Disease MeSH term: Adenocarcinoma

Possible associated with:

Structure name description Reference count
CYTOCHALASIN B CYTOCHALASIN B is a lipid of Polyketides (PK) class. Cytochalasin b is associated with abnormalities such as Renal tubular disorder and Chagas Disease. The involved functions are known as Membrane Protein Traffic, inhibitors, Metabolic Inhibition, Biochemical Pathway and Increased Sensitivy. Cytochalasin b often locates in Cytoplasmic matrix, Plasma membrane, Microtubules, Extracellular and Protoplasm. The associated genes with CYTOCHALASIN B are SLC2A2 gene, PFDN5 gene, SLC2A1 gene, OMG gene and SPEN gene. The related lipids are Steroids, Lipopolysaccharides and Liposomes. The related experimental models are Xenograft Model. 9648
Malvidin Malvidin is a lipid of Polyketides (PK) class. The involved functions are known as conjugation. 363
Gallocatechin (+)-gallocatechin is a lipid of Polyketides (PK) class. The involved functions are known as inhibitors and Cell Survival. The associated genes with (+)-Gallocatechin are TERT gene. 778
(-)-Epicatechin gallate (-)-Epicatechin gallate is a lipid of Polyketides (PK) class. (-)-epicatechin gallate is associated with abnormalities such as Infection, trachomatis, Heart Diseases, Influenza and Hypoglycemia. The involved functions are known as Cell Proliferation, Metabolic Inhibition, Anabolism, protein expression and Apoptosis. (-)-epicatechin gallate often locates in Tissue membrane, Membrane, soluble, Plasma membrane and Protoplasm. The associated genes with (-)-Epicatechin gallate are GDF15 gene, ATF3 gene, CRISP2 gene, Homologous Gene and activating transcription factor 3. The related lipids are Lipopolysaccharides. The related experimental models are Cancer Model and Mouse Model. 645
(-)-Epigallocatechin gallate (-)-Epigallocatechin gallate is a lipid of Polyketides (PK) class. (-)-epigallocatechin gallate is associated with abnormalities such as IMMUNE SUPPRESSION, Infection, Nodule, Lymphopenia and Tumor Immunity. The involved functions are known as Apoptosis, Cellular Immune Response, Specific immune response, Signal and Infiltration. (-)-epigallocatechin gallate often locates in Immune system, Cytoplasmic Granules, Skin, Protoplasm and Body tissue. The associated genes with (-)-Epigallocatechin gallate are C8orf4 gene, Genes, vpr, MAPK8 gene, P4HTM gene and GAG Gene. The related lipids are Promega, Lipopolysaccharides, Palmitates, Fatty Acids and Sphingolipids. The related experimental models are Mouse Model, Xenograft Model, Transgenic Model, Experimental Autoimmune Encephalomyelitis and Arthritis, Collagen-Induced. 6551
(-)-Epigallocatechin (-)-Epigallocatechin is a lipid of Polyketides (PK) class. The involved functions are known as Protective Agents, inhibitors, Process, Drug Kinetics and Fermentation. (-)-epigallocatechin often locates in Hepatic, Blood, Membrane, Back and apical membrane. The associated genes with (-)-Epigallocatechin are ADRBK1 gene and FASTK Gene. The related lipids are 1,2-dilinolenoyl-3-(4-aminobutyryl)propane-1,2,3-triol. The related experimental models are Rodent Model and Transgenic Model. 1282
Quercetin 3-beta-D-glucoside Quercetin 3-alloside is a lipid of Polyketides (PK) class. Quercetin 3-alloside is associated with abnormalities such as Vitelliform dystrophy. The involved functions are known as sugar binding and Docking. 319
Quercetin 3-beta-D-glucoside Quercetin 3-alloside is a lipid of Polyketides (PK) class. Quercetin 3-alloside is associated with abnormalities such as Vitelliform dystrophy. The involved functions are known as sugar binding and Docking. 319
Fisetin Fisetin is a lipid of Polyketides (PK) class. Fisetin is associated with abnormalities such as Morphologically altered structure, PARKINSON DISEASE, LATE-ONSET, Tetanus, CNS disorder and Disintegration (morphologic abnormality). The involved functions are known as Autophagy, Apoptosis, Energy Metabolism, Acceleration and Anabolism. Fisetin often locates in Mitochondria, Cytoplasmic matrix, Extracellular, Cytoskeletal Filaments and Autophagic vacuole. The associated genes with Fisetin are SIRT1 gene, MAP1LC3A gene, TP53 gene, P4HTM gene and AURKB gene. The related lipids are Phosphatidylserines and Lipopolysaccharides. The related experimental models are Animal Cancer Model, Xenograft Model, Mouse Model, Cancer Model and Disease model. 832
