Disease MeSH term: Diabetes Mellitus, Experimental

Possible associated with:

Structure name description Reference count
acetic acid acetic acid is a lipid of Fatty Acyls (FA) class. Acetic acid is associated with abnormalities such as Vitamin B 12 Deficiency. The involved functions are known as Excretory function. The related lipids are Propionate. 89633
octanoic acid octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid. 3349
lauric acid lauric acid is a lipid of Fatty Acyls (FA) class. Lauric acid is associated with abnormalities such as Infection, Renal tubular disorder, Hypertensive disease, Obesity and Mycoses. The involved functions are known as Transcription, Genetic, Signal Transduction, Mutation, metaplastic cell transformation and Anabolism. Lauric acid often locates in Skin, Plasma membrane, Cytoplasmic matrix, Body tissue and Palmar surface. The associated genes with lauric acid are Gene Family, SLC33A1 gene, Homologous Gene, Open Reading Frames and P4HTM gene. The related lipids are Fatty Acids, Oleic Acids, Palmitates, Stearates and 9,11-linoleic acid. 3691
Arachidonic acid Arachidonic acid is a lipid of Fatty Acyls (FA) class. Arachidonic acid is associated with abnormalities such as Atherosclerosis, Ischemia, Hypertensive disease, Hypertension induced by pregnancy and Vascular ring of aorta. The involved functions are known as Platelet aggregation, Anabolism, Ion Transport, Signal Transduction Pathways and Signal. Arachidonic acid often locates in Extracellular, Body tissue, Protoplasm, Tissue membrane and soluble. The associated genes with Arachidonic acid are CYP2J2 gene, CYP2E1 gene, Recombinant Proteins, POR gene and P4HTM gene. The related lipids are Fatty Acids, Glycerophospholipids, Steroids, octadecadienoic acid and 9-hydroxy-10,12-octadecadienoic acid. The related experimental models are Mouse Model and Knock-out. 22864
cis-erucic acid Cis-erucic acid is a lipid of Fatty Acyls (FA) class. 251
Rumenic acid Rumenic acid is a lipid of Fatty Acyls (FA) class. Rumenic acid is associated with abnormalities such as Atherosclerosis, Vascular lesions, Hyperlipidemia and Consumption-archaic term for TB. The involved functions are known as Fatty streaks, Transcriptional Activation, Atherogenesis, cholesterol transport and ATP binding. Rumenic acid often locates in Blood and Body tissue. The associated genes with Rumenic acid are ABCA1 gene, apolipoprotein SAA, FATE1 gene and TFCP2 gene. The related lipids are 9,11-linoleic acid, (E,Z)-isomer, 9,11-linoleic acid, Fatty Acids, 11-octadecenoic acid and Total cholesterol. 324
gamma-Linolenic acid Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system. 1919
alpha-linolenic acid Alpha-linolenic acid is a lipid of Fatty Acyls (FA) class. Alpha-linolenic acid is associated with abnormalities such as Coronary heart disease, abnormal fragmented structure, Arterial thrombosis and Subarachnoid Hemorrhage. The involved functions are known as Anabolism, Signal, Transcription, Genetic, Saturated and Regulation. Alpha-linolenic acid often locates in Blood, Body tissue, Plasma membrane, Hepatic and peroxisome. The associated genes with alpha-linolenic acid are FATE1 gene, volicitin, CYP2U1 gene, CYP1A2 gene and CYP2J2 gene. The related lipids are Fatty Acids, Dietary Fatty Acid, stearidonic acid and Fatty Acids, Nonesterified. 4231
bishomo-gamma-linolenic acid Bishomo-gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. Bishomo-gamma-linolenic acid is associated with abnormalities such as Diabetes, Obesity, Hypertensive disease, Cirrhosis and Hepatorenal Syndrome. The involved functions are known as Oxidation, Process, Metabolic Inhibition, epoxide hydrolase activity and Signal Transduction Pathways. Bishomo-gamma-linolenic acid often locates in Protoplasm, Cytoplasmic matrix, soluble, Membrane and Tissue membrane. The associated genes with bishomo-gamma-linolenic acid are P4HTM gene, IMPACT gene, arginine methyl ester, CYP gene and PTGS1 gene. The related lipids are Fatty Acids, 17-octadecynoic acid, Lipopolysaccharides, palmitoleic acid and nervonic acid. The related experimental models are Knock-out and Mouse Model. 2467
