Disease MeSH term: Diabetes Mellitus, Type 2

Possible associated with:

Structure name description Reference count
acetic acid acetic acid is a lipid of Fatty Acyls (FA) class. Acetic acid is associated with abnormalities such as Vitamin B 12 Deficiency. The involved functions are known as Excretory function. The related lipids are Propionate. 89633
butyric acid butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid. 9358
stearic acid stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out. 5692
Lignoceric acid Lignoceric acid is a lipid of Fatty Acyls (FA) class. Lignoceric acid is associated with abnormalities such as Adrenoleukodystrophy and Peroxisomal Disorders. The involved functions are known as Anabolism, establishment and maintenance of localization, Saturated, Process and long-chain-fatty-acid-CoA ligase activity. Lignoceric acid often locates in Membrane, Microsomes, Plasma membrane, peroxisome and Mitochondria. The associated genes with Lignoceric acid are SLC27A1 gene, CD36 gene, F10 gene, INHA gene and ABCD1 gene. The related lipids are Sphingolipids, Fatty Acids, erucic acid, inositolphosphoceramides and Palmitates. 337
4-METHYLPENTANOIC ACID 4-METHYLPENTANOIC ACID is a lipid of Fatty Acyls (FA) class. The involved functions are known as CoA-transferase activity. 4-methylpentanoic acid often locates in Cytosol. The related lipids are Fatty Acids and alpha-ketocaproic acid. 126
Arachidonic acid Arachidonic acid is a lipid of Fatty Acyls (FA) class. Arachidonic acid is associated with abnormalities such as Atherosclerosis, Ischemia, Hypertensive disease, Hypertension induced by pregnancy and Vascular ring of aorta. The involved functions are known as Platelet aggregation, Anabolism, Ion Transport, Signal Transduction Pathways and Signal. Arachidonic acid often locates in Extracellular, Body tissue, Protoplasm, Tissue membrane and soluble. The associated genes with Arachidonic acid are CYP2J2 gene, CYP2E1 gene, Recombinant Proteins, POR gene and P4HTM gene. The related lipids are Fatty Acids, Glycerophospholipids, Steroids, octadecadienoic acid and 9-hydroxy-10,12-octadecadienoic acid. The related experimental models are Mouse Model and Knock-out. 22864
cis-9-palmitoleic acid Cis-9-palmitoleic acid is a lipid of Fatty Acyls (FA) class. 694
trans-9-palmitoleic acid Trans-9-palmitoleic acid is a lipid of Fatty Acyls (FA) class. 468
Linoleic acid Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids. 5699
Linoelaidic acid Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone. 10058
bishomo-gamma-linolenic acid Bishomo-gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. Bishomo-gamma-linolenic acid is associated with abnormalities such as Diabetes, Obesity, Hypertensive disease, Cirrhosis and Hepatorenal Syndrome. The involved functions are known as Oxidation, Process, Metabolic Inhibition, epoxide hydrolase activity and Signal Transduction Pathways. Bishomo-gamma-linolenic acid often locates in Protoplasm, Cytoplasmic matrix, soluble, Membrane and Tissue membrane. The associated genes with bishomo-gamma-linolenic acid are P4HTM gene, IMPACT gene, arginine methyl ester, CYP gene and PTGS1 gene. The related lipids are Fatty Acids, 17-octadecynoic acid, Lipopolysaccharides, palmitoleic acid and nervonic acid. The related experimental models are Knock-out and Mouse Model. 2467
gamma-Linolenic acid Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system. 1919
alpha-linolenic acid Alpha-linolenic acid is a lipid of Fatty Acyls (FA) class. Alpha-linolenic acid is associated with abnormalities such as Coronary heart disease, abnormal fragmented structure, Arterial thrombosis and Subarachnoid Hemorrhage. The involved functions are known as Anabolism, Signal, Transcription, Genetic, Saturated and Regulation. Alpha-linolenic acid often locates in Blood, Body tissue, Plasma membrane, Hepatic and peroxisome. The associated genes with alpha-linolenic acid are FATE1 gene, volicitin, CYP2U1 gene, CYP1A2 gene and CYP2J2 gene. The related lipids are Fatty Acids, Dietary Fatty Acid, stearidonic acid and Fatty Acids, Nonesterified. 4231
beta-parinaric acid Beta-parinaric acid is a lipid of Fatty Acyls (FA) class. 416
