is associated with abnormalities such as Epilepsy, Infection, Tuberculosis, Alkalosis and Ischemia. The involved functions are known as Uptake, Biosynthetic Pathways, Methylation, Protein Overexpression and Biochemical Pathway. Propionic acid often locates in Body tissue, Cytoplasmic matrix, Membrane, Protoplasm and Extracellular. The associated genes with propionic acid are TRIO gene, TRRAP gene, SLC5A8 gene, SLC33A1 gene and Homologous Gene. The related lipids are Fatty Acids, Propionate, butyrate, Valerates and mycocerosic acid. 7360
bishomo-gamma-linolenic acid Bishomo-gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. Bishomo-gamma-linolenic acid is associated with abnormalities such as Diabetes, Obesity, Hypertensive disease, Cirrhosis and Hepatorenal Syndrome. The involved functions are known as Oxidation, Process, Metabolic Inhibition, epoxide hydrolase activity and Signal Transduction Pathways. Bishomo-gamma-linolenic acid often locates in Protoplasm, Cytoplasmic matrix, soluble, Membrane and Tissue membrane. The associated genes with bishomo-gamma-linolenic acid are P4HTM gene, IMPACT gene, arginine methyl ester, CYP gene and PTGS1 gene. The related lipids are Fatty Acids, 17-octadecynoic acid, Lipopolysaccharides, palmitoleic acid and nervonic acid. The related experimental models are Knock-out and Mouse Model. 2467
DHA Dha is a lipid of Fatty Acyls (FA) class. Dha is associated with abnormalities such as Atherosclerosis, Consumption-archaic term for TB, Chronic disease, Cardiovascular Diseases and Diabetes Mellitus, Non-Insulin-Dependent. The involved functions are known as Inflammation, Oxidation, fatty acid oxidation, Fatty Acid Metabolism and Lipid Metabolism. Dha often locates in Hepatic, Protoplasm, Mucous Membrane, Epithelium and outer membrane. The associated genes with DHA are IMPACT gene, FATE1 gene, GAPDH gene, THOC4 gene and SLC33A1 gene. The related lipids are stearidonic acid, Fatty Acids, Total cholesterol, Lipopolysaccharides and Dietary Fatty Acid. The related experimental models are Mouse Model, Transgenic Model, Animal Disease Models and Arthritis, Experimental. 11054
EPA Epa is a lipid of Fatty Acyls (FA) class. 5952
Pyruvic acid Pyruvic acid is a lipid of Fatty Acyls (FA) class. 27047
2-bromohexadecanoic acid 2-bromohexadecanoic acid is a lipid of Fatty Acyls (FA) class. 2-bromohexadecanoic acid is associated with abnormalities such as Varicosity and Coronavirus Infections. The involved functions are known as Cell Proliferation, Apoptosis, Binding (Molecular Function), Regulation and Biochemical Pathway. 2-bromohexadecanoic acid often locates in Membrane, Cytoplasm, Mitochondria, Cell surface and Extracellular. The associated genes with 2-bromohexadecanoic acid are SLC33A1 gene, GRK6 gene, RBP1 gene, DST gene and FATE1 gene. The related lipids are Palmitates, Fatty Acids, Nonesterified Fatty Acids, Fatty Acids, Unsaturated and Oleates. 425
Dichloroacetic acid Dichloroacetic acid is a lipid of Fatty Acyls (FA) class. Dichloroacetic acid is associated with abnormalities such as Acidosis, Lactic, Metabolic Diseases, CLEFT LIP, CONGENITAL HEALED, Asthma and hyperthyroid. The involved functions are known as inhibitors, Chlorination, Metabolic Inhibition, Process and Sterility. Dichloroacetic acid often locates in Intestine - Large Intestine - Cecum (MMHCC), Mouse Liver, Back and Head. The associated genes with Dichloroacetic acid are GSTZ1 gene, PSMA5 gene and Maleylacetoacetate isomerase. The related lipids are Nonesterified Fatty Acids. 2361