20-HETE 20-hete is a lipid of Fatty Acyls (FA) class. 20-hete is associated with abnormalities such as Cyst, Kidney Diseases, Kidney Failure, Chronic, Cystic Kidney Diseases and Simple renal cyst. The involved functions are known as Phosphorylation, inhibitors, Hypertrophy, Epithelial Cell Proliferation and Anabolism. 20-hete often locates in Mouse Kidney, Microsomes, Tissue membrane, Body tissue and Cytoplasmic matrix. The associated genes with 20-HETE are CYP4F3 gene, PKHD1 gene, Transgenes, P4HTM gene and CYP2E1 gene. The related lipids are Promega, enterodiol, Fatty Acids, hexanoic acid and U 73343. The related experimental models are Mouse Model, Knock-out, Streptozotocin Diabetes, Transgenic Model and Rodent Model. 1257
11,12-eet 353
11s,12r-epetre 11s,12r-epetre is a lipid of Fatty Acyls (FA) class. 11s,12r-epetre is associated with abnormalities such as Hypertensive disease, Coronary Arteriosclerosis, Atherosclerosis, Ischemia and Vascular Diseases. The involved functions are known as inhibitors, Pathological Dilatation, Renal function, depolarization and Force. 11s,12r-epetre often locates in Body tissue, Epithelium, Cell membrane, apical membrane and Endothelium. The associated genes with 11s,12r-epetre are CYP2C18 gene, ADRBK1 gene, iberiotoxin and TNF gene. 353
11r,12s-epetre 11r,12s-epetre is a lipid of Fatty Acyls (FA) class. 11r,12s-epetre is associated with abnormalities such as Hypertensive disease, Coronary Arteriosclerosis, Atherosclerosis, Ischemia and Vascular Diseases. The involved functions are known as inhibitors, Pathological Dilatation, Renal function, depolarization and Force. 11r,12s-epetre often locates in Body tissue, Epithelium, Cell membrane, apical membrane and Endothelium. The associated genes with 11r,12s-epetre are CYP2C18 gene, ADRBK1 gene, iberiotoxin and TNF gene. 353
11,12-epetre 136
11,12-epoxyeicosatrienoic acid 143
beta-parinaric acid Beta-parinaric acid is a lipid of Fatty Acyls (FA) class. 416
DHA Dha is a lipid of Fatty Acyls (FA) class. Dha is associated with abnormalities such as Atherosclerosis, Consumption-archaic term for TB, Chronic disease, Cardiovascular Diseases and Diabetes Mellitus, Non-Insulin-Dependent. The involved functions are known as Inflammation, Oxidation, fatty acid oxidation, Fatty Acid Metabolism and Lipid Metabolism. Dha often locates in Hepatic, Protoplasm, Mucous Membrane, Epithelium and outer membrane. The associated genes with DHA are IMPACT gene, FATE1 gene, GAPDH gene, THOC4 gene and SLC33A1 gene. The related lipids are stearidonic acid, Fatty Acids, Total cholesterol, Lipopolysaccharides and Dietary Fatty Acid. The related experimental models are Mouse Model, Transgenic Model, Animal Disease Models and Arthritis, Experimental. 11054
7-octadecynoic acid 7-octadecynoic acid is a lipid of Fatty Acyls (FA) class. 8379
(r)-3-hydroxybutanoic acid (r)-3-hydroxybutanoic acid is a lipid of Fatty Acyls (FA) class. 2710
Pyruvic acid Pyruvic acid is a lipid of Fatty Acyls (FA) class. 27047
Dichloroacetic acid Dichloroacetic acid is a lipid of Fatty Acyls (FA) class. Dichloroacetic acid is associated with abnormalities such as Acidosis, Lactic, Metabolic Diseases, CLEFT LIP, CONGENITAL HEALED, Asthma and hyperthyroid. The involved functions are known as inhibitors, Chlorination, Metabolic Inhibition, Process and Sterility. Dichloroacetic acid often locates in Intestine - Large Intestine - Cecum (MMHCC), Mouse Liver, Back and Head. The associated genes with Dichloroacetic acid are GSTZ1 gene, PSMA5 gene and Maleylacetoacetate isomerase. The related lipids are Nonesterified Fatty Acids. 2361