Lupeol Lupeol is a lipid of Prenol Lipids (PR) class. Lupeol is associated with abnormalities such as Morphologically altered structure, Infection, protrusion, Consumption-archaic term for TB and PARAGANGLIOMAS 2. The involved functions are known as Transcriptional Activation, Agent, Tumorigenicity, Signal and inhibitors. Lupeol often locates in Body tissue, Membrane, Cytoplasmic, Stress Fibers and Filopodia. The associated genes with Lupeol are Candidate Disease Gene, SPEN gene, AR gene, SGK1 gene and TIPARP gene. The related lipids are Sterols, Micelles, campesterol, amyrin and campestanol. The related experimental models are Mouse Model and Xenograft Model. 844
Lycopene Lycopene is a lipid of Prenol Lipids (PR) class. Lycopene is associated with abnormalities such as Consumption-archaic term for TB, Chronic disease, Dehydration, furuncle and Cardiovascular Diseases. The involved functions are known as Cell Differentiation process, Signal Transduction, Biochemical Pathway, Mutation and IGF-1 Signaling Pathway. Lycopene often locates in Body tissue, Hepatic, Blood, Adipose tissue and Structure of parenchyma of lung. The associated genes with Lycopene are EPB41L2 gene, VEGFB gene, P4HTM gene, FATE1 gene and SLC33A1 gene. The related lipids are Micelles, Liposomes, Total cholesterol, Steroids and apo-10'-lycopenoic acid. The related experimental models are Mouse Model, Knock-out, Cancer Model, Transgenic Model and Xenograft Model. 3986
Ginkgetin Ginkgetin is a lipid of Polyketides (PK) class. 71
SCHEMBL105486 Kakonein is a lipid of Polyketides (PK) class. Kakonein is associated with abnormalities such as Fatty Liver, Chronic liver disease, Morphologically altered structure, Hypertensive disease and Cardiovascular Diseases. The involved functions are known as protein expression, Extravasation, Liver damage, mRNA Expression and cell activation. Kakonein often locates in Body tissue, Hepatic, Microvilli, Cytoplasm and Membrane. The associated genes with Kakonein are TJP1 gene, CD14 gene, iberiotoxin, AT-Rich Interactive Domain-Containing Protein 1A and NKS1 gene. The related lipids are dehydrosoyasaponin I and Steroids. The related experimental models are Knock-out. 1391
daidzein daidzein is a lipid of Polyketides (PK) class. Daidzein is associated with abnormalities such as Cardiovascular Diseases, Osteoporosis, Heart Diseases, Thyroid Diseases and Exanthema. The involved functions are known as Cell Growth, Disease Progression, metaplastic cell transformation, Cell Cycle and M Phase Cell Cycle Arrest. Daidzein often locates in Urothelium, Mucous Membrane, Chromosomes, Epithelium and Ribosomes. The associated genes with daidzein are Tumor Suppressor Genes, Genome, TIRAP gene, TICAM2 gene and Candidate Disease Gene. The related lipids are Promega, Steroids, Saponins, enterodiol and linoleates. The related experimental models are Xenograft Model, Knock-out, Mouse Model, Breast Cancer Model and Arthritis, Experimental. 4463
genistein 7-O-glucoside genistein 7-O-glucoside is a lipid of Polyketides (PK) class. Genistein 7-o-glucoside is associated with abnormalities such as athymia, Heart Diseases, Thyroid Diseases, Plague and Brucella infections. The involved functions are known as Cell Proliferation, Binding (Molecular Function), Ingestion, topoisomerase activity and kinase activity. Genistein 7-o-glucoside often locates in Membrane, Gastrointestinal tract structure, Oral region, Body tissue and Blood. The associated genes with genistein 7-O-glucoside are GLUCOSIDASE, PPP1R1A gene, Homologous Gene, Genome and FUSE gene. The related lipids are Sterols, 1,2-oleoylphosphatidylcholine, Membrane Lipids and DOPE. 264
rotenone rotenone is a lipid of Polyketides (PK) class. Rotenone is associated with abnormalities such as Parkinson Disease, MYOPATHY, DISTAL, WITH ANTERIOR TIBIAL ONSET, Neurodegenerative Disorders, Septicemia and Respiratory Failure. The involved functions are known as Phosphorylation, Process, Cell Death, proteasome activity and Apoptosis. Rotenone often locates in Protoplasm, Presynaptic Terminals, Neurites, NADH dehydrogenase complex and Mitochondria. The associated genes with rotenone are DNAJB9 gene, EIF2S3 gene, Candidate Disease Gene, G-substrate and ERN1 gene. The related lipids are Lipopolysaccharides, Membrane Lipids, Phosphatidylserines, Fatty Acids and Cardiolipins. The related experimental models are Knock-out, Mouse Model, Disease model and Rodent Model. 7079
Glabridin Glabridin is a lipid of Polyketides (PK) class. Glabridin is associated with abnormalities such as Atherosclerosis, CNS disorder, Corn of toe, Fatty Liver and Obesity. The involved functions are known as Energy Absorption, Oxidation, Oxidants, Metabolic Process, Cellular and Drug Interactions. Glabridin often locates in Hepatic, membrane fraction, Microsomes, Microsomes, Liver and Extracellular. The associated genes with Glabridin are P4HTM gene, SPEN gene, SLC33A1 gene, ABCB1 gene and CD9 gene. The related lipids are Nonesterified Fatty Acids, Total cholesterol, Lipopolysaccharides, Hydroxycholesterols and 7-ketocholesterol. The related experimental models are Mouse Model. 263