2,5-diaminopentanoic acid 2,5-diaminopentanoic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Vasodilation, Intestinal Absorption and Pinocytosis. 2,5-diaminopentanoic acid often locates in Mitochondria, Microfilaments, NADH dehydrogenase complex and respiratory chain complex III location sensu Eukarya. The associated genes with 2,5-diaminopentanoic acid are GAPDH gene and iberiotoxin. 8868
11beta-PGF2 11beta-pgf2 is a lipid of Fatty Acyls (FA) class. 15009
n-heptanol N-heptanol is a lipid of Fatty Acyls (FA) class. N-heptanol is associated with abnormalities such as Corneal Neovascularization. N-heptanol often locates in Epithelium and Structure of corneal epithelium. The related lipids are Heptanol. 984
2,3-butanedione 2,3-butanedione is a lipid of Fatty Acyls (FA) class. The involved functions are known as Physiologic Organization, Biochemical Pathway, physiological aspects, establishment and maintenance of localization and Phosphorylation. 2,3-butanedione often locates in Membrane, Microfilaments, Microtubules, Cell body of neuron and filamentous actin location. The associated genes with 2,3-butanedione are SLC33A1 gene and WASF1 gene. 2715
Trilinolein Trilinolein is a lipid of Glycerolipids (GL) class. 120
Platelet activating factor Platelet activating factor is a lipid of Glycerophospholipids (GP) class. Platelet activating factor is associated with abnormalities such as Atherosclerosis, Acute cholecystitis without calculus, Cholecystitis, Colitis and Cholecystitis, Acute. The involved functions are known as Cell Survival, Metabolic Inhibition, lipid oxidation, Apoptosis and Oxidation. Platelet activating factor often locates in soluble, Cellular Membrane, Smooth muscle (tissue), Intima and Tissue specimen. The associated genes with Platelet activating factor are apolipoprotein A-I Milano, Homologous Gene, TSPO gene, HBEGF gene and SLC33A1 gene. The related lipids are Hydroxycholesterols, Liposomes, 25-hydroxycholesterol, Lysophosphatidylcholines and Lipopolysaccharides. The related experimental models are Knock-out, Mouse Model and Transgenic Model. 7383
1-Oleoyl Lysophosphatidic Acid 1-Oleoyl Lysophosphatidic Acid is a lipid of Glycerophospholipids (GP) class. 1-oleoyl lysophosphatidic acid is associated with abnormalities such as Myocardial Infarction, early pregnancy, Scleroderma, Blind Vision and Hyperlipidemia. The involved functions are known as Agent, Blood coagulation, Selection, Genetic, Analyte and Biological Processes. 1-oleoyl lysophosphatidic acid often locates in Tissue specimen, Body tissue, Blood, Membrane and Skin. The associated genes with 1-Oleoyl Lysophosphatidic Acid are Mucin-16, Peptides, SMAD4 gene, RND1 gene and Polypeptides. The related lipids are lysophosphatidic acid, A(2)C, Lysophospholipids, Fatty Acids and sphingosine 1-phosphate. The related experimental models are Mouse Model, Knock-out, Cancer Model, Xenograft Model and Arthritis, Adjuvant-Induced. 3463
trichostatin A Trichostatin is a lipid of Polyketides (PK) class. Trichostatin is associated with abnormalities such as Dentatorubral-Pallidoluysian Atrophy, PARAGANGLIOMAS 3, abnormal fragmented structure, Disintegration (morphologic abnormality) and Hyperostosis, Diffuse Idiopathic Skeletal. The involved functions are known as Acetylation, Cell Differentiation process, histone modification, Gene Silencing and Transcriptional Activation. Trichostatin often locates in CD41a, Hematopoietic System, Chromatin Structure, Blood and Endothelium. The associated genes with Trichostatin are SPI1 gene, CELL Gene, Chromatin, CXCR4 gene and DNMT1 gene. The related lipids are Butyrates, Promega, butyrate, Lipopolysaccharides and Steroids. The related experimental models are Knock-out, Mouse Model, Xenograft Model and Cancer Model. 5401
tacrolimus Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene. 12730
erythromycin erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out. 19871