6-aminohexanoic acid 6-aminohexanoic acid is a lipid of Fatty Acyls (FA) class. 6-aminohexanoic acid is associated with abnormalities such as Blood Clot, Myocardial Infarction, Cerebrovascular accident, Renal impairment and Scoliosis, unspecified. The involved functions are known as Fibrinolysis, Agent, Hemorrhage, plasminogen activation and inhibitors. 6-aminohexanoic acid often locates in Chest, Blood, Body tissue, peritoneal and Plasma membrane. The associated genes with 6-aminohexanoic acid are P4HTM gene, BSND gene, MTPN gene, NDUFS4 gene and Homologous Gene. The related lipids are Phosphatidylserines and Butyric Acid. 3685
4-aminobutyric acid 4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids. 19702
L-norvaline L-norvaline is a lipid of Fatty Acyls (FA) class. L-norvaline is associated with abnormalities such as Celiac Disease, Exanthema, Atherosclerosis, Plasmodium falciparum infection and Parasitemia. The involved functions are known as Anabolism, Saturated, Stimulus, Physiologic Organization and arginase activity. L-norvaline often locates in Extracellular, Protoplasm, soluble, viral nucleocapsid location and Cell Wall. The associated genes with L-norvaline are norvaline, Amino Acids, Basic, ARG1 gene, Escherichia coli Proteins and Operon. The related lipids are Lipopolysaccharides. 328
2,5-diaminopentanoic acid 2,5-diaminopentanoic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Vasodilation, Intestinal Absorption and Pinocytosis. 2,5-diaminopentanoic acid often locates in Mitochondria, Microfilaments, NADH dehydrogenase complex and respiratory chain complex III location sensu Eukarya. The associated genes with 2,5-diaminopentanoic acid are GAPDH gene and iberiotoxin. 8868
Lipoic acid Lipoic acid is a lipid of Fatty Acyls (FA) class. 7940
Prostaglandin E2 Prostaglandin E2 is a lipid of Fatty Acyls (FA) class. Prostaglandin e2 is associated with abnormalities such as Renal glomerular disease, Arthritis, Degenerative polyarthritis, Pancreatitis and Rheumatoid Arthritis. The involved functions are known as enzyme pathway, Atherogenesis, Anabolism, inhibitors and Oxidants. Prostaglandin e2 often locates in Tissue membrane, Blood, Extracellular, Membrane and Protoplasm. The associated genes with Prostaglandin E2 are PTGS2 gene, TP53 gene, TNFRSF5 gene, FASTK Gene and TNF gene. The related lipids are Lipopolysaccharides, Steroids, monooxyethylene trimethylolpropane tristearate, Fatty Acids, Unsaturated and Promega. The related experimental models are Arthritis, Adjuvant-Induced, Xenograft Model, Experimental Autoimmune Encephalomyelitis, Cancer Model and Knock-out. 49278
13,14-dihydro-15-keto-PGF2alpha 13,14-dihydro-15-keto-pgf2alpha is a lipid of Fatty Acyls (FA) class. 1147
11beta-PGF2 11beta-pgf2 is a lipid of Fatty Acyls (FA) class. 15009
15-F2t-IsoP 15-f2t-isop is a lipid of Fatty Acyls (FA) class. 15-f2t-isop is associated with abnormalities such as Diabetes Mellitus, Acute coronary syndrome, Risk factor, cardiovascular, thrombocytosis and Chronic ischemic heart disease NOS. The involved functions are known as Anabolism, Inflammation, Lipid Peroxidation, Excretory function and Platelet Activation. The associated genes with 15-F2t-IsoP are PTGS2 gene. 2120
PGF1alpha Pgf1alpha is a lipid of Fatty Acyls (FA) class. 418
Thromboxane b2 Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele. 10175
1-hexacosanol 1-hexacosanol is a lipid of Fatty Acyls (FA) class. 94
n-heptanol N-heptanol is a lipid of Fatty Acyls (FA) class. N-heptanol is associated with abnormalities such as Corneal Neovascularization. N-heptanol often locates in Epithelium and Structure of corneal epithelium. The related lipids are Heptanol. 984
