|
butein |
Butein is a lipid of Polyketides (PK) class. Butein is associated with abnormalities such as Glomerulonephritis, Fibrosis, Liver, Kidney Failure, Acute, Mastocytosis and Chimera disorder. The involved functions are known as Phosphorylation, Transcription, Genetic, IkappaB kinase activity, Gene Expression and Signal Transduction. Butein often locates in Membrane, Cytoplasmic, IkappaB kinase complex, Protoplasm and Plasma membrane. The associated genes with Butein are ICAM1 gene, MAPK8 gene, MYC gene, BCL2 gene and BCL2L1 gene. The related lipids are Promega. The related experimental models are Xenograft Model, Knock-out and Mouse Model. |
190 |
|
licochalcone a |
licochalcone a is a lipid of Polyketides (PK) class. Licochalcone a is associated with abnormalities such as CLEFT LIP, CONGENITAL HEALED, Gastric ulcer, Keratoconjunctivitis Sicca, Inflammatory disorder and Leishmaniasis. The involved functions are known as 5-(carboxyamino)imidazole ribonucleotide mutase activity, Germination, Cell Growth, Metabolic Inhibition and Respiratory Chain. Licochalcone a often locates in Cell surface, Plasma membrane, IkappaB kinase complex, Mitochondria and Membrane. The associated genes with licochalcone a are HM13 gene, Salmine, cytochrome c'', TNFRSF1A gene and RIPK1 gene. The related lipids are Promega. |
220 |
|
phloretin |
phloretin is a lipid of Polyketides (PK) class. Phloretin is associated with abnormalities such as Atherosclerosis, Diabetes Mellitus, Non-Insulin-Dependent, Alkalemia, Renal tubular disorder and pathologic fistula. The involved functions are known as Anabolism, glycosyltransferase activity, Biosynthetic Pathways, Localized desquamation and Biological Processes. Phloretin often locates in soluble, BL21, Cytoplasmic, Extracellular and Cytoplasm. The associated genes with phloretin are Homologous Gene, CD36 gene, Candidate Disease Gene, SLC33A1 gene and PAK1IP1 gene. The related lipids are Liposomes, Palmitates, Fatty Acids, Sterols and 6-ketocholestanol. The related experimental models are Knock-out. |
2367 |
|
Prostaglandin e1 |
Prostaglandin e1 is a lipid of Fatty Acyls (FA) class. The involved functions are known as Protein Expression and Down-Regulation. |
5126 |
|
Liquiritigenin |
Liquiritigenin is a lipid of Polyketides (PK) class. Liquiritigenin is associated with abnormalities such as POSTMENOPAUSAL SYNDROME, Hyperostosis, Diffuse Idiopathic Skeletal, PARAGANGLIOMAS 2, Wiskott-Aldrich Syndrome and Alzheimer's Disease. The involved functions are known as Heterodimerization, Transcription, Genetic, Ligand Binding, Transcriptional Activation and Anabolism. Liquiritigenin often locates in Membrane, Blood, Microsomes, Liver, Microsomes and Body tissue. The associated genes with Liquiritigenin are Candidate Disease Gene, IMPACT gene, TNFSF10 gene, SLC33A1 gene and P4HTM gene. The related lipids are Lipopolysaccharides, pregnenolone sulfate and FuGene. The related experimental models are Xenograft Model. |
313 |
|
Pinocembrin |
Pinocembrin is a lipid of Polyketides (PK) class. Pinocembrin is associated with abnormalities such as Exanthema. The involved functions are known as Anabolism, Sulfation, Vmax, flavonoid biosynthetic process and Cell Death. The associated genes with Pinocembrin are SULT1A1 gene and NKS1 gene. |
172 |
|
Farrerol |
Farrerol is a lipid of Polyketides (PK) class. The involved functions are known as Transcription, Genetic, antioxidant activity, Metabolic Inhibition, Gene Expression and Hemolysis (biological funtion). The associated genes with Farrerol are SLC33A1 gene and Locus. |