HEMATOXYLIN HEMATOXYLIN is a lipid of Polyketides (PK) class. Hematoxylin is associated with abnormalities such as Eosinophilia, Duodenal Adenoma, Senile Plaques, Morphologically altered structure and Cervical abscess. The involved functions are known as Uptake, Apoptosis, Amplification, Necrosis and Karyopyknosis. Hematoxylin often locates in Body tissue, Extracellular, Compact bone, Skin and Basement membrane. The associated genes with HEMATOXYLIN are GAPDH gene, Genome, Elastin, MERTK wt Allele and P4HTM gene. 6127
myricetin myricetin is a lipid of Polyketides (PK) class. Myricetin is associated with abnormalities such as Diabetes, First myocardial infarction, Diabetes Mellitus, Non-Insulin-Dependent, Asthma and Cataract. The involved functions are known as Cell Survival, inhibitors, Process, Metabolic Inhibition and Oxidation. Myricetin often locates in Fibril - cell component, soluble, Body tissue, Back and Tissue membrane. The associated genes with myricetin are HPGDS gene, P4HTM gene, CFLAR gene, SLC2A2 gene and SLC2A1 gene. The related lipids are Promega, Sterols, dipalmitoylphosphatidylserine, 1,2-oleoylphosphatidylcholine and Membrane Lipids. 1801
kaempferol kaempferol is a lipid of Polyketides (PK) class. Kaempferol is associated with abnormalities such as Cardiovascular Diseases, IMMUNE SUPPRESSION, Inflammatory disorder, Dermatitis, Atopic and Asthma. The involved functions are known as enzyme activity, antagonists, DNA Binding, Anabolism and Transcription, Genetic. Kaempferol often locates in aryl hydrocarbon receptor complex, Cytoplasmic matrix, soluble, BL21 and Vacuole. The associated genes with kaempferol are CYP1A1 gene, AHR gene, Genes, Reporter, Candidate Disease Gene and Alleles. The related lipids are Fatty Acids, Steroids, Lipopolysaccharides, Total cholesterol and Palmitates. The related experimental models are Knock-out, Xenograft Model, Breast Cancer Model, Disease model and Animal Disease Models. 3675
quercetin quercetin is a lipid of Polyketides (PK) class. Quercetin is associated with abnormalities such as Coronary heart disease, Myocardial Infarction, Cirrhosis, Coronary Arteriosclerosis and Vascular ring. The involved functions are known as Vasodilation, physiological aspects, Fermentation, Process and Ingredient. Quercetin often locates in Arterial system, Endothelium, Skin, Endothelium, Vascular and Tissue specimen. The associated genes with quercetin are P4HTM gene, SULT gene, UGT1A1 gene, ARHGAP26 gene and PLXNB1 gene. The related lipids are blood lipid, Promega, Steroids, Phosphatidylserines and Fatty Acids. The related experimental models are Knock-out, Mouse Model, Xenograft Model, Tissue Model and Cancer Model. 5377
apigenin apigenin is a lipid of Polyketides (PK) class. Apigenin is associated with abnormalities such as Morphologically altered structure, Chimera disorder, Hypertensive disease, infection induced and Infection. The involved functions are known as inhibitors, Gene Expression, Process, Metabolic Inhibition and Cell Death. Apigenin often locates in Vacuole, Cytoplasmic matrix, Cytoplasm, Tissue membrane and Membrane. The associated genes with apigenin are MSMP gene, BCL2 gene, PTGS2 gene, Chromatin and SLC33A1 gene. The related lipids are Lipopolysaccharides, Steroids, 1-Butanol, agosterol A and Butyrates. The related experimental models are Mouse Model, Tissue Model, Knock-out, Xenograft Model and Disease model. 4250
luteolin luteolin is a lipid of Polyketides (PK) class. Luteolin is associated with abnormalities such as Morphologically altered structure, Nodule, retinal toxicity, CLEFT LIP, CONGENITAL HEALED and Ischemia. The involved functions are known as Metabolic Inhibition, Cell Death, Caspase Activation, activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway and protein kinase C activity. Luteolin often locates in Mitochondria, Cell-Free System, Protoplasm, Membrane and Body tissue. The associated genes with luteolin are BCL2 gene, TNFSF10 gene, BCL2L1 gene, XIAP gene and MCL1 gene. The related lipids are Lipopolysaccharides, Sterols, blood lipid, Fatty Acids and Steroids. The related experimental models are Xenograft Model, Mouse Model, Experimental Autoimmune Encephalomyelitis, Knock-out and Cancer Model. 3284