Alpha-parinaric acid Alpha-parinaric acid is a lipid of Fatty Acyls (FA) class. 226
DHA Dha is a lipid of Fatty Acyls (FA) class. Dha is associated with abnormalities such as Atherosclerosis, Consumption-archaic term for TB, Chronic disease, Cardiovascular Diseases and Diabetes Mellitus, Non-Insulin-Dependent. The involved functions are known as Inflammation, Oxidation, fatty acid oxidation, Fatty Acid Metabolism and Lipid Metabolism. Dha often locates in Hepatic, Protoplasm, Mucous Membrane, Epithelium and outer membrane. The associated genes with DHA are IMPACT gene, FATE1 gene, GAPDH gene, THOC4 gene and SLC33A1 gene. The related lipids are stearidonic acid, Fatty Acids, Total cholesterol, Lipopolysaccharides and Dietary Fatty Acid. The related experimental models are Mouse Model, Transgenic Model, Animal Disease Models and Arthritis, Experimental. 11054
7-octadecynoic acid 7-octadecynoic acid is a lipid of Fatty Acyls (FA) class. 8379
EPA Epa is a lipid of Fatty Acyls (FA) class. 5952
(+/-)alpha-hydoxy butyric acid (+/-)alpha-hydoxy butyric acid is a lipid of Fatty Acyls (FA) class. 390
(r)-3-hydroxybutanoic acid (r)-3-hydroxybutanoic acid is a lipid of Fatty Acyls (FA) class. 2710
3-hydroxybutyric acid 3-hydroxybutyric acid is a lipid of Fatty Acyls (FA) class. 3-hydroxybutyric acid is associated with abnormalities such as Ketosis. The involved functions are known as fatty acid oxidation, Oxidation, Synthesis, inhibitors and glucose metabolism. 3-hydroxybutyric acid often locates in Blood, Adipose tissue, Protoplasm, Hepatic and Extracellular. The associated genes with 3-hydroxybutyric acid are Genes, Developmental and Oncogene, RET. The related lipids are Fatty Acids, Nonesterified, 6-hydroxyhexanoate, tributyrin, 3-Hydroxyvalerate and Valerates. 4735
Acetoacetic acid Acetoacetic acid is a lipid of Fatty Acyls (FA) class.Acetoacetic acid is associated with abnormalities such as Dehydration. The involved functions are known as Biochemical Reaction, intracellular signal transduction, fatty acid elongation, Cytokinesis and Mass-to-Charge Ratio. The associated genes with Acetoacetic acid are CFB gene and mersacidin. Acetoacetic acidis associated with Carbon, Acids, Potassium, Acetoacetic acid and Oximes. The related lipids are Nonesterified Fatty Acids and Stearates. 2523
Pyruvic acid Pyruvic acid is a lipid of Fatty Acyls (FA) class. 27047
2,5-diaminopentanoic acid 2,5-diaminopentanoic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Vasodilation, Intestinal Absorption and Pinocytosis. 2,5-diaminopentanoic acid often locates in Mitochondria, Microfilaments, NADH dehydrogenase complex and respiratory chain complex III location sensu Eukarya. The associated genes with 2,5-diaminopentanoic acid are GAPDH gene and iberiotoxin. 8868
Lipoic acid Lipoic acid is a lipid of Fatty Acyls (FA) class. 7940
Aminoadipic acid Aminoadipic acid is a lipid of Fatty Acyls (FA) class. Aminoadipic acid is associated with abnormalities such as Diabetes and Proliferative retinopathy NOS. The involved functions are known as Uptake, Process, lysine catabolism, Pressure- physical agent and Proteolysis. Aminoadipic acid often locates in Protoplasm, Chromosomes, Astrocytic, Basal lamina and Cytoplasmic matrix. The associated genes with Aminoadipic acid are Homologous Gene, Excitatory Amino Acids, allysine, Diaminopimelic Acid and Gene Clusters. 1114
Methylmalonic acid Methylmalonic acid is a lipid of Fatty Acyls (FA) class. Methylmalonic acid is associated with abnormalities such as Vitamin B 12 Deficiency, Osteoporosis, Anemia, Anemia, Megaloblastic and Renal impairment. The involved functions are known as Abnormal renal function, Lactation, physiological aspects, phosphoglycerate dehydrogenase activity and Excretory function. Methylmalonic acid often locates in Entire bony skeleton, Blood, Protoplasm, Muscle and Body tissue. The associated genes with Methylmalonic acid are IMPACT gene, ACSF3 gene, CBLC gene, MMADHC gene and LMBRD1 gene. The related lipids are Fatty Acids and Butanols. 3174