49 |
|
hypericin |
hypericin is a lipid of Polyketides (PK) class. Hypericin is associated with abnormalities such as Dermatitis, Phototoxic, Dehydration, Photosensitization, Morphologically altered structure and Myocardial Infarction. The involved functions are known as Cell Cycle Checkpoints, Apoptosis, Acetylation, Cell Survival and Caspase Activation. Hypericin often locates in insoluble fraction, Cytoplasmic matrix, Protoplasm, Tissue membrane and Cytoplasm. The associated genes with hypericin are CDC37 gene, HSPA8 gene, RAF1 gene, cyclin H and FK228. The related lipids are Phosphatidylserines. |
1752 |
|
emodin |
emodin is a lipid of Polyketides (PK) class. Emodin is associated with abnormalities such as Infection, Conjunctivitis, Vernal, Stevens-Johnson Syndrome, Conjunctival scar and Allergic Conjunctivitis. The involved functions are known as signaling cascade, Metabolic Inhibition, Cell Death, Phosphorylation and JNK Pathway. Emodin often locates in Membrane, Protoplasm, Mitochondria, Cytoplasmic matrix and soluble. The associated genes with emodin are cytochrome c'', UTS2 gene, TK Gene, Gene Clusters and CFC1 gene. The related lipids are Phosphatidylserines, Promega, Sphingolipids, Membrane Lipids and Palmitates. The related experimental models are Mouse Model and Transgenic Model. |
1742 |
|
doxorubicin |
Adriamycin is a lipid of Polyketides (PK) class. Adriamycin is associated with abnormalities such as Cardiomyopathies. The involved functions are known as Transcription, Genetic, Process, Drug effect disorder, Diastasis and Oxidation-Reduction. Adriamycin often locates in Muscle, Myocardium and Entire gastrointestinal tract. |
54913 |
|
Alpha-terpinene |
Alpha-terpinene is a lipid of Prenol Lipids (PR) class. |
258 |
|
(+)-Camphor |
(+)-camphor is a lipid of Prenol Lipids (PR) class. (+)-camphor is associated with abnormalities such as Athetoid cerebral palsy. The involved functions are known as inhibitors, Synthesis, Feedback and Competitive inhibition. The associated genes with (+)-Camphor are 4S-limonene synthase. The related lipids are palmitoleic acid, pentadecanoic acid, stearic acid and erucic acid. |
3660 |
|
Camphorquinone |
Camphorquinone is a lipid of Prenol Lipids (PR) class. The involved functions are known as Polymerization. The related lipids are camphoroquinone. |
385 |
|
fumagillin |
Fumagillin is a lipid of Prenol Lipids (PR) class. Fumagillin is associated with abnormalities such as Atherosclerosis, Dentatorubral-Pallidoluysian Atrophy, Severe Combined Immunodeficiency, Immunologic Deficiency Syndromes and Arthritis. The involved functions are known as Gene Expression, Apoptosis, Angiogenic Process, Infiltration and Adverse effects. Fumagillin often locates in Endothelium, Body tissue, Blood, soluble and Protoplasm. The associated genes with fumagillin are HIST1H1C gene, RAC1 gene, c-myb Genes, METAP2 gene and NCKIPSD gene. The related lipids are helvolic acid, Butyrates and Butanols. The related experimental models are Mouse Model, Xenograft Model and Cancer Model. |
500 |
|
Parthenolide |