FLAVONE FLAVONE is a lipid of Polyketides (PK) class. Flavone is associated with abnormalities such as Cardiovascular Diseases, Cerebrovascular accident, DERMATITIS HERPETIFORMIS, FAMILIAL, Hyperinsulinism and Inflammatory disorder. The involved functions are known as Oxidation-Reduction, Metabolic Inhibition, Inflammation, Phosphorylation and antioxidant activity. Flavone often locates in Endothelium, Hepatic, Protoplasm, Body tissue and Extracellular. The associated genes with FLAVONE are ICAM1 gene, BCL2L1 gene, MYC gene, TP53 gene and cytochrome c''. The related lipids are Promega, Steroids and Total cholesterol. The related experimental models are Knock-out, Disease model and Animal Disease Models. 2093
Tricetin Tricetin is a lipid of Polyketides (PK) class. Tricetin is associated with abnormalities such as Diabetes. The involved functions are known as inhibitors, Inflammation and Chronic inflammation. Tricetin often locates in Blood. The related lipids are Lipopolysaccharides. 46
baicalein baicalein is a lipid of Polyketides (PK) class. Baicalein is associated with abnormalities such as Neurodegenerative Disorders, Fibrillation, Hypertensive disease, Aortic coarctation and Coronary Occlusion. The involved functions are known as Anabolism, Polymerization, Process, inhibitors and Pathogenesis. Baicalein often locates in Membrane, Lipid Bilayers, soluble, Cell-Free System and Protoplasm. The associated genes with baicalein are P4HTM gene, BIRC5 gene, TSPO gene, SHOC2 gene and XIAP gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, iodoresiniferatoxin, Lipopolysaccharides and 17-octadecynoic acid. The related experimental models are Knock-out, Mouse Model and Parkinsonism, Experimental. 1997
Oroxylin A Oroxylin A is a lipid of Polyketides (PK) class. 180
Wogonin Wogonin is a lipid of Polyketides (PK) class. Wogonin is associated with abnormalities such as Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and Ischemia. The involved functions are known as Inflammation, Regulation, luciferase activity, store-operated calcium entry and Transcriptional Activation. Wogonin often locates in Cytoplasmic matrix, Pore, Membrane, Protoplasm and Mitochondria. The associated genes with Wogonin are SGK1 gene, ORAI1 gene, STIM1 gene, P4HTM gene and BCL2 gene. 732
Nobiletin Nobiletin is a lipid of Polyketides (PK) class. Nobiletin is associated with abnormalities such as Hashimoto Disease, nervous system disorder, Dermatitis, Senile Plaques and Metabolic Diseases. The involved functions are known as 5-(carboxyamino)imidazole ribonucleotide mutase activity, Signal Transduction, Biochemical Pathway, Phosphorylation and MAP kinase kinase activity. Nobiletin often locates in Extracellular, Protoplasm, Back, Mouse Skin and Skin - Epidermis (MMHCC). The associated genes with Nobiletin are MAP2K1 gene, PTGS2 gene, Amyloid beta-Protein Precursor, Candidate Disease Gene and BCL2 gene. The related lipids are Lipopolysaccharides and Sterols. The related experimental models are Mouse Model and Transgenic Model. 550
Baohuoside 1 Baohuoside 1 is a lipid of Polyketides (PK) class. 130
isoliquiritigenin Isoliquiritigenin is a lipid of Polyketides (PK) class. Isoliquiritigenin is associated with abnormalities such as abnormal fragmented structure, Gastric ulcer, Gastric mucosa lesion, Peptic Ulcer and Wiskott-Aldrich Syndrome. The involved functions are known as Mass-to-Charge Ratio, Anabolism, Oxidation, inhibitors and Energy Absorption. Isoliquiritigenin often locates in Microsomes, Liver, Hepatic, Microsomes, Immune system and Vacuole. The associated genes with Isoliquiritigenin are P4HTM gene, BCL2 gene, AP1AR gene, oxytocin, 1-desamino-(O-Et-Tyr)(2)- and ODAM gene. The related experimental models are Knock-out. 220
Xanthohumol Xanthohumol is a lipid of Polyketides (PK) class. Xanthohumol is associated with abnormalities such as Endometriosis, site unspecified, Cyst, peritoneal lesion, Proliferative inflammation and furuncle. The involved functions are known as Cell Proliferation, Signal Transduction, Pathologic Neovascularization, Adverse effects and Proliferation (morphologic abnormality). Xanthohumol often locates in peritoneal, Mesentery, Membrane, Tissue specimen from uterus and Cell Nucleus. The associated genes with Xanthohumol are PI3 gene, KEAP1 gene, SLC33A1 gene, BCR-ABL Fusion Gene and BIRC5 gene. The related lipids are Fatty Acids and Palmitates. The related experimental models are Knock-out. 465
rottlerin Rottlerin is a lipid of Polyketides (PK) class. Rottlerin is associated with abnormalities such as PARAGANGLIOMAS 2, Hyperostosis, Diffuse Idiopathic Skeletal, Virus Diseases, Perisylvian syndrome and Autoimmune disease (systemic) NOS. The involved functions are known as Apoptosis, Regulation, Signal Transduction, inhibitors and Proteasome Inhibitors [MoA]. Rottlerin often locates in Clone, Membrane, Body tissue, Plasma membrane and soluble. The associated genes with Rottlerin are XIAP gene, GAPDH gene, ICAM1 gene, P4HTM gene and TNFSF10 gene. The related lipids are Promega, Fatty Acids, Sphingolipids, Lipopolysaccharides and Saponin. The related experimental models are Mouse Model, Xenograft Model and Cancer Model. 1198