4-hydroxynonenal 4-hydroxynonenal is a lipid of Fatty Acyls (FA) class. 4-hydroxynonenal is associated with abnormalities such as Chronic disease, Obesity, Diabetes, Acquired Immunodeficiency Syndrome and Lung diseases. The involved functions are known as protein expression, Glycolysis, mRNA Expression, Regulation and Mitochondrion in division. 4-hydroxynonenal often locates in Muscle, Mitochondria, Adipose tissue, Head and Mouse Muscle. The associated genes with 4-hydroxynonenal are STAT3 gene, SIRT1 gene, PGC gene, IL6 gene and cytochrome c''. The related lipids are Lipopolysaccharides, Lipid Peroxides, Promega, Membrane Lipids and oxidized lipid. The related experimental models are Mouse Model, Knock-out, Transgenic Model, Disease model and Rodent Model. 5685
O-propanoylcarnitine O-propanoylcarnitine is a lipid of Fatty Acyls (FA) class. 258
Anandamide Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine. 4747
Methyl vinyl ketone Methyl vinyl ketone is a lipid of Fatty Acyls (FA) class. 287
2-arachidonoylglycerol 2-arachidonoylglycerol is a lipid of Glycerolipids (GL) class. 2-arachidonoylglycerol is associated with abnormalities such as Atherosclerosis, Heart Diseases, Inflammatory disorder, Colitis and Peripheral Neuropathy. The involved functions are known as Immunoreactivity, inhibitors, Stimulus, Esthesia and Signal Transduction. 2-arachidonoylglycerol often locates in Back, Presynaptic Terminals, Brain region, Blood and Body tissue. The associated genes with 2-arachidonoylglycerol are ADRBK1 gene, Homologous Gene, MGLL gene, PLA2G4A gene and peptide V. The related lipids are oleoylethanolamide, Lipopolysaccharides, Promega, stearic acid and 1-stearoyl-2-arachidonoylglycerol. The related experimental models are Knock-out. 1892
1-octadecanoyl-sn-glycero-3-phosphocholine 1-octadecanoyl-sn-glycero-3-phosphocholine is a lipid of Glycerophospholipids (GP) class. 1-octadecanoyl-sn-glycero-3-phosphocholine is associated with abnormalities such as Septicemia. The involved functions are known as Phosphorylation, MAP kinase activity, Phagocytosis, protein serine/threonine kinase activity and Uptake. The associated genes with 1-octadecanoyl-sn-glycero-3-phosphocholine are FPR1 gene and OLR1 gene. The related lipids are Lysophosphatidylcholines. 42
trichostatin A Trichostatin is a lipid of Polyketides (PK) class. Trichostatin is associated with abnormalities such as Dentatorubral-Pallidoluysian Atrophy, PARAGANGLIOMAS 3, abnormal fragmented structure, Disintegration (morphologic abnormality) and Hyperostosis, Diffuse Idiopathic Skeletal. The involved functions are known as Acetylation, Cell Differentiation process, histone modification, Gene Silencing and Transcriptional Activation. Trichostatin often locates in CD41a, Hematopoietic System, Chromatin Structure, Blood and Endothelium. The associated genes with Trichostatin are SPI1 gene, CELL Gene, Chromatin, CXCR4 gene and DNMT1 gene. The related lipids are Butyrates, Promega, butyrate, Lipopolysaccharides and Steroids. The related experimental models are Knock-out, Mouse Model, Xenograft Model and Cancer Model. 5401
tacrolimus Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene. 12730
erythromycin erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out. 19871
minocycline minocycline is a lipid of Polyketides (PK) class. Minocycline is associated with abnormalities such as Infection, Soft Tissue Infections, Septicemia, Chronic hyponatremia and Lesion of brain. The involved functions are known as Pharmacodynamics, Gene Expression, Transcriptional Activation, Regulation and Process. Minocycline often locates in Ribosomes, 50S ribosomal subunit, Blood, Skin and Immune system. The associated genes with minocycline are THEMIS gene, KCNK2 gene, RBFOX3 gene, PIWIL2 gene and P4HTM gene. The related lipids are Lipopolysaccharides, Promega, Steroids, Liposomes and Octanols. The related experimental models are Mouse Model, Experimental Autoimmune Encephalomyelitis, Genetically Engineered Mouse, Disease model and spinal model. 9780