Parthenolide is a lipid of Prenol Lipids (PR) class. Parthenolide is associated with abnormalities such as Migraine Disorders, abnormal fragmented structure, Hyperostosis, Diffuse Idiopathic Skeletal, Consumption-archaic term for TB and Infection. The involved functions are known as Apoptosis, Cell Proliferation, Inflammation, pathologic cytolysis and Membrane Potentials. Parthenolide often locates in Mitochondria, Tissue membrane, Cytoplasmic matrix, Cytoplasm and Body tissue. The associated genes with Parthenolide are IGKJ1 gene, BCL2 gene, DDIT3 gene, Procaspase 7 and GAPDH gene. The related lipids are A(2)C. The related experimental models are Mouse Model, Xenograft Model, Breast Cancer Model and Cancer Model. |
925 |
|
Vomitoxin |
Vomitoxin is a lipid of Prenol Lipids (PR) class. Vomitoxin is associated with abnormalities such as Infection and Gastroenteritis. The involved functions are known as mRNA Expression, Inflammation, Transcription, Genetic, Protein Biosynthesis and Adverse effects. Vomitoxin often locates in Lymphoid Tissue, Immune system, Bone Marrow and Plasma membrane. The associated genes with Vomitoxin are IMPACT gene, HIST1H1C gene and RBM39 gene. The related experimental models are Mouse Model. |
2643 |
|
Artemisin |
Artemisin is a lipid of Prenol Lipids (PR) class. Artemisin is associated with abnormalities such as Malaria, Falciparum. The involved functions are known as Pressure- physical agent and secondary metabolic process. |
4738 |
|
Gossypol |
Gossypol is a lipid of Prenol Lipids (PR) class. Gossypol is associated with abnormalities such as Paralytic Ileus, PARKINSON DISEASE, LATE-ONSET, Fibrillation, Hepatic necrosis and Lymphopenia. The involved functions are known as Atrophic, Ulcer, Necrosis, Apoptosis and antagonists. Gossypol often locates in Mucous Membrane, Epithelium, Blood, Microsomes, Liver and Autophagic vacuole. The associated genes with Gossypol are BCL2A1 gene, BCL2 gene, Transgenes, IGH@ gene cluster and Bax protein (53-86). The related lipids are Promega, proteoliposomes, Phosphatidylserines and Liposomes. The related experimental models are Transgenic Model and Xenograft Model. |
2557 |
|
Crocetin |
Crocetin is a lipid of Prenol Lipids (PR) class. Crocetin is associated with abnormalities such as abnormal fragmented structure, Gout, Infection and athymia. The involved functions are known as Cytokinesis, Anabolism, enzyme mechanism, Pathological accumulation of air in tissues and Hemorrhage. Crocetin often locates in Vacuole, Cytoplasmic matrix, Body tissue, Mitochondria and Blood. The associated genes with Crocetin are cytochrome c'', BCL2 gene and PCNA gene. The related lipids are mycorradicin. |
350 |
|
forskolin |
Forskolin is a lipid of Prenol Lipids (PR) class. Forskolin is associated with abnormalities such as Cholestasis, Vocal cord dysfunction familial, Hypothyroidism, Renal tubular disorder and Disintegration (morphologic abnormality). The involved functions are known as Cell Proliferation, Anabolism, mRNA Expression, Agent and Signal. Forskolin often locates in Extracellular, Body tissue, Skin, Tissue membrane and Membrane. The associated genes with forskolin are P4HTM gene, SLC33A1 gene, NR1I2 gene, Genes, Reporter and CYP3A gene. The related lipids are Steroids, steroid sulfate, Fatty Acids, LYSO-PC and Lipopolysaccharides. |
24755 |
|
Dehydroabietic acid |
Dehydroabietic acid is a lipid of Prenol Lipids (PR) class. Dehydroabietic acid is associated with abnormalities such as Plague. The involved functions are known as RNA Interference and enzyme activity. Dehydroabietic acid often locates in Clone, Entire nervous system, Membrane and Cellular Membrane. |
311 |
|
isopimaric acid |