(-)-Epigallocatechin gallate (-)-Epigallocatechin gallate is a lipid of Polyketides (PK) class. (-)-epigallocatechin gallate is associated with abnormalities such as IMMUNE SUPPRESSION, Infection, Nodule, Lymphopenia and Tumor Immunity. The involved functions are known as Apoptosis, Cellular Immune Response, Specific immune response, Signal and Infiltration. (-)-epigallocatechin gallate often locates in Immune system, Cytoplasmic Granules, Skin, Protoplasm and Body tissue. The associated genes with (-)-Epigallocatechin gallate are C8orf4 gene, Genes, vpr, MAPK8 gene, P4HTM gene and GAG Gene. The related lipids are Promega, Lipopolysaccharides, Palmitates, Fatty Acids and Sphingolipids. The related experimental models are Mouse Model, Xenograft Model, Transgenic Model, Experimental Autoimmune Encephalomyelitis and Arthritis, Collagen-Induced. 6551
Crotalarin Crotalarin is a lipid of Polyketides (PK) class. 2
quercetin quercetin is a lipid of Polyketides (PK) class. Quercetin is associated with abnormalities such as Coronary heart disease, Myocardial Infarction, Cirrhosis, Coronary Arteriosclerosis and Vascular ring. The involved functions are known as Vasodilation, physiological aspects, Fermentation, Process and Ingredient. Quercetin often locates in Arterial system, Endothelium, Skin, Endothelium, Vascular and Tissue specimen. The associated genes with quercetin are P4HTM gene, SULT gene, UGT1A1 gene, ARHGAP26 gene and PLXNB1 gene. The related lipids are blood lipid, Promega, Steroids, Phosphatidylserines and Fatty Acids. The related experimental models are Knock-out, Mouse Model, Xenograft Model, Tissue Model and Cancer Model. 5377
rottlerin Rottlerin is a lipid of Polyketides (PK) class. Rottlerin is associated with abnormalities such as PARAGANGLIOMAS 2, Hyperostosis, Diffuse Idiopathic Skeletal, Virus Diseases, Perisylvian syndrome and Autoimmune disease (systemic) NOS. The involved functions are known as Apoptosis, Regulation, Signal Transduction, inhibitors and Proteasome Inhibitors [MoA]. Rottlerin often locates in Clone, Membrane, Body tissue, Plasma membrane and soluble. The associated genes with Rottlerin are XIAP gene, GAPDH gene, ICAM1 gene, P4HTM gene and TNFSF10 gene. The related lipids are Promega, Fatty Acids, Sphingolipids, Lipopolysaccharides and Saponin. The related experimental models are Mouse Model, Xenograft Model and Cancer Model. 1198
doxorubicin Adriamycin is a lipid of Polyketides (PK) class. Adriamycin is associated with abnormalities such as Cardiomyopathies. The involved functions are known as Transcription, Genetic, Process, Drug effect disorder, Diastasis and Oxidation-Reduction. Adriamycin often locates in Muscle, Myocardium and Entire gastrointestinal tract. 54913
Parthenolide Parthenolide is a lipid of Prenol Lipids (PR) class. Parthenolide is associated with abnormalities such as Migraine Disorders, abnormal fragmented structure, Hyperostosis, Diffuse Idiopathic Skeletal, Consumption-archaic term for TB and Infection. The involved functions are known as Apoptosis, Cell Proliferation, Inflammation, pathologic cytolysis and Membrane Potentials. Parthenolide often locates in Mitochondria, Tissue membrane, Cytoplasmic matrix, Cytoplasm and Body tissue. The associated genes with Parthenolide are IGKJ1 gene, BCL2 gene, DDIT3 gene, Procaspase 7 and GAPDH gene. The related lipids are A(2)C. The related experimental models are Mouse Model, Xenograft Model, Breast Cancer Model and Cancer Model. 925
Artemisin Artemisin is a lipid of Prenol Lipids (PR) class. Artemisin is associated with abnormalities such as Malaria, Falciparum. The involved functions are known as Pressure- physical agent and secondary metabolic process. 4738