CYTOCHALASIN B CYTOCHALASIN B is a lipid of Polyketides (PK) class. Cytochalasin b is associated with abnormalities such as Renal tubular disorder and Chagas Disease. The involved functions are known as Membrane Protein Traffic, inhibitors, Metabolic Inhibition, Biochemical Pathway and Increased Sensitivy. Cytochalasin b often locates in Cytoplasmic matrix, Plasma membrane, Microtubules, Extracellular and Protoplasm. The associated genes with CYTOCHALASIN B are SLC2A2 gene, PFDN5 gene, SLC2A1 gene, OMG gene and SPEN gene. The related lipids are Steroids, Lipopolysaccharides and Liposomes. The related experimental models are Xenograft Model. 9648
(-)-Epigallocatechin gallate (-)-Epigallocatechin gallate is a lipid of Polyketides (PK) class. (-)-epigallocatechin gallate is associated with abnormalities such as IMMUNE SUPPRESSION, Infection, Nodule, Lymphopenia and Tumor Immunity. The involved functions are known as Apoptosis, Cellular Immune Response, Specific immune response, Signal and Infiltration. (-)-epigallocatechin gallate often locates in Immune system, Cytoplasmic Granules, Skin, Protoplasm and Body tissue. The associated genes with (-)-Epigallocatechin gallate are C8orf4 gene, Genes, vpr, MAPK8 gene, P4HTM gene and GAG Gene. The related lipids are Promega, Lipopolysaccharides, Palmitates, Fatty Acids and Sphingolipids. The related experimental models are Mouse Model, Xenograft Model, Transgenic Model, Experimental Autoimmune Encephalomyelitis and Arthritis, Collagen-Induced. 6551
SCHEMBL105486 Kakonein is a lipid of Polyketides (PK) class. Kakonein is associated with abnormalities such as Fatty Liver, Chronic liver disease, Morphologically altered structure, Hypertensive disease and Cardiovascular Diseases. The involved functions are known as protein expression, Extravasation, Liver damage, mRNA Expression and cell activation. Kakonein often locates in Body tissue, Hepatic, Microvilli, Cytoplasm and Membrane. The associated genes with Kakonein are TJP1 gene, CD14 gene, iberiotoxin, AT-Rich Interactive Domain-Containing Protein 1A and NKS1 gene. The related lipids are dehydrosoyasaponin I and Steroids. The related experimental models are Knock-out. 1391
formononetin Formononetin is a lipid of Polyketides (PK) class. Formononetin is associated with abnormalities such as Infection, Dehydration, Mycoses, Consumption-archaic term for TB and Syndrome. The involved functions are known as Protein Overexpression, Methylation, Esthesia, Anabolism and enzyme activity. Formononetin often locates in soluble, Cytoplasmic matrix, Body tissue, Membrane and Tissue membrane. The associated genes with Formononetin are IMPACT gene, GLUCOSIDASE, Genes, Reporter, IGKV1-16 gene and GAL gene. The related experimental models are Knock-out. 790
Calycosin Calycosin is a lipid of Polyketides (PK) class. Calycosin is associated with abnormalities such as Degenerative polyarthritis and Ischemia. The involved functions are known as Biosynthetic Pathways, Process, Anabolism, trans-cinnamate 4-hydroxylase activity and Transcription, Genetic. Calycosin often locates in viral nucleocapsid location, Mucous Membrane and Cell membrane. 195
daidzein daidzein is a lipid of Polyketides (PK) class. Daidzein is associated with abnormalities such as Cardiovascular Diseases, Osteoporosis, Heart Diseases, Thyroid Diseases and Exanthema. The involved functions are known as Cell Growth, Disease Progression, metaplastic cell transformation, Cell Cycle and M Phase Cell Cycle Arrest. Daidzein often locates in Urothelium, Mucous Membrane, Chromosomes, Epithelium and Ribosomes. The associated genes with daidzein are Tumor Suppressor Genes, Genome, TIRAP gene, TICAM2 gene and Candidate Disease Gene. The related lipids are Promega, Steroids, Saponins, enterodiol and linoleates. The related experimental models are Xenograft Model, Knock-out, Mouse Model, Breast Cancer Model and Arthritis, Experimental. 4463
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