Isopimaric acid is a lipid of Prenol Lipids (PR) class. Isopimaric acid is associated with abnormalities such as Dehydration. The involved functions are known as Noise, Increased Sensitivy, nuclear mRNA cis splicing, via spliceosome, Diastasis and spore germination. Isopimaric acid often locates in Protoplasm, Body tissue, Muscle and Microsomes. The associated genes with isopimaric acid are KCNMA1 gene and iberiotoxin. |
55 |
|
Phorbol |
Phorbol is a lipid of Prenol Lipids (PR) class. Phorbol is associated with abnormalities such as furuncle, Infection, endothelial dysfunction, Morphologically altered structure and Acute erythroleukemia. The involved functions are known as Tyrosine Phosphorylation, Metabolic Inhibition, Transcription, Genetic, Protein Biosynthesis and Signal. Phorbol often locates in Tissue membrane, Membrane, Cell surface, soluble and Cytoplasmic Domain. The associated genes with Phorbol are STAT3 gene, JAK2 gene, JUN gene, PROC gene and MAPK8 gene. The related lipids are Lipopolysaccharides, Phosphatidylserines, Liposomes, Fatty Acids and Octanols. |
2082 |
|
phorbol 13-acetate 12-myristate |
Phorbol 13-acetate 12-myristate is a lipid of Prenol Lipids (PR) class. The involved functions are known as DNA Fragmentation, Phosphorylation and Irritation. Phorbol 13-acetate 12-myristate often locates in low-density lipoprotein particle. The associated genes with phorbol 13-acetate 12-myristate are FPR1 gene and ABCB1 gene. |
40921 |
|
Sphingosine 1-phosphate |
Sphingosine 1-phosphate is a lipid of Sphingolipids (SP) class. Sphingosine 1-phosphate is associated with abnormalities such as Infection, Painful Bladder Syndrome, Atherosclerosis, Hyperglycemia and Rheumatoid Arthritis. The involved functions are known as Phosphorylation, Regulation, enzyme activity, Energy Absorption and Vascular Permeability. Sphingosine 1-phosphate often locates in Endothelium, Tissue membrane, Vascular System, Protoplasm and Microfilaments. The associated genes with Sphingosine 1-phosphate are MBTPS1 gene, FBXL15 gene, TEK gene, NTRK1 gene and Gene Family. The related lipids are Promega, Lipopolysaccharides, lysophosphatidic acid, Lysophosphatidylcholines and Lysophospholipids. The related experimental models are Knock-out, Mouse Model, Transgenic Model, Disease model and Experimental Autoimmune Encephalomyelitis. |
2005 |
|
Glucosyl sphingosine |
Glucosyl sphingosine is a lipid of Sphingolipids (SP) class. Glucosyl sphingosine is associated with abnormalities such as Sphingolipidoses, Globoid cell leukodystrophy, Sandhoff Disease, Tay-Sachs Disease and Fabry Disease. The involved functions are known as Apoptosis, Acetylation, Infiltration, kinase activity and energy pathways. Glucosyl sphingosine often locates in Lysosomal and Protoplasm. The associated genes with Glucosyl sphingosine are MAPT gene, GALC gene, HEXA gene, PICK1 gene and ELF3 gene. The related lipids are lysoganglioside G(M2), Ganglioside GA2, Lysophosphatidylcholines and globotriaosyl lysosphingolipid. |
74 |
|
PSYCHOSINE |
PSYCHOSINE is a lipid of Sphingolipids (SP) class. Psychosine is associated with abnormalities such as Globoid cell leukodystrophy, Demyelinating Diseases, Multiple Sclerosis, nervous system disorder and Lysosomal Storage Diseases. The involved functions are known as Ionization, Pathogenesis, Demyelination, 5-(carboxyamino)imidazole ribonucleotide mutase activity and Increased Sensitivy. Psychosine often locates in Body tissue, CNS - Brain (MMHCC), Autosome, Peripheral Nervous System and Nerve Tissue. The associated genes with PSYCHOSINE are GALC gene, NTRK1 gene, JUN gene, ALPP gene and Polylysine. The related lipids are Fatty Acids, fatty aldehyde, lysophosphatidic acid, Stearic acid and stearoyl chloride. The related experimental models are Mouse Model and Streptozotocin Diabetes. |