Thapsigargin Thapsigargin is a lipid of Prenol Lipids (PR) class. Thapsigargin is associated with abnormalities such as Impaired glucose tolerance, Obesity and Blood Pressure Disorders. The involved functions are known as Phosphorylation, establishment and maintenance of localization, Regulation, Metabolic Inhibition and Proteolysis. Thapsigargin often locates in Mouse Skin, Cytoplasm, Skin, Protoplasm and Mitochondria. The associated genes with Thapsigargin are ERBB4 gene, F11 gene, CA1 gene, TRNAP1 gene and HSPA5 gene. The related lipids are taurolithocholic acid 3-sulfate, Liposomes, Fatty Acids and stearylamine. The related experimental models are Mouse Model. 8868
Crocetin Crocetin is a lipid of Prenol Lipids (PR) class. Crocetin is associated with abnormalities such as abnormal fragmented structure, Gout, Infection and athymia. The involved functions are known as Cytokinesis, Anabolism, enzyme mechanism, Pathological accumulation of air in tissues and Hemorrhage. Crocetin often locates in Vacuole, Cytoplasmic matrix, Body tissue, Mitochondria and Blood. The associated genes with Crocetin are cytochrome c'', BCL2 gene and PCNA gene. The related lipids are mycorradicin. 350
forskolin Forskolin is a lipid of Prenol Lipids (PR) class. Forskolin is associated with abnormalities such as Cholestasis, Vocal cord dysfunction familial, Hypothyroidism, Renal tubular disorder and Disintegration (morphologic abnormality). The involved functions are known as Cell Proliferation, Anabolism, mRNA Expression, Agent and Signal. Forskolin often locates in Extracellular, Body tissue, Skin, Tissue membrane and Membrane. The associated genes with forskolin are P4HTM gene, SLC33A1 gene, NR1I2 gene, Genes, Reporter and CYP3A gene. The related lipids are Steroids, steroid sulfate, Fatty Acids, LYSO-PC and Lipopolysaccharides. 24755
Phorbol Phorbol is a lipid of Prenol Lipids (PR) class. Phorbol is associated with abnormalities such as furuncle, Infection, endothelial dysfunction, Morphologically altered structure and Acute erythroleukemia. The involved functions are known as Tyrosine Phosphorylation, Metabolic Inhibition, Transcription, Genetic, Protein Biosynthesis and Signal. Phorbol often locates in Tissue membrane, Membrane, Cell surface, soluble and Cytoplasmic Domain. The associated genes with Phorbol are STAT3 gene, JAK2 gene, JUN gene, PROC gene and MAPK8 gene. The related lipids are Lipopolysaccharides, Phosphatidylserines, Liposomes, Fatty Acids and Octanols. 2082
phorbol 13-acetate 12-myristate Phorbol 13-acetate 12-myristate is a lipid of Prenol Lipids (PR) class. The involved functions are known as DNA Fragmentation, Phosphorylation and Irritation. Phorbol 13-acetate 12-myristate often locates in low-density lipoprotein particle. The associated genes with phorbol 13-acetate 12-myristate are FPR1 gene and ABCB1 gene. 40921
cholesterol cholesterol is a lipid of Sterol Lipids (ST) class. Cholesterol is associated with abnormalities such as Trypanosomiasis, Chagas Disease, Cleft Palate, Chondrodysplasia punctata 2, X-linked dominant and Child syndrome. The involved functions are known as Blood Circulation, Sterol Biosynthesis Pathway, Receptor Mediated Endocytosis, Methylation and Signal. Cholesterol often locates in Animal tissue, Blood, Membrane, Plasma membrane and peroxisome. The associated genes with cholesterol are MBD2 gene, SIM, SLC33A1 gene, Genome and NSDHL gene. The related lipids are Sterols, zymosterol, fecosterol, Total cholesterol and 7-dehydrocholesterol. The related experimental models are Mouse Model, Knock-out, Genetically Engineered Mouse and Disease model. 98461
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