phloretin phloretin is a lipid of Polyketides (PK) class. Phloretin is associated with abnormalities such as Atherosclerosis, Diabetes Mellitus, Non-Insulin-Dependent, Alkalemia, Renal tubular disorder and pathologic fistula. The involved functions are known as Anabolism, glycosyltransferase activity, Biosynthetic Pathways, Localized desquamation and Biological Processes. Phloretin often locates in soluble, BL21, Cytoplasmic, Extracellular and Cytoplasm. The associated genes with phloretin are Homologous Gene, CD36 gene, Candidate Disease Gene, SLC33A1 gene and PAK1IP1 gene. The related lipids are Liposomes, Palmitates, Fatty Acids, Sterols and 6-ketocholestanol. The related experimental models are Knock-out. 2367
naringenin naringenin is a lipid of Polyketides (PK) class. Naringenin is associated with abnormalities such as Dehydration, Papillon-Lefevre Disease, BOSLEY-SALIH-ALORAINY SYNDROME, Cardiovascular Diseases and Atherosclerosis. The involved functions are known as Pigmentation, Biosynthetic Pathways, metaplastic cell transformation, 4-coumarate-CoA ligase activity and Pigment. Naringenin often locates in Body tissue, Cell Wall, Membrane, Cytoplasmic matrix and Tissue membrane. The associated genes with naringenin are Genome, Genes, Regulator, Alleles, Homologous Gene and SPEN gene. The related lipids are Fatty Acids, Total cholesterol, Lipopolysaccharides, Oleates and Cholesterol, Dietary. The related experimental models are Knock-out and Mouse Model. 2420
hesperetin Hesperetin is a lipid of Polyketides (PK) class. Hesperetin is associated with abnormalities such as Corn of toe, Ischemia, Osteoporosis, Consumption-archaic term for TB and Wiskott-Aldrich Syndrome. The involved functions are known as conjugation, inhibitors, Process, mRNA Expression and Adjudication. Hesperetin often locates in Entire intestinal epithelium, Protoplasm, Membrane, Shoulder and Back. The associated genes with Hesperetin are ABCG2 gene, ABCC2 gene, FATE1 gene, ABCB1 gene and P-glycoprotein 2. 801
hesperidin (2S)-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-oxo-3,4-dihydro-2H-chromen-7-yl 6-O-(6-deoxyhexopyranosyl)hexopyranoside is a lipid of Polyketides (PK) class. (2s)-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-oxo-3,4-dihydro-2h-chromen-7-yl 6-o-(6-deoxyhexopyranosyl)hexopyranoside is associated with abnormalities such as Osteoporosis, Postmenopausal, estrogen deficiency, Chronic venous insufficiency, Neurodegenerative Disorders and Cerebrovascular accident. The involved functions are known as Sweetening Agents, Vmax, enzyme activity, Fermentation and Regulation. (2s)-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-oxo-3,4-dihydro-2h-chromen-7-yl 6-o-(6-deoxyhexopyranosyl)hexopyranoside often locates in Entire gastrointestinal tract, soluble, Entire bony skeleton, Trabecular substance of bone and Blood. The associated genes with (2S)-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-oxo-3,4-dihydro-2H-chromen-7-yl 6-O-(6-deoxyhexopyranosyl)hexopyranoside are MTPN gene, GLUCOSIDASE, STN gene, SLC33A1 gene and GHRL gene. The related lipids are Total cholesterol and blood lipid. The related experimental models are Arthritis, Collagen-Induced. 1455
hypericin hypericin is a lipid of Polyketides (PK) class. Hypericin is associated with abnormalities such as Dermatitis, Phototoxic, Dehydration, Photosensitization, Morphologically altered structure and Myocardial Infarction. The involved functions are known as Cell Cycle Checkpoints, Apoptosis, Acetylation, Cell Survival and Caspase Activation. Hypericin often locates in insoluble fraction, Cytoplasmic matrix, Protoplasm, Tissue membrane and Cytoplasm. The associated genes with hypericin are CDC37 gene, HSPA8 gene, RAF1 gene, cyclin H and FK228. The related lipids are Phosphatidylserines. 1752
Aloe-emodin Aloe-emodin is a lipid of Polyketides (PK) class. Aloe-emodin is associated with abnormalities such as Wiskott-Aldrich Syndrome. The involved functions are known as Anabolism, Phosphorylation, Signal Transduction, Cell Proliferation and Cell Survival. Aloe-emodin often locates in Body tissue, Cell Fraction, Mitochondria, Micronucleus and Microsomes, Liver. The associated genes with Aloe-emodin are MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 2, RICTOR gene, PI3 gene, PRR5 gene and MANEA gene. 451
emodin emodin is a lipid of Polyketides (PK) class. Emodin is associated with abnormalities such as Infection, Conjunctivitis, Vernal, Stevens-Johnson Syndrome, Conjunctival scar and Allergic Conjunctivitis. The involved functions are known as signaling cascade, Metabolic Inhibition, Cell Death, Phosphorylation and JNK Pathway. Emodin often locates in Membrane, Protoplasm, Mitochondria, Cytoplasmic matrix and soluble. The associated genes with emodin are cytochrome c'', UTS2 gene, TK Gene, Gene Clusters and CFC1 gene. The related lipids are Phosphatidylserines, Promega, Sphingolipids, Membrane Lipids and Palmitates. The related experimental models are Mouse Model and Transgenic Model. 1742
Rhein Rhein is a lipid of Polyketides (PK) class. Rhein is associated with abnormalities such as Obesity, Non-alcoholic Fatty Liver Disease, Dyslipidemias, Fatty Liver and Degenerative polyarthritis. The involved functions are known as Adipogenesis, Insulin Resistance, luciferase activity, Transcription, Genetic and Inflammation. Rhein often locates in Hepatic, Brown Fat, Muscle, Mouse Liver and Mitochondria. The associated genes with Rhein are QRSL1 gene, Candidate Disease Gene, CFB gene, STAT6 gene and GATA3 gene. The related lipids are Fatty Acids. 986
doxorubicin Adriamycin is a lipid of Polyketides (PK) class. Adriamycin is associated with abnormalities such as Cardiomyopathies. The involved functions are known as Transcription, Genetic, Process, Drug effect disorder, Diastasis and Oxidation-Reduction. Adriamycin often locates in Muscle, Myocardium and Entire gastrointestinal tract. 54913
Fluoxymesterone Fluoxymesterone is a lipid of Sterol Lipids (ST) class. Fluoxymesterone is associated with abnormalities such as Anemia. The involved functions are known as Stimulus. Fluoxymesterone often locates in Entire bony skeleton. 280
(-)-Perillyl alcohol (-)-perillyl alcohol is a lipid of Prenol Lipids (PR) class. The involved functions are known as Cell Cycle Progression, Cell Cycle, Cell Proliferation, Apoptosis and Isoprenylation. (-)-perillyl alcohol often locates in Cytoplasm, Membrane and Plasma membrane. The associated genes with (-)-Perillyl alcohol are JUN gene, Candidate Disease Gene, IL24 gene, BCL2L1 gene and CFB gene. The related experimental models are Transgenic Model. 299
(+)-Camphor (+)-camphor is a lipid of Prenol Lipids (PR) class. (+)-camphor is associated with abnormalities such as Athetoid cerebral palsy. The involved functions are known as inhibitors, Synthesis, Feedback and Competitive inhibition. The associated genes with (+)-Camphor are 4S-limonene synthase. The related lipids are palmitoleic acid, pentadecanoic acid, stearic acid and erucic acid. 3660
2E,6E-farnesol 2e,6e-farnesol is a lipid of Prenol Lipids (PR) class. 2e,6e-farnesol is associated with abnormalities such as Granulomatous Disease, Chronic, pathologic fistula and Cavitation. The involved functions are known as Regulation, Metabolic Inhibition, cholesterol biosynthetic process, Process and Transcription, Genetic. 2e,6e-farnesol often locates in Plasma membrane, Cytoplasmic matrix, cornified envelope, Epidermis and peroxisome. The associated genes with 2E,6E-farnesol are RAB3A gene, FOSL1 gene, CASP8AP2 gene, RCC1 gene and GALE gene. The related lipids are Sterols, Membrane Lipids and Steroids. 1905
Farnesyl diphosphate Farnesyl diphosphate is a lipid of Prenol Lipids (PR) class. Farnesyl diphosphate is associated with abnormalities such as Dental caries and Hyperostosis, Diffuse Idiopathic Skeletal. The involved functions are known as Regulation, Process, Signal, Anabolism and inhibitors. Farnesyl diphosphate often locates in peroxisome, Cytoplasmic matrix, Plasma membrane, soluble and Mitochondria. The associated genes with Farnesyl diphosphate are HSD3B1 gene, ABRA gene, MATN1 gene, SEPSECS gene and MBD2 gene. The related lipids are Sterols, 22-hydroxycholesterol, dehydrosqualene, SK&F 104976 and 25-hydroxycholesterol. 1181
(e,z)-farnesol (e,z)-farnesol is a lipid of Prenol Lipids (PR) class. 1183
(z,z)-farnesol (z,z)-farnesol is a lipid of Prenol Lipids (PR) class. 1183
Geranylgeranyl diphosphate Geranylgeranyl diphosphate is a lipid of Prenol Lipids (PR) class. The involved functions are known as RNA Interference, Anabolism, Cytokinesis, Gene Expression and physiological aspects. Geranylgeranyl diphosphate often locates in soluble, Skeletal system, Cell-Free System, Plasma membrane and soluble fraction. The associated genes with Geranylgeranyl diphosphate are Genome, IMPACT gene, Open Reading Frames, Gene Clusters and Genes, Regulator. The related lipids are Fatty Acids, Sterols, terpentetriene and Membrane Lipids. 885
Geranylgeraniol Geranylgeraniol is a lipid of Prenol Lipids (PR) class. Geranylgeraniol is associated with abnormalities such as abnormal fragmented structure, Hyperostosis, Diffuse Idiopathic Skeletal and Tuberculosis. The involved functions are known as Positive Regulation of Apoptosis, Anabolism, Prenylation, Apoptosis and pathologic cytolysis. Geranylgeraniol often locates in Body tissue, Cytoplasmic matrix, Red Cell Ghost, Spindle and Nuclear lamin. The associated genes with Geranylgeraniol are MST1 gene, STN gene, UMOD gene, ABCA1 gene and RHOA gene. The related lipids are Sterols, Hydroxycholesterols, SK&F 104976 and 25-hydroxycholesterol. 403
fumagillin Fumagillin is a lipid of Prenol Lipids (PR) class. Fumagillin is associated with abnormalities such as Atherosclerosis, Dentatorubral-Pallidoluysian Atrophy, Severe Combined Immunodeficiency, Immunologic Deficiency Syndromes and Arthritis. The involved functions are known as Gene Expression, Apoptosis, Angiogenic Process, Infiltration and Adverse effects. Fumagillin often locates in Endothelium, Body tissue, Blood, soluble and Protoplasm. The associated genes with fumagillin are HIST1H1C gene, RAC1 gene, c-myb Genes, METAP2 gene and NCKIPSD gene. The related lipids are helvolic acid, Butyrates and Butanols. The related experimental models are Mouse Model, Xenograft Model and Cancer Model. 500
Deoxyelephantopin Deoxyelephantopin is a lipid of Prenol Lipids (PR) class. 38
Alpha-humulene Alpha-humulene is a lipid of Prenol Lipids (PR) class. 155
Gossypol Gossypol is a lipid of Prenol Lipids (PR) class. Gossypol is associated with abnormalities such as Paralytic Ileus, PARKINSON DISEASE, LATE-ONSET, Fibrillation, Hepatic necrosis and Lymphopenia. The involved functions are known as Atrophic, Ulcer, Necrosis, Apoptosis and antagonists. Gossypol often locates in Mucous Membrane, Epithelium, Blood, Microsomes, Liver and Autophagic vacuole. The associated genes with Gossypol are BCL2A1 gene, BCL2 gene, Transgenes, IGH@ gene cluster and Bax protein (53-86). The related lipids are Promega, proteoliposomes, Phosphatidylserines and Liposomes. The related experimental models are Transgenic Model and Xenograft Model. 2557
Thapsigargin Thapsigargin is a lipid of Prenol Lipids (PR) class. Thapsigargin is associated with abnormalities such as Impaired glucose tolerance, Obesity and Blood Pressure Disorders. The involved functions are known as Phosphorylation, establishment and maintenance of localization, Regulation, Metabolic Inhibition and Proteolysis. Thapsigargin often locates in Mouse Skin, Cytoplasm, Skin, Protoplasm and Mitochondria. The associated genes with Thapsigargin are ERBB4 gene, F11 gene, CA1 gene, TRNAP1 gene and HSPA5 gene. The related lipids are taurolithocholic acid 3-sulfate, Liposomes, Fatty Acids and stearylamine. The related experimental models are Mouse Model. 8868
Crocetin Crocetin is a lipid of Prenol Lipids (PR) class. Crocetin is associated with abnormalities such as abnormal fragmented structure, Gout, Infection and athymia. The involved functions are known as Cytokinesis, Anabolism, enzyme mechanism, Pathological accumulation of air in tissues and Hemorrhage. Crocetin often locates in Vacuole, Cytoplasmic matrix, Body tissue, Mitochondria and Blood. The associated genes with Crocetin are cytochrome c'', BCL2 gene and PCNA gene. The related lipids are mycorradicin. 350
forskolin Forskolin is a lipid of Prenol Lipids (PR) class. Forskolin is associated with abnormalities such as Cholestasis, Vocal cord dysfunction familial, Hypothyroidism, Renal tubular disorder and Disintegration (morphologic abnormality). The involved functions are known as Cell Proliferation, Anabolism, mRNA Expression, Agent and Signal. Forskolin often locates in Extracellular, Body tissue, Skin, Tissue membrane and Membrane. The associated genes with forskolin are P4HTM gene, SLC33A1 gene, NR1I2 gene, Genes, Reporter and CYP3A gene. The related lipids are Steroids, steroid sulfate, Fatty Acids, LYSO-PC and Lipopolysaccharides. 24755
Phorbol Phorbol is a lipid of Prenol Lipids (PR) class. Phorbol is associated with abnormalities such as furuncle, Infection, endothelial dysfunction, Morphologically altered structure and Acute erythroleukemia. The involved functions are known as Tyrosine Phosphorylation, Metabolic Inhibition, Transcription, Genetic, Protein Biosynthesis and Signal. Phorbol often locates in Tissue membrane, Membrane, Cell surface, soluble and Cytoplasmic Domain. The associated genes with Phorbol are STAT3 gene, JAK2 gene, JUN gene, PROC gene and MAPK8 gene. The related lipids are Lipopolysaccharides, Phosphatidylserines, Liposomes, Fatty Acids and Octanols. 2082
phorbol 13-acetate 12-myristate Phorbol 13-acetate 12-myristate is a lipid of Prenol Lipids (PR) class. The involved functions are known as DNA Fragmentation, Phosphorylation and Irritation. Phorbol 13-acetate 12-myristate often locates in low-density lipoprotein particle. The associated genes with phorbol 13-acetate 12-myristate are FPR1 gene and ABCB1 gene. 40921
Sphingosine 1-phosphate Sphingosine 1-phosphate is a lipid of Sphingolipids (SP) class. Sphingosine 1-phosphate is associated with abnormalities such as Infection, Painful Bladder Syndrome, Atherosclerosis, Hyperglycemia and Rheumatoid Arthritis. The involved functions are known as Phosphorylation, Regulation, enzyme activity, Energy Absorption and Vascular Permeability. Sphingosine 1-phosphate often locates in Endothelium, Tissue membrane, Vascular System, Protoplasm and Microfilaments. The associated genes with Sphingosine 1-phosphate are MBTPS1 gene, FBXL15 gene, TEK gene, NTRK1 gene and Gene Family. The related lipids are Promega, Lipopolysaccharides, lysophosphatidic acid, Lysophosphatidylcholines and Lysophospholipids. The related experimental models are Knock-out, Mouse Model, Transgenic Model, Disease model and Experimental Autoimmune Encephalomyelitis. 2005
N,N-dimethylsphingosine N,N-dimethylsphingosine is a lipid of Sphingolipids (SP) class. N,n-dimethylsphingosine is associated with abnormalities such as Exanthema and Increased drug resistance. The involved functions are known as Vmax, Metabolic Inhibition, Anabolism, Binding (Molecular Function) and Cytokinesis. N,n-dimethylsphingosine often locates in yolk, Membrane, CNS - Brain (MMHCC), soluble and Tissue membrane. The associated genes with N,N-dimethylsphingosine are FPR1 gene, ANP32A gene, HPGDS gene, Nuclear phosphoprotein and PTGS2 gene. The related lipids are Sphingolipids, Phosphatidic Acid, Lysophosphatidylcholines, stearylamine and dihydroceramide. The related experimental models are Mouse Model and Knock-out. 151
fumonisin b1 fumonisin b1 is a lipid of Sphingolipids (SP) class. Fumonisin b1 is associated with abnormalities such as Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL and Malnutrition. The involved functions are known as Gene Expression, Anabolism, Signal, Biosynthetic Pathways and Regulation. Fumonisin b1 often locates in Body tissue, Microsomes, microsomal membrane, Protoplasm and Mitochondria. The associated genes with fumonisin b1 are Genome, P4HTM gene, FATE1 gene, BCL2 gene and TMEM132D gene. The related lipids are dihydroceramide, ceramide 1-phosphate, Sphingolipids, Fatty Acids and Palmitates. 902
N-Palmitoylsphingosine N-Palmitoylsphingosine is a lipid of Sphingolipids (SP) class. The involved functions are known as ceramide biosynthetic process, Apoptosis, Regulation, Signal Transduction and Caspase-Dependent Apoptosis. N-palmitoylsphingosine often locates in Mitochondria, Membrane, Extracellular and Endoplasmic Reticulum. The associated genes with N-Palmitoylsphingosine are BCL2 gene, cytochrome c'', BCL2L1 gene, LASS6 gene and LASS5 gene. The related lipids are dihydroceramide, Fatty Acids, Sphingolipids, Palmitates and inositolphosphorylceramide. 71
cholesterol cholesterol is a lipid of Sterol Lipids (ST) class. Cholesterol is associated with abnormalities such as Trypanosomiasis, Chagas Disease, Cleft Palate, Chondrodysplasia punctata 2, X-linked dominant and Child syndrome. The involved functions are known as Blood Circulation, Sterol Biosynthesis Pathway, Receptor Mediated Endocytosis, Methylation and Signal. Cholesterol often locates in Animal tissue, Blood, Membrane, Plasma membrane and peroxisome. The associated genes with cholesterol are MBD2 gene, SIM, SLC33A1 gene, Genome and NSDHL gene. The related lipids are Sterols, zymosterol, fecosterol, Total cholesterol and 7-dehydrocholesterol. The related experimental models are Mouse Model, Knock-out, Genetically Engineered Mouse and Disease model. 98461
Taurodeoxycholic acid Taurodeoxycholic acid is a lipid of Sterol Lipids (ST) class. Taurodeoxycholic acid is associated with abnormalities such as Ischemia and Wiskott-Aldrich Syndrome. The involved functions are known as Cell Proliferation, Transcriptional Activation, Phosphorylation, Anabolism and Biochemical Pathway. Taurodeoxycholic acid often locates in Body tissue, Epithelium, Blood, Mucous Membrane and Hepatic. The associated genes with Taurodeoxycholic acid are NOX5 gene, GPBAR1 gene, NR1H4 gene and SLC33A1 gene. The related lipids are cholanic acid, taurolithocholic acid 3-sulfate, Sterols, 7-dehydrocholesterol and tauromuricholic acid. 352
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