9-HODE 9-hode is a lipid of Fatty Acyls (FA) class. 9-hode is associated with abnormalities such as Atherosclerosis, Chronic disease and Rheumatoid Arthritis. The involved functions are known as Oxidation, Transcriptional Activation, Esthesia, Signal Transduction and Process. 9-hode often locates in viral nucleocapsid location, Blood, Body tissue, Protoplasm and Lysosomal. The associated genes with 9-HODE are CD1A gene, CD276 Antigen, CD14 gene, IMPACT gene and GPR132 gene. The related lipids are Fatty Acids, 9-hydroxy-10,12-octadecadienoic acid, Nonesterified Fatty Acids, octadecadienoic acid and Total cholesterol. 200
Prostaglandin E2 Prostaglandin E2 is a lipid of Fatty Acyls (FA) class. Prostaglandin e2 is associated with abnormalities such as Renal glomerular disease, Arthritis, Degenerative polyarthritis, Pancreatitis and Rheumatoid Arthritis. The involved functions are known as enzyme pathway, Atherogenesis, Anabolism, inhibitors and Oxidants. Prostaglandin e2 often locates in Tissue membrane, Blood, Extracellular, Membrane and Protoplasm. The associated genes with Prostaglandin E2 are PTGS2 gene, TP53 gene, TNFRSF5 gene, FASTK Gene and TNF gene. The related lipids are Lipopolysaccharides, Steroids, monooxyethylene trimethylolpropane tristearate, Fatty Acids, Unsaturated and Promega. The related experimental models are Arthritis, Adjuvant-Induced, Xenograft Model, Experimental Autoimmune Encephalomyelitis, Cancer Model and Knock-out. 49278
11beta-PGF2 11beta-pgf2 is a lipid of Fatty Acyls (FA) class. 15009
15-F2t-IsoP 15-f2t-isop is a lipid of Fatty Acyls (FA) class. 15-f2t-isop is associated with abnormalities such as Diabetes Mellitus, Acute coronary syndrome, Risk factor, cardiovascular, thrombocytosis and Chronic ischemic heart disease NOS. The involved functions are known as Anabolism, Inflammation, Lipid Peroxidation, Excretory function and Platelet Activation. The associated genes with 15-F2t-IsoP are PTGS2 gene. 2120
Thromboxane b2 Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele. 10175
11-dehydro-TXB2 11-dehydro-txb2 is a lipid of Fatty Acyls (FA) class. 11-dehydro-txb2 is associated with abnormalities such as endothelial dysfunction, Risk factor, cardiovascular, Acute coronary syndrome, thrombocytosis and Chronic ischemic heart disease NOS. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and Lipid Peroxidation. The associated genes with 11-dehydro-TXB2 are PTGS2 gene. 381
11-dehydro-txb2 98
2,3-dinor, 6-keto-PGF1alpha 2,3-dinor, 6-keto-pgf1alpha is a lipid of Fatty Acyls (FA) class. 347
PGF1alpha Pgf1alpha is a lipid of Fatty Acyls (FA) class. 418
Leukotriene b4 Leukotriene b4 is a lipid of Fatty Acyls (FA) class. The involved functions are known as Chemotaxis, release of sequestered calcium ion into cytoplasm and Polymerization. Leukotriene b4 often locates in Protoplasm. The associated genes with Leukotriene b4 are phallacidin. 9311
Thromboxane a2 Thromboxane a2 is a lipid of Fatty Acyls (FA) class. Thromboxane a2 is associated with abnormalities such as Asthma, Cardiovascular Diseases, Pulmonary Eosinophilia, ASPIRIN SENSITIVITY and Pneumonia. The involved functions are known as Signal Transduction, paracrine, Binding (Molecular Function), Platelet Activation and Inflammation. Thromboxane a2 often locates in Cell surface, Body tissue, Cell membrane, Blood and Extracellular. The associated genes with Thromboxane a2 are PTPRC gene, ESAM gene and PPBP gene. 4534
Lipoxin A4 Lipoxin a4 is a lipid of Fatty Acyls (FA) class. Lipoxin a4 is associated with abnormalities such as Asthma, Cystic Fibrosis, Pneumonia, Obesity and Septicemia. The involved functions are known as Inflammation, Signal, Signal Transduction, Regulation and Metabolic Inhibition. Lipoxin a4 often locates in Immune system, Blood, soluble, Extracellular and Splenic Tissue. The associated genes with Lipoxin A4 are FPR2 gene, Homologous Gene, SAA1 gene, Trp-Lys-Tyr-Met-Val-Met and Annexin 1. The related lipids are Steroids. The related experimental models are Knock-out. 1240