281 |
|
cholesterol |
cholesterol is a lipid of Sterol Lipids (ST) class. Cholesterol is associated with abnormalities such as Trypanosomiasis, Chagas Disease, Cleft Palate, Chondrodysplasia punctata 2, X-linked dominant and Child syndrome. The involved functions are known as Blood Circulation, Sterol Biosynthesis Pathway, Receptor Mediated Endocytosis, Methylation and Signal. Cholesterol often locates in Animal tissue, Blood, Membrane, Plasma membrane and peroxisome. The associated genes with cholesterol are MBD2 gene, SIM, SLC33A1 gene, Genome and NSDHL gene. The related lipids are Sterols, zymosterol, fecosterol, Total cholesterol and 7-dehydrocholesterol. The related experimental models are Mouse Model, Knock-out, Genetically Engineered Mouse and Disease model. |
98461 |
|
DESMOSTEROL |
DESMOSTEROL is a lipid of Sterol Lipids (ST) class. Desmosterol is associated with abnormalities such as Cataract, Congenital Abnormality, Liver diseases, Erectile dysfunction and Multiple congenital anomalies. The involved functions are known as Bulla, Methylation, cholesterol biosynthetic process, Process and cholesterol efflux. Desmosterol often locates in Body tissue, Tissue membrane, Plasma membrane, Pore and Endoplasmic Reticulum. The associated genes with DESMOSTEROL are P4HTM gene, SHH gene, WDR48 gene, CFLAR gene and SLC33A1 gene. The related lipids are Sterols, androstanol, Steroids, Unilamellar Vesicles and 7-dehydrocholesterol. The related experimental models are Transgenic Model and Rodent Model. |
251 |
|
Digitonin |
Digitonin is a lipid of Sterol Lipids (ST) class. Digitonin is associated with abnormalities such as SCHOPF-SCHULZ-PASSARGE SYNDROME (disorder), Infection, BOSLEY-SALIH-ALORAINY SYNDROME, Hyperostosis, Diffuse Idiopathic Skeletal and FRONTOTEMPORAL DEMENTIA, CHROMOSOME 3-LINKED. The involved functions are known as Coprecipitation, establishment and maintenance of localization, Mutation, protein thiol-disulfide exchange and Receptor Binding. Digitonin often locates in Protoplasm, Cytoplasm, Membrane, Cytoplasmic matrix and Cytoplasmic Domain. The associated genes with Digitonin are Integral Membrane Proteins, Polypeptides, GOLPH3 gene, GAS1 gene and TRAF3IP2 gene. The related lipids are Promega, Sterols, 1,2-dihexadecyl-sn-glycero-3-phosphocholine, proteoliposomes and Lysophosphatidylcholines. |
2282 |
|
7-Dehydrocholesterol |
7-Dehydrocholesterol is a lipid of Sterol Lipids (ST) class. 7-dehydrocholesterol is associated with abnormalities such as Dehydration, Exanthema, RETINITIS PIGMENTOSA 49, Congenital Abnormality and Failure to Thrive. The involved functions are known as 5-(carboxyamino)imidazole ribonucleotide mutase activity, Mutation, Lysis, Anabolism and Biosynthetic Pathways. 7-dehydrocholesterol often locates in Plasma membrane, Body tissue, Tissue membrane, Membrane and outer membrane. The associated genes with 7-Dehydrocholesterol are mutant gene, THEMIS gene, IGKV1D-37 gene, LGALS4 gene and Orthologous Gene. The related lipids are Membrane Lipids, Steroids, Sterols, campesterol and 7-dehydrocholesterol. The related experimental models are Mouse Model, Knock-out and Rodent Model. |
545 |