15-epi-lxa4;15r-lxa4 15-epi-lxa4;15r-lxa4 is a lipid of Fatty Acyls (FA) class. 15-epi-lxa4;15r-lxa4 is associated with abnormalities such as Pneumonia, Septicemia, Cystic Fibrosis, Subarachnoid Hemorrhage and Obesity. The involved functions are known as Protective Agents, Signal Transduction, cytokine biosynthesis, Inflammation and Anabolism. 15-epi-lxa4;15r-lxa4 often locates in Blood, Immune system and Heart tissue. The associated genes with 15-epi-lxa4;15r-lxa4 are IL2 gene, CXCL13 gene and CMKLR1 gene. The related lipids are Steroids. The related experimental models are Knock-out. 305
15S-HETE 15s-hete is a lipid of Fatty Acyls (FA) class. 15s-hete is associated with abnormalities such as Ischemia and Vascular Diseases. The involved functions are known as Transcription, Genetic, Signal Transduction, tube formation, Angiogenic Process and Biochemical Pathway. 15s-hete often locates in Endothelium, Membrane, Cytoplasm, Body tissue and Protoplasm. The associated genes with 15S-HETE are RAC1 gene, ALOX15 gene, ALOX5 gene, Candidate Disease Gene and GAPDH gene. 1011
20-HETE 20-hete is a lipid of Fatty Acyls (FA) class. 20-hete is associated with abnormalities such as Cyst, Kidney Diseases, Kidney Failure, Chronic, Cystic Kidney Diseases and Simple renal cyst. The involved functions are known as Phosphorylation, inhibitors, Hypertrophy, Epithelial Cell Proliferation and Anabolism. 20-hete often locates in Mouse Kidney, Microsomes, Tissue membrane, Body tissue and Cytoplasmic matrix. The associated genes with 20-HETE are CYP4F3 gene, PKHD1 gene, Transgenes, P4HTM gene and CYP2E1 gene. The related lipids are Promega, enterodiol, Fatty Acids, hexanoic acid and U 73343. The related experimental models are Mouse Model, Knock-out, Streptozotocin Diabetes, Transgenic Model and Rodent Model. 1257
Coenzyme Q10 Coenzyme q10 is a lipid of Prenol Lipids (PR) class. Coenzyme q10 is associated with abnormalities such as Nephrotic Syndrome, Diabetes, COENZYME Q10 DEFICIENCY, Deafness and Hypertensive disease. The involved functions are known as Mutation, Process, Oxidation, Electron Transport and Oxidants. Coenzyme q10 often locates in Mitochondria, soluble, Plasma membrane, Body tissue and Inner mitochondrial membrane. The associated genes with Coenzyme Q10 are MT-CYB gene, ATP5B gene, cytochrome c'', STN gene and NPC1 gene. The related lipids are Total cholesterol and Lipid Peroxides. The related experimental models are Mouse Model. 4537
12S-HpETE 12s-hpete is a lipid of Fatty Acyls (FA) class. 211
12-hete 12-hete is a lipid of Fatty Acyls (FA) class. 1452
8-iso-PGE2 8-iso-pge2 is a lipid of Fatty Acyls (FA) class. 125
4-hydroxynonenal 4-hydroxynonenal is a lipid of Fatty Acyls (FA) class. 4-hydroxynonenal is associated with abnormalities such as Chronic disease, Obesity, Diabetes, Acquired Immunodeficiency Syndrome and Lung diseases. The involved functions are known as protein expression, Glycolysis, mRNA Expression, Regulation and Mitochondrion in division. 4-hydroxynonenal often locates in Muscle, Mitochondria, Adipose tissue, Head and Mouse Muscle. The associated genes with 4-hydroxynonenal are STAT3 gene, SIRT1 gene, PGC gene, IL6 gene and cytochrome c''. The related lipids are Lipopolysaccharides, Lipid Peroxides, Promega, Membrane Lipids and oxidized lipid. The related experimental models are Mouse Model, Knock-out, Transgenic Model, Disease model and Rodent Model. 5685
HMG-CoA Hmg-coa is a lipid of Fatty Acyls (FA) class. Hmg-coa is associated with abnormalities such as Cardiovascular Diseases, Hypercholesterolemia, Metabolic Diseases, Hyperhomocysteinemia and Morphologically altered structure. The involved functions are known as ketone body biosynthetic process, Regulation, Mutation, enzyme activity and HMG-CoA synthase activity. Hmg-coa often locates in Mitochondria, Cytoplasmic matrix, Hepatic, Membrane and Flank (surface region). The associated genes with HMG-CoA are Human gene, HMGCS2 gene, PPARA gene, ACSL1 Gene and Candidate Disease Gene. The related lipids are Fatty Acids, Sterols, Dehydrocholesterols, Lipopolysaccharides and 7-dehydrocholesterol. 355
Lmfa07050031 Lmfa07050031 is a lipid of Fatty Acyls (FA) class. The involved functions are known as Pigment and Polymerization. The related lipids are Propionate. 787
Malonyl-coa